Compile Data Set for Download or QSAR

Found 38 hits Enz. Inhib. hit(s) with all data for entry = 50003495   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50058715 (CHEMBL64360 | EMD-96785 | ENIPORIDE | N-(5-Methane...) Show SMILES Cc1cc(c(cc1C(=O)NC(N)=N)S(C)(=O)=O)-n1cccc1 Show InChI InChI=1S/C14H16N4O3S/c1-9-7-11(18-5-3-4-6-18)12(22(2,20)21)8-10(9)13(19)17-14(15)16/h3-8H,1-2H3,(H4,15,16,17,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471819 (CHEMBL332433) Show SMILES [#6]-c1cc2-[#6](=[#6])C([#6])([#6])S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C14H17N3O3S/c1-7-5-10-8(2)14(3,4)21(19,20)11(10)6-9(7)12(18)17-13(15)16/h5-6H,2H2,1,3-4H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471814 (CHEMBL126367) Show SMILES [#6]-[#6]1-c2cc(-[#6])c(cc2S(=O)(=O)C1([#6])[#6])-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C14H19N3O3S/c1-7-5-10-8(2)14(3,4)21(19,20)11(10)6-9(7)12(18)17-13(15)16/h5-6,8H,1-4H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471802 (CHEMBL124274) Show SMILES [#6]-c1cc2\[#6](-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])=[#7]\[#8] Show InChI InChI=1S/C11H12N4O4S/c1-5-2-7-8(15-17)4-20(18,19)9(7)3-6(5)10(16)14-11(12)13/h2-3,17H,4H2,1H3,(H4,12,13,14,16)/b15-8+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471801 (CHEMBL331794) Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7])S(=O)(=O)C([#6])([#6])C2([#6])[#8] Show InChI InChI=1S/C14H19N3O4S/c1-7-5-9-10(6-8(7)11(18)17-12(15)16)22(20,21)13(2,3)14(9,4)19/h5-6,19H,1-4H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471791 (CHEMBL439605) Show SMILES [#6]-c1cc2-[#6]-[#6]-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C13H17N3O3S/c1-8-6-9-4-2-3-5-20(18,19)11(9)7-10(8)12(17)16-13(14)15/h6-7H,2-5H2,1H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471796 (CHEMBL124547) Show SMILES [#6]-[#6](-[#6])-[#6]-1-[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C14H19N3O3S/c1-7(2)11-6-21(19,20)12-5-9(8(3)4-10(11)12)13(18)17-14(15)16/h4-5,7,11H,6H2,1-3H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471794 (CHEMBL124044) Show SMILES [#6]-[#6]-[#6]-1-[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C13H17N3O3S/c1-3-8-6-20(18,19)11-5-9(7(2)4-10(8)11)12(17)16-13(14)15/h4-5,8H,3,6H2,1-2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50234609 (Cariporide | HOE-642) Show SMILES [#6]-[#6](-[#6])-c1ccc(cc1S([#6])(=O)=O)-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C12H17N3O3S/c1-7(2)9-5-4-8(11(16)15-12(13)14)6-10(9)19(3,17)18/h4-7H,1-3H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471811 (CHEMBL126060) Show SMILES [#6]-[#8]-[#6]1-c2cc(-[#6])c(cc2S(=O)(=O)C1([#6])[#6])-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C14H19N3O4S/c1-7-5-9-10(6-8(7)12(18)17-13(15)16)22(19,20)14(2,3)11(9)21-4/h5-6,11H,1-4H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471823 (CHEMBL341296) Show SMILES [#6]-c1cc2-[#8]-[#6]-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C12H15N3O4S/c1-7-5-9-10(20(17,18)4-2-3-19-9)6-8(7)11(16)15-12(13)14/h5-6H,2-4H2,1H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471812 (CHEMBL331630) Show SMILES [#6]-c1cc2-[#6](-[#8])C([#6])([#6])S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C13H17N3O4S/c1-6-4-8-9(5-7(6)11(18)16-12(14)15)21(19,20)13(2,3)10(8)17/h4-5,10,17H,1-3H3,(H4,14,15,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471815 (CHEMBL123578) Show SMILES [#6]-c1cc2-[#6](=[#6])-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C13H15N3O3S/c1-7-3-4-20(18,19)11-6-10(8(2)5-9(7)11)12(17)16-13(14)15/h5-6H,1,3-4H2,2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471805 (CHEMBL122142) Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S(=O)(=O)[#6]C2([#6])[#8] Show