Found 35 hits Enz. Inhib. hit(s) with all data for entry = 50003913 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477454
(CHEMBL245688)Show SMILES COc1cc(\C=C\c2cc(Br)cc(\C=C\c3ccc(O)c(OC)c3)c2)ccc1O Show InChI InChI=1S/C24H21BrO4/c1-28-23-14-16(7-9-21(23)26)3-5-18-11-19(13-20(25)12-18)6-4-17-8-10-22(27)24(15-17)29-2/h3-15,26-27H,1-2H3/b5-3+,6-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 100 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477429
(CHEMBL248132)Show SMILES COc1ccc(\C=C\c2cccc(\C=C\c3ccc(OC)c(N)c3)c2)cc1N Show InChI InChI=1S/C24H24N2O2/c1-27-23-12-10-19(15-21(23)25)8-6-17-4-3-5-18(14-17)7-9-20-11-13-24(28-2)22(26)16-20/h3-16H,25-26H2,1-2H3/b8-6+,9-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 300 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477447
(CHEMBL248327)Show SMILES CNc1cc(\C=C\c2cccc(\C=C\c3ccc(O)c(NC)c3)n2)ccc1O Show InChI InChI=1S/C23H23N3O2/c1-24-20-14-16(8-12-22(20)27)6-10-18-4-3-5-19(26-18)11-7-17-9-13-23(28)21(15-17)25-2/h3-15,24-25,27-28H,1-2H3/b10-6+,11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477441
(CHEMBL247674)Show SMILES CNc1ccc(\C=C\c2cccc(\C=C\c3ccc(NC)c(OC)c3)n2)cc1OC Show InChI InChI=1S/C25H27N3O2/c1-26-22-14-10-18(16-24(22)29-3)8-12-20-6-5-7-21(28-20)13-9-19-11-15-23(27-2)25(17-19)30-4/h5-17,26-27H,1-4H3/b12-8+,13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 500 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50105462
(CHEMBL81880 | N,N,N',N'-Tetramethyl-acridine-3,6-d...)Show InChI InChI=1S/C17H19N3/c1-19(2)14-7-5-12-9-13-6-8-15(20(3)4)11-17(13)18-16(12)10-14/h5-11H,1-4H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL MCE KEGG PC cid PC sid UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477456
(CHEMBL392878)Show SMILES COc1ccc(\C=C\c2cccc(\C=C\c3ccc(OC)c(N)c3)n2)cc1N Show InChI InChI=1S/C23H23N3O2/c1-27-22-12-8-16(14-20(22)24)6-10-18-4-3-5-19(26-18)11-7-17-9-13-23(28-2)21(25)15-17/h3-15H,24-25H2,1-2H3/b10-6+,11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477437
(CHEMBL247930)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(N)c(OC)c3)c2)ccc1N Show InChI InChI=1S/C24H24N2O2/c1-27-23-15-19(10-12-21(23)25)8-6-17-4-3-5-18(14-17)7-9-20-11-13-22(26)24(16-20)28-2/h3-16H,25-26H2,1-2H3/b8-6+,9-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477434
(CHEMBL247931)Show SMILES CNc1ccc(\C=C\c2cccc(\C=C\c3ccc(NC)c(OC)c3)c2)cc1OC Show InChI InChI=1S/C26H28N2O2/c1-27-23-14-12-21(17-25(23)29-3)10-8-19-6-5-7-20(16-19)9-11-22-13-15-24(28-2)26(18-22)30-4/h5-18,27-28H,1-4H3/b10-8+,11-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 600 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477428
(CHEMBL248131)Show SMILES CN(C)c1ccc(\C=C\c2cccc(\C=C\c3ccc(N(C)C)c(O)c3)c2)cc1O Show InChI InChI=1S/C26H28N2O2/c1-27(2)23-14-12-21(17-25(23)29)10-8-19-6-5-7-20(16-19)9-11-22-13-15-24(28(3)4)26(30)18-22/h5-18,29-30H,1-4H3/b10-8+,11-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477439
