Compile Data Set for Download or QSAR

Found 91 hits Enz. Inhib. hit(s) with all data for entry = 50003214   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50015640 (GALUNISERTIB | LY-2157299) Show SMILES Cc1cccc(n1)-c1nn2CCCc2c1-c1ccnc2ccc(cc12)C(N)=O |(13.61,.14,;12.84,-1.19,;13.61,-2.53,;12.84,-3.86,;11.3,-3.86,;10.53,-2.53,;11.3,-1.19,;8.99,-2.53,;8.08,-1.28,;6.62,-1.76,;5.15,-1.28,;4.25,-2.53,;5.15,-3.77,;6.62,-3.3,;8.08,-3.77,;8.56,-5.24,;10.06,-5.56,;10.54,-7.02,;9.51,-8.17,;8,-7.85,;6.97,-8.99,;5.47,-8.67,;4.99,-7.21,;6.02,-6.06,;7.53,-6.38,;3.48,-6.89,;3.01,-5.42,;2.45,-8.03,)| Show InChI InChI=1S/C22H19N5O/c1-13-4-2-5-18(25-13)21-20(19-6-3-11-27(19)26-21)15-9-10-24-17-8-7-14(22(23)28)12-16(15)17/h2,4-5,7-10,12H,3,6,11H2,1H3,(H2,23,28)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468220 (CHEMBL4277021) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccc(O)cc1 Show InChI InChI=1S/C21H23N3O/c1-13-6-5-7-17(22-13)19-18(15-8-10-16(25)11-9-15)20-14(2)21(3,4)12-24(20)23-19/h5-11,14,25H,12H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468197 (CHEMBL4285400) Show SMILES C[C@H]1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C21H23N3O/c1-13-6-5-7-17(22-13)19-18(15-8-10-16(25)11-9-15)20-14(2)21(3,4)12-24(20)23-19/h5-11,14,25H,12H2,1-4H3/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	97	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468203 (CHEMBL4287654) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccc(O)cc1 Show InChI InChI=1S/C22H25N3O/c1-5-16-7-6-8-18(23-16)20-19(15-9-11-17(26)12-10-15)21-14(2)22(3,4)13-25(21)24-20/h6-12,14,26H,5,13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	98	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468207 (CHEMBL4288745) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)[C@@H](C)c2c1-c1ccc(O)cc1 |r| Show InChI InChI=1S/C22H25N3O/c1-5-16-7-6-8-18(23-16)20-19(15-9-11-17(26)12-10-15)21-14(2)22(3,4)13-25(21)24-20/h6-12,14,26H,5,13H2,1-4H3/t14-/m0/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	137	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468201 (CHEMBL4292491) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C25H26N6O2S/c1-16-5-4-6-20(28-16)24-23(21-14-25(2,3)15-31(21)30-24)17-11-12-27-22(13-17)29-18-7-9-19(10-8-18)34(26,32)33/h4-13H,14-15H2,1-3H3,(H,27,29)(H2,26,32,33)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	147	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468206 (CHEMBL4291675) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C26H28N6O2S/c1-16-6-5-7-21(29-16)24-23(25-17(2)26(3,4)15-32(25)31-24)18-12-13-28-22(14-18)30-19-8-10-20(11-9-19)35(27,33)34/h5-14,17H,15H2,1-4H3,(H,28,30)(H2,27,33,34)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	154	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468204 (CHEMBL4289487) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccncc1 Show InChI InChI=1S/C22H22N4/c1-14-6-5-7-17(18(14)12-23)20-19(16-8-10-24-11-9-16)21-15(2)22(3,4)13-26(21)25-20/h5-11,15H,13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468218 (CHEMBL4279935) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccncc1 Show InChI InChI=1S/C20H22N4/c1-13-6-5-7-16(22-13)18-17(15-8-10-21-11-9-15)19-14(2)20(3,4)12-24(19)23-18/h5-11,14H,12H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1 Show InChI InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	181	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468213 (CHEMBL4281030) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccncc1 Show InChI InChI=1S/C21H24N4/c1-5-16-7-6-8-17(23-16)19-18(15-9-11-22-12-10-15)20-14(2)21(3,4)13-25(20)24-19/h6-12,14H,5,13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	183	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468215 (CHEMBL4277446) Show SMILES C[C@@H]1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C21H23N3O/c1-13-6-5-7-17(22-13)19-18(15-8-10-16(25)11-9-15)20-14(2)21(3,4)12-24(20)23-19/h5-11,14,25H,12H2,1-4H3/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	197	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468202 (CHEMBL4279172) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C27H30N6O2S/c1-5-19-7-6-8-22(30-19)25-24(26-17(2)27(3,4)16-33(26)32-25)18-13-14-29-23(15-18)31-20-9-11-21(12-10-20)36(28,34)35/h6-15,17H,5,16H2,1-4H3,(H,29,31)(H2,28,34,35)	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468196 (CHEMBL4291439) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccc(O)cc1 Show InChI InChI=1S/C20H21N3O/c1-13-5-4-6-16(21-13)19-18(14-7-9-15(24)10-8-14)17-11-20(2,3)12-23(17)22-19/h4-10,24H,11-12H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	229	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468195 (CHEMBL4283308) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)[C@H](C)c2c1-c1ccc(O)cc1 |r| Show InChI InChI=1S/C22H25N3O/c1-5-16-7-6-8-18(23-16)20-19(15-9-11-17(26)12-10-15)21-14(2)22(3,4)13-25(21)24-20/h6-12,14,26H,5,13H2,1-4H3/t14-/m1/s1	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	261	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468208 (CHEMBL4278812) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C23H23N3O/c1-14-6-5-7-18(19(14)12-24)21-20(16-8-10-17(27)11-9-16)22-15(2)23(3,4)13-26(22)25-21/h5-11,15,27H,13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	341	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468217 (CHEMBL4276896) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccncc1 Show InChI InChI=1S/C19H20N4/c1-13-5-4-6-15(21-13)18-17(14-7-9-20-10-8-14)16-11-19(2,3)12-23(16)22-18/h4-10H,11-12H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	406	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468214 (CHEMBL4284434) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(Cl)c1 Show InChI InChI=1S/C20H21ClN4/c1-12-6-5-7-15(23-12)18-17(14-8-9-22-16(21)10-14)19-13(2)20(3,4)11-25(19)24-18/h5-10,13H,11H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	517	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468193 (CHEMBL4287843) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(C)c1 Show InChI InChI=1S/C21H24N4/c1-13-7-6-8-17(23-13)19-18(16-9-10-22-14(2)11-16)20-15(3)21(4,5)12-25(20)24-19/h6-11,15H,12H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	548	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468206 (CHEMBL4291675) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C26H28N6O2S/c1-16-6-5-7-21(29-16)24-23(25-17(2)26(3,4)15-32(25)31-24)18-12-13-28-22(14-18)30-19-8-10-20(11-9-19)35(27,33)34/h5-14,17H,15H2,1-4H3,(H,28,30)(H2,27,33,34)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468219 (CHEMBL4292170) Show SMILES COc1ccc(cc1)-c1c(nn2CC(C)(C)C(C)c12)-c1cccc(C)n1 Show InChI InChI=1S/C22H25N3O/c1-14-7-6-8-18(23-14)20-19(16-9-11-17(26-5)12-10-16)21-15(2)22(3,4)13-25(21)24-20/h6-12,15H,13H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	612	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468221 (CHEMBL4292878) Show SMILES COCC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccncc1 Show InChI InChI=1S/C21H24N4O/c1-14-6-5-7-17(23-14)19-18(15-8-10-22-11-9-15)20-16(12-26-4)21(2,3)13-25(20)24-19/h5-11,16H,12-13H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	743	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468199 (CHEMBL4284266) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccc(OC)cc1 Show InChI InChI=1S/C23H27N3O/c1-6-17-8-7-9-19(24-17)21-20(16-10-12-18(27-5)13-11-16)22-15(2)23(3,4)14-26(22)25-21/h7-13,15H,6,14H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	805	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468211 (CHEMBL4284609) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccnc(Cl)c1 Show InChI InChI=1S/C19H19ClN4/c1-12-5-4-6-14(22-12)18-17(13-7-8-21-16(20)9-13)15-10-19(2,3)11-24(15)23-18/h4-9H,10-11H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468194 (CHEMBL4287261) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1ccccc1C#N)-c1ccncc1 Show InChI InChI=1S/C21H20N4/c1-14-20-18(15-8-10-23-11-9-15)19(24-25(20)13-21(14,2)3)17-7-5-4-6-16(17)12-22/h4-11,14H,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.29E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468200 (CHEMBL4282287) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)C(CO)c2c1-c1ccncc1 Show InChI InChI=1S/C20H22N4O/c1-13-5-4-6-16(22-13)18-17(14-7-9-21-10-8-14)19-15(11-25)20(2,3)12-24(19)23-18/h4-10,15,25H,11-12H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468209 (CHEMBL4285692) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccncc1 Show InChI InChI=1S/C18H18N4/c1-18(2)11-15-16(13-6-9-19-10-7-13)17(21-22(15)12-18)14-5-3-4-8-20-14/h3-10H,11-12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.94E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468210 (CHEMBL4281195) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccn1)-c1ccc(O)cc1 Show InChI InChI=1S/C19H19N3O/c1-19(2)11-16-17(13-6-8-14(23)9-7-13)18(21-22(16)12-19)15-5-3-4-10-20-15/h3-10,23H,11-12H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.99E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468212 (CHEMBL4294411) Show SMILES CCOC(=O)c1ccc(cc1)-c1c(nn2CC(C)(C)C(C)c12)-c1cccc(C)n1 Show InChI InChI=1S/C24H27N3O2/c1-6-29-23(28)18-12-10-17(11-13-18)20-21(19-9-7-8-15(2)25-19)26-27-14-24(4,5)16(3)22(20)27/h7-13,16H,6,14H2,1-5H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468201 (CHEMBL4292491) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C25H26N6O2S/c1-16-5-4-6-20(28-16)24-23(21-14-25(2,3)15-31(21)30-24)17-11-12-27-22(13-17)29-18-7-9-19(10-8-18)34(26,32)33/h4-13H,14-15H2,1-3H3,(H,27,29)(H2,26,32,33)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468205 (CHEMBL4277755) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccc1C#N)-c1ccncc1 Show InChI InChI=1S/C20H18N4/c1-20(2)11-17-18(14-7-9-22-10-8-14)19(23-24(17)13-20)16-6-4-3-5-15(16)12-21/h3-10H,11,13H2,1-2H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.52E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468198 (CHEMBL4287412) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccnc(Cl)c1 Show InChI InChI=1S/C21H23ClN4/c1-5-15-7-6-8-16(24-15)19-18(14-9-10-23-17(22)11-14)20-13(2)21(3,4)12-26(20)25-19/h6-11,13H,5,12H2,1-4H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
TGF-beta receptor type-1 (Homo sapiens (Human))	BDBM50468216 (CHEMBL4279331) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1ccccc1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C22H21N3O/c1-14-21-19(15-8-10-17(26)11-9-15)20(24-25(21)13-22(14,2)3)18-7-5-4-6-16(18)12-23/h4-11,14,26H,13H2,1-3H3	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.19E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human ALK5 expressed in Sf9 insect cells using casein as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468204 (CHEMBL4289487) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccncc1 Show InChI InChI=1S/C22H22N4/c1-14-6-5-7-17(18(14)12-23)20-19(16-8-10-24-11-9-16)21-15(2)22(3,4)13-26(21)25-20/h5-11,15H,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468202 (CHEMBL4279172) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C27H30N6O2S/c1-5-19-7-6-8-22(30-19)25-24(26-17(2)27(3,4)16-33(26)32-25)18-13-14-29-23(15-18)31-20-9-11-21(12-10-20)36(28,34)35/h6-15,17H,5,16H2,1-4H3,(H,29,31)(H2,28,34,35)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.80E+3	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468194 (CHEMBL4287261) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1ccccc1C#N)-c1ccncc1 Show InChI InChI=1S/C21H20N4/c1-14-20-18(15-8-10-23-11-9-15)19(24-25(20)13-21(14,2)3)17-7-5-4-6-16(17)12-22/h4-11,14H,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50468206 (CHEMBL4291675) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C26H28N6O2S/c1-16-6-5-7-21(29-16)24-23(25-17(2)26(3,4)15-32(25)31-24)18-12-13-28-22(14-18)30-19-8-10-20(11-9-19)35(27,33)34/h5-14,17H,15H2,1-4H3,(H,28,30)(H2,27,33,34)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468208 (CHEMBL4278812) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C23H23N3O/c1-14-6-5-7-18(19(14)12-24)21-20(16-8-10-17(27)11-9-16)22-15(2)23(3,4)13-26(22)25-21/h5-11,15,27H,13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50468208 (CHEMBL4278812) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)c1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C23H23N3O/c1-14-6-5-7-18(19(14)12-24)21-20(16-8-10-17(27)11-9-16)22-15(2)23(3,4)13-26(22)25-21/h5-11,15,27H,13H2,1-4H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468216 (CHEMBL4279331) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1ccccc1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C22H21N3O/c1-14-21-19(15-8-10-17(26)11-9-15)20(24-25(21)13-22(14,2)3)18-7-5-4-6-16(18)12-23/h4-11,14,26H,13H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50468216 (CHEMBL4279331) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1ccccc1C#N)-c1ccc(O)cc1 Show InChI InChI=1S/C22H21N3O/c1-14-21-19(15-8-10-17(26)11-9-15)20(24-25(21)13-22(14,2)3)18-7-5-4-6-16(18)12-23/h4-11,14,26H,13H2,1-3H3	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468205 (CHEMBL4277755) Show SMILES CC1(C)Cc2c(c(nn2C1)-c1ccccc1C#N)-c1ccncc1 Show InChI InChI=1S/C20H18N4/c1-20(2)11-17-18(14-7-9-22-10-8-14)19(23-24(17)13-20)16-6-4-3-5-15(16)12-21/h3-10H,11,13H2,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468196 (CHEMBL4291439) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccc(O)cc1 Show InChI InChI=1S/C20H21N3O/c1-13-5-4-6-16(21-13)19-18(14-7-9-15(24)10-8-14)17-11-20(2,3)12-23(17)22-19/h4-10,24H,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50151347 (2-(3-(6-methylpyridin-2-yl)-1H-pyrazol-4-yl)-1,5-n...) Show SMILES Cc1cccc(n1)-c1n[nH]cc1-c1ccc2ncccc2n1 Show InChI InChI=1S/C17H13N5/c1-11-4-2-5-16(20-11)17-12(10-19-22-17)13-7-8-14-15(21-13)6-3-9-18-14/h2-10H,1H3,(H,19,22)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL MCE MMDB PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468218 (CHEMBL4279935) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccncc1 Show InChI InChI=1S/C20H22N4/c1-13-6-5-7-16(22-13)18-17(15-8-10-21-11-9-15)19-14(2)20(3,4)12-24(19)23-18/h5-11,14H,12H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50468215 (CHEMBL4277446) Show SMILES C[C@@H]1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccc(O)cc1 |r| Show InChI InChI=1S/C21H23N3O/c1-13-6-5-7-17(22-13)19-18(15-8-10-16(25)11-9-15)20-14(2)21(3,4)12-24(20)23-19/h5-11,14,25H,12H2,1-4H3/t14-/m1/s1	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468221 (CHEMBL4292878) Show SMILES COCC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccncc1 Show InChI InChI=1S/C21H24N4O/c1-14-6-5-7-17(23-14)19-18(15-8-10-22-11-9-15)20-16(12-26-4)21(2,3)13-25(20)24-19/h5-11,16H,12-13H2,1-4H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468193 (CHEMBL4287843) Show SMILES CC1c2c(c(nn2CC1(C)C)-c1cccc(C)n1)-c1ccnc(C)c1 Show InChI InChI=1S/C21H24N4/c1-13-7-6-8-17(23-13)19-18(16-9-10-22-14(2)11-16)20-15(3)21(4,5)12-25(20)24-19/h6-11,15H,12H2,1-5H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Tyrosine-protein kinase ABL1 (Mus musculus)	BDBM50468217 (CHEMBL4276896) Show SMILES Cc1cccc(n1)-c1nn2CC(C)(C)Cc2c1-c1ccncc1 Show InChI InChI=1S/C19H20N4/c1-13-5-4-6-15(21-13)18-17(14-7-9-20-10-8-14)16-11-19(2,3)12-23(16)22-18/h4-10H,11-12H2,1-3H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of mouse ABL expressed in Sf9 insect cells using GGEAIYAAPFKK as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair
Cyclin-dependent kinase 2/G1/S-specific cyclin-E1 (Homo sapiens (Human))	BDBM50468202 (CHEMBL4279172) Show SMILES CCc1cccc(n1)-c1nn2CC(C)(C)C(C)c2c1-c1ccnc(Nc2ccc(cc2)S(N)(=O)=O)c1 Show InChI InChI=1S/C27H30N6O2S/c1-5-19-7-6-8-22(30-19)25-24(26-17(2)27(3,4)16-33(26)32-25)18-13-14-29-23(15-18)31-20-9-11-21(12-10-20)36(28,34)35/h6-15,17H,5,16H2,1-4H3,(H,29,31)(H2,28,34,35)	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Palack£ University and Institute of Experimental Botany AS CR Curated by ChEMBL					Assay Description Inhibition of human CDK2/cyclin E expressed in Sf9 insect cells using histone H1 as substrate in presence of [gamma-33P]ATP				Eur J Med Chem 127: 632-642 (2017) Article DOI: 10.1016/j.ejmech.2017.01.018 BindingDB Entry DOI: 10.7270/Q29Z97MF
					More data for this Ligand-Target Pair

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