InChI InChI=1S/C12H15N3O4S/c1-6-3-8-9(20(18,19)5-12(8,2)17)4-7(6)10(16)15-11(13)14/h3-4,17H,5H2,1-2H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471808 (CHEMBL333059) Show SMILES [#6]-[#6]C1([#8])[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc12 Show InChI InChI=1S/C13H17N3O4S/c1-3-13(18)6-21(19,20)10-5-8(7(2)4-9(10)13)11(17)16-12(14)15/h4-5,18H,3,6H2,1-2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471803 (CHEMBL123859) Show SMILES [#6]-c1cc2-[#8]-[#6]C([#6])([#6])S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C13H17N3O4S/c1-7-4-9-10(5-8(7)11(17)16-12(14)15)21(18,19)13(2,3)6-20-9/h4-5H,6H2,1-3H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471804 (CHEMBL421240) Show SMILES [#6]-[#6]-1-[#6]C([#6])([#6])S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C15H21N3O3S/c1-8-5-10-9(2)7-15(3,4)22(20,21)12(10)6-11(8)13(19)18-14(16)17/h5-6,9H,7H2,1-4H3,(H4,16,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471813 (CHEMBL331457) Show SMILES [#6]-[#8]C1([#6])[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc12 Show InChI InChI=1S/C13H17N3O4S/c1-7-4-9-10(5-8(7)11(17)16-12(14)15)21(18,19)6-13(9,2)20-3/h4-5H,6H2,1-3H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471807 (CHEMBL125283) Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S(=O)(=O)[#6]C2([#8])[#6](=O)-c1ccccc1 Show InChI InChI=1S/C18H17N3O5S/c1-10-7-13-14(8-12(10)16(23)21-17(19)20)27(25,26)9-18(13,24)15(22)11-5-3-2-4-6-11/h2-8,24H,9H2,1H3,(H4,19,20,21,23)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471818 (CHEMBL273539) Show SMILES [#6]-[#6]-1-[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C12H15N3O3S/c1-6-3-8-7(2)5-19(17,18)10(8)4-9(6)11(16)15-12(13)14/h3-4,7H,5H2,1-2H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471795 (CHEMBL123160) Show SMILES [#6]-[#8]\[#7]=[#6]-1/[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C12H14N4O4S/c1-6-3-8-9(16-20-2)5-21(18,19)10(8)4-7(6)11(17)15-12(13)14/h3-4H,5H2,1-2H3,(H4,13,14,15,17)/b16-9+	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471816 (CHEMBL125952) Show SMILES [#6]-[#6]-1-[#6]-[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](\[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C13H17N3O3S/c1-7-3-4-20(18,19)11-6-10(8(2)5-9(7)11)12(17)16-13(14)15/h5-7H,3-4H2,1-2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	45	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471790 (CHEMBL333480) Show SMILES [#6]\[#6](-[#6])=[#6]-1\[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](/[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C14H17N3O3S/c1-7(2)11-6-21(19,20)12-5-9(8(3)4-10(11)12)13(18)17-14(15)16/h4-5H,6H2,1-3H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471820 (CHEMBL330935) Show SMILES [#6]-[#6]1-[#6](-[#7])-c2cc(-[#6])c(cc2S1(=O)=O)-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C12H16N4O3S/c1-5-3-8-9(20(18,19)6(2)10(8)13)4-7(5)11(17)16-12(14)15/h3-4,6,10H,13H2,1-2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471799 (CHEMBL124884) Show SMILES [#6]-c1cc2-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C11H13N3O3S/c1-6-4-7-2-3-18(16,17)9(7)5-8(6)10(15)14-11(12)13/h4-5H,2-3H2,1H3,(H4,12,13,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471797 (CHEMBL124762) Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7])S(=O)(=O)[#6]C21[#8]-[#6]-[#6]-[#8]1 Show InChI InChI=1S/C13H15N3O5S/c1-7-4-9-10(5-8(7)11(17)16-12(14)15)22(18,19)6-13(9)20-2-3-21-13/h4-5H,2-3,6H2,1H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471809 (CHEMBL333804) Show SMILES [#6]-c1cc2-[#6](-[#8])-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C11H13N3O4S/c1-5-2-7-8(15)4-19(17,18)9(7)3-6(5)10(16)14-11(12)13/h2-3,8,15H,4H2,1H3,(H4,12,13,14,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471817 (CHEMBL122853) Show SMILES [#6]-c1cc2-[#6](=O)C([#6])([#6])S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C13H15N3O4S/c1-6-4-8-9(5-7(6)11(18)16-12(14)15)21(19,20)13(2,3)10(8)17/h4-5H,1-3H3,(H4,14,15,16,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471792 (CHEMBL340249) Show SMILES [#6]-c1cc2-[#6]-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C12H15N3O3S/c1-7-5-8-3-2-4-19(17,18)10(8)6-9(7)11(16)15-12(13)14/h5-6H,2-4H2,1H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	95	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471821 (CHEMBL121732) Show SMILES [#6]-c1cc2-[#6](=O)-[#6]-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C12H13N3O4S/c1-6-4-8-9(16)2-3-20(18,19)10(8)5-7(6)11(17)15-12(13)14/h4-5H,2-3H2,1H3,(H4,13,14,15,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471810 (CHEMBL445376) Show SMILES [#6]-[#8]-[#6]-1-[#6]S(=O)(=O)c2cc(-[#6](=O)\[#7]=[#6](/[#7])-[#7])c(-[#6])cc-12 Show InChI InChI=1S/C12H15N3O4S/c1-6-3-8-9(19-2)5-20(17,18)10(8)4-7(6)11(16)15-12(13)14/h3-4,9H,5H2,1-2H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471806 (CHEMBL125951) Show SMILES [#6]-c1cc2-[#6](-[#7])-[#6]S(=O)(=O)c2cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C11H14N4O3S/c1-5-2-7-8(12)4-19(17,18)9(7)3-6(5)10(16)15-11(13)14/h2-3,8H,4,12H2,1H3,(H4,13,14,15,16)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	116	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471793 (CHEMBL121787) Show SMILES [#6]-c1cc2c(cc1-[#6](=O)\[#7]=[#6](\[#7])-[#7])S(=O)(=O)[#6]-[#6]C21[#8]-[#6]-[#6]-[#8]1 Show InChI InChI=1S/C14H17N3O5S/c1-8-6-10-11(7-9(8)12(18)17-13(15)16)23(19,20)5-2-14(10)21-3-4-22-14/h6-7H,2-5H2,1H3,(H4,15,16,17,18)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471798 (CHEMBL122238) Show SMILES [#6]C1([#6])[#6]C([#6])([#6])S(=O)(=O)c2cc(ccc12)-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C15H21N3O3S/c1-14(2)8-15(3,4)22(20,21)11-7-9(5-6-10(11)14)12(19)18-13(16)17/h5-7H,8H2,1-4H3,(H4,16,17,18,19)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	360	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471824 (CHEMBL124987) Show SMILES [#6]-[#8]-[#6]-1-[#6]S(=O)(=O)c2cc(ccc-12)-[#6](=O)\[#7]=[#6](/[#7])-[#7] Show InChI InChI=1S/C11H13N3O4S/c1-18-8-5-19(16,17)9-4-6(2-3-7(8)9)10(15)14-11(12)13/h2-4,8H,5H2,1H3,(H4,12,13,14,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	700	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471822 (CHEMBL124826) Show SMILES NC(=N)NC(=O)c1ccc2CCS(=O)(=O)c2c1 Show InChI InChI=1S/C10H11N3O3S/c11-10(12)13-9(14)7-2-1-6-3-4-17(15,16)8(6)5-7/h1-2,5H,3-4H2,(H4,11,12,13,14)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	790	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471800 (CHEMBL333112) Show SMILES NC(=N)NC(=O)c1ccc2C(O)CS(=O)(=O)c2c1 Show InChI InChI=1S/C10H11N3O4S/c11-10(12)13-9(15)5-1-2-6-7(14)4-18(16,17)8(6)3-5/h1-3,7,14H,4H2,(H4,11,12,13,15)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair
Sodium/hydrogen exchanger 3 (Oryctolagus cuniculus)	BDBM50471789 (CHEMBL419609) Show SMILES [#6]C1([#6])[#6]-[#6]S(=O)(=O)c2cc(ccc12)-[#6](=O)\[#7]=[#6](\[#7])-[#7] Show InChI InChI=1S/C13H17N3O3S/c1-13(2)5-6-20(18,19)10-7-8(3-4-9(10)13)11(17)16-12(14)15/h3-4,7H,5-6H2,1-2H3,(H4,14,15,16,17)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Merck KGaA Curated by ChEMBL					Assay Description Sodium/hydrogen exchanger antiport activity was measured using [22]Na+ uptake inhibition assay in acidified rabbit erythrocytes				J Med Chem 41: 3736-47 (1998) Article DOI: 10.1021/jm981031w BindingDB Entry DOI: 10.7270/Q2BK1G33
					More data for this Ligand-Target Pair