(CHEMBL247524)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(N)c(OC)c3)n2)ccc1N Show InChI InChI=1S/C23H23N3O2/c1-27-22-14-16(8-12-20(22)24)6-10-18-4-3-5-19(26-18)11-7-17-9-13-21(25)23(15-17)28-2/h3-15H,24-25H2,1-2H3/b10-6+,11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 700 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50067040
(((E,E)-1,7-bis(4-hydroxy-3-methoxyphenyl)-1,6-hept...)Show SMILES COc1cc(C=CC(=O)CC(=O)C=Cc2ccc(O)c(OC)c2)ccc1O |w:12.11,5.4| Show InChI InChI=1S/C21H20O6/c1-26-20-11-14(5-9-18(20)24)3-7-16(22)13-17(23)8-4-15-6-10-19(25)21(12-15)27-2/h3-12,24-25H,13H2,1-2H3 | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| Purchase
CHEMBL PC cid PC sid PDB UniChem
Patents
Similars
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477426
(CHEMBL391205)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(N(C)C)c(OC)c3)n2)ccc1N(C)C Show InChI InChI=1S/C27H31N3O2/c1-29(2)24-16-12-20(18-26(24)31-5)10-14-22-8-7-9-23(28-22)15-11-21-13-17-25(30(3)4)27(19-21)32-6/h7-19H,1-6H3/b14-10+,15-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477435
(CHEMBL247328)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(O)c(OC)c3)n2)ccc1O Show InChI InChI=1S/C23H21NO4/c1-27-22-14-16(8-12-20(22)25)6-10-18-4-3-5-19(24-18)11-7-17-9-13-21(26)23(15-17)28-2/h3-15,25-26H,1-2H3/b10-6+,11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 800 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477444
(CHEMBL247927)Show SMILES CN(C)c1ccc(\C=C\c2cccc(\C=C\c3ccc(N(C)C)c(O)c3)n2)cc1O Show InChI InChI=1S/C25H27N3O2/c1-27(2)22-14-10-18(16-24(22)29)8-12-20-6-5-7-21(26-20)13-9-19-11-15-23(28(3)4)25(30)17-19/h5-17,29-30H,1-4H3/b12-8+,13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477450
(CHEMBL247725)Show SMILES CNc1ccc(\C=C\c2cccc(\C=C\c3ccc(NC)c(O)c3)n2)cc1O Show InChI InChI=1S/C23H23N3O2/c1-24-20-12-8-16(14-22(20)27)6-10-18-4-3-5-19(26-18)11-7-17-9-13-21(25-2)23(28)15-17/h3-15,24-25,27-28H,1-2H3/b10-6+,11-7+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477446
(CHEMBL394713)Show SMILES COc1ccc(\C=C\c2cccc(\C=C\c3ccc(OC)c(c3)N(C)C)n2)cc1N(C)C Show InChI InChI=1S/C27H31N3O2/c1-29(2)24-18-20(12-16-26(24)31-5)10-14-22-8-7-9-23(28-22)15-11-21-13-17-27(32-6)25(19-21)30(3)4/h7-19H,1-6H3/b14-10+,15-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 900 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477448
(CHEMBL247932)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(N(C)C)c(OC)c3)c2)ccc1N(C)C Show InChI InChI=1S/C28H32N2O2/c1-29(2)25-16-14-23(19-27(25)31-5)12-10-21-8-7-9-22(18-21)11-13-24-15-17-26(30(3)4)28(20-24)32-6/h7-20H,1-6H3/b12-10+,13-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477438
(CHEMBL248122)Show SMILES CNc1cc(\C=C\c2cccc(\C=C\c3ccc(OC)c(NC)c3)n2)ccc1OC Show InChI InChI=1S/C25H27N3O2/c1-26-22-16-18(10-14-24(22)29-3)8-12-20-6-5-7-21(28-20)13-9-19-11-15-25(30-4)23(17-19)27-2/h5-17,26-27H,1-4H3/b12-8+,13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477455
(CHEMBL247929)Show SMILES COc1cc(\C=C\c2cc(Br)cc(\C=C\c3ccc(N)c(OC)c3)n2)ccc1N Show InChI InChI=1S/C23H22BrN3O2/c1-28-22-11-15(5-9-20(22)25)3-7-18-13-17(24)14-19(27-18)8-4-16-6-10-21(26)23(12-16)29-2/h3-14H,25-26H2,1-2H3/b7-3+,8-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477436
(CHEMBL247530)Show SMILES COc1cc(\C=C\c2cc(Cl)cc(\C=C\c3ccc(O)c(OC)c3)n2)ccc1O Show InChI InChI=1S/C23H20ClNO4/c1-28-22-11-15(5-9-20(22)26)3-7-18-13-17(24)14-19(25-18)8-4-16-6-10-21(27)23(12-16)29-2/h3-14,26-27H,1-2H3/b7-3+,8-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477431
(CHEMBL427878)Show SMILES COc1cc(\C=C\c2cc(Br)cc(\C=C\c3ccc(O)c(OC)c3)n2)ccc1O Show InChI InChI=1S/C23H20BrNO4/c1-28-22-11-15(5-9-20(22)26)3-7-18-13-17(24)14-19(25-18)8-4-16-6-10-21(27)23(12-16)29-2/h3-14,26-27H,1-2H3/b7-3+,8-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477453
(CHEMBL248337)Show SMILES COc1ccc(\C=C\c2cccc(\C=C\c3ccc(OC)c(c3)N(C)C)c2)cc1N(C)C Show InChI InChI=1S/C28H32N2O2/c1-29(2)25-19-23(14-16-27(25)31-5)12-10-21-8-7-9-22(18-21)11-13-24-15-17-28(32-6)26(20-24)30(3)4/h7-20H,1-6H3/b12-10+,13-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.10E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477433
(CHEMBL248133)Show SMILES CNc1cc(\C=C\c2cccc(\C=C\c3ccc(OC)c(NC)c3)c2)ccc1OC Show InChI InChI=1S/C26H28N2O2/c1-27-23-17-21(12-14-25(23)29-3)10-8-19-6-5-7-20(16-19)9-11-22-13-15-26(30-4)24(18-22)28-2/h5-18,27-28H,1-4H3/b10-8+,11-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477451
(CHEMBL247727)Show SMILES COc1cc(\C=C\c2cc(C)cc(\C=C\c3ccc(O)c(OC)c3)n2)ccc1O Show InChI InChI=1S/C24H23NO4/c1-16-12-19(8-4-17-6-10-21(26)23(14-17)28-2)25-20(13-16)9-5-18-7-11-22(27)24(15-18)29-3/h4-15,26-27H,1-3H3/b8-4+,9-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477445
(CHEMBL247726)Show SMILES COc1cc(\C=C\c2ccc(O)c(OC)c2)nc(\C=C\c2ccc(O)c(OC)c2)c1 Show InChI InChI=1S/C24H23NO5/c1-28-20-14-18(8-4-16-6-10-21(26)23(12-16)29-2)25-19(15-20)9-5-17-7-11-22(27)24(13-17)30-3/h4-15,26-27H,1-3H3/b8-4+,9-5+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477452
(CHEMBL396917)Show SMILES COc1cc(\C=C\c2cc(Br)cc(\C=C\c3ccc(N)c(OC)c3)c2)ccc1N Show InChI InChI=1S/C24H23BrN2O2/c1-28-23-14-16(7-9-21(23)26)3-5-18-11-19(13-20(25)12-18)6-4-17-8-10-22(27)24(15-17)29-2/h3-15H,26-27H2,1-2H3/b5-3+,6-4+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477432
(CHEMBL247728)Show SMILES COc1cc(\C=C\c2cc(cc(\C=C\c3ccc(O)c(OC)c3)n2)N(C)C)ccc1O Show InChI InChI=1S/C25H26N2O4/c1-27(2)21-15-19(9-5-17-7-11-22(28)24(13-17)30-3)26-20(16-21)10-6-18-8-12-23(29)25(14-18)31-4/h5-16,28-29H,1-4H3/b9-5+,10-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 1.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477443
(CHEMBL427877)Show SMILES CN(C)c1cc(\C=C\c2cccc(\C=C\c3ccc(O)c(c3)N(C)C)n2)ccc1O Show InChI InChI=1S/C25H27N3O2/c1-27(2)22-16-18(10-14-24(22)29)8-12-20-6-5-7-21(26-20)13-9-19-11-15-25(30)23(17-19)28(3)4/h5-17,29-30H,1-4H3/b12-8+,13-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.30E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477425
(CHEMBL248338)Show SMILES CN(C)c1cc(\C=C\c2cccc(\C=C\c3ccc(O)c(c3)N(C)C)c2)ccc1O Show InChI InChI=1S/C26H28N2O2/c1-27(2)23-17-21(12-14-25(23)29)10-8-19-6-5-7-20(16-19)9-11-22-13-15-26(30)24(18-22)28(3)4/h5-18,29-30H,1-4H3/b10-8+,11-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50204084
(5-((E)-2-{4-[(E)-2-(3-carboxy-4-hydroxyphenyl)viny...)Show SMILES OC(=O)c1cc(\C=C\c2ccc(\C=C\c3ccc(O)c(c3)C(O)=O)c(I)c2)ccc1O Show InChI InChI=1S/C24H17IO6/c25-20-13-16(2-1-14-5-9-21(26)18(11-14)23(28)29)4-8-17(20)7-3-15-6-10-22(27)19(12-15)24(30)31/h1-13,26-27H,(H,28,29)(H,30,31)/b2-1+,7-3+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article PubMed
| n/a | n/a | 8.00E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477430
(CHEMBL245477)Show SMILES CN(C)c1ccc(\C=C\c2cccc(\C=C\c3ccc(cc3)N(C)C)c2)cc1 Show InChI InChI=1S/C26H28N2/c1-27(2)25-16-12-21(13-17-25)8-10-23-6-5-7-24(20-23)11-9-22-14-18-26(19-15-22)28(3)4/h5-20H,1-4H3/b10-8+,11-9+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477440
(CHEMBL245478)Show SMILES CN(C)c1ccc(\C=C\c2cc(Br)cc(\C=C\c3ccc(cc3)N(C)C)c2)cc1 Show InChI InChI=1S/C26H27BrN2/c1-28(2)25-13-9-20(10-14-25)5-7-22-17-23(19-24(27)18-22)8-6-21-11-15-26(16-12-21)29(3)4/h5-19H,1-4H3/b7-5+,8-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477449
(CHEMBL248339)Show SMILES COc1cc(\C=C\c2cccc(\C=C\c3ccc(N4CCCC4)c(OC)c3)c2)ccc1N1CCCC1 Show InChI InChI=1S/C32H36N2O2/c1-35-31-23-27(14-16-29(31)33-18-3-4-19-33)12-10-25-8-7-9-26(22-25)11-13-28-15-17-30(32(24-28)36-2)34-20-5-6-21-34/h7-17,22-24H,3-6,18-21H2,1-2H3/b12-10+,13-11+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477442
(CHEMBL245476)Show SMILES COc1ccc(\C=C\c2cc(Br)cc(\C=C\c3ccc(OC)c(OC)c3)c2)cc1OC Show InChI InChI=1S/C26H25BrO4/c1-28-23-11-9-18(16-25(23)30-3)5-7-20-13-21(15-22(27)14-20)8-6-19-10-12-24(29-2)26(17-19)31-4/h5-17H,1-4H3/b7-5+,8-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | 2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |
Amyloid-beta precursor protein
(Homo sapiens (Human)) | BDBM50477427
(CHEMBL245479)Show SMILES CN(C)c1ccc(\C=C\c2cc(I)cc(\C=C\c3ccc(cc3)N(C)C)c2)cc1 Show InChI InChI=1S/C26H27IN2/c1-28(2)25-13-9-20(10-14-25)5-7-22-17-23(19-24(27)18-22)8-6-21-11-15-26(16-12-21)29(3)4/h5-19H,1-4H3/b7-5+,8-6+ | PDB MMDB
Reactome pathway KEGG
UniProtKB/SwissProt
B.MOAD DrugBank antibodypedia GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article PubMed
| n/a | n/a | >2.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Korea Institute of Science and Technology
Curated by ChEMBL
| Assay Description Inhibition of amyloid beta 42 fibril formation by thioflavin T assay |
Bioorg Med Chem Lett 17: 1466-70 (2007)
Article DOI: 10.1016/j.bmcl.2006.10.090 BindingDB Entry DOI: 10.7270/Q2PV6P4S |
More data for this Ligand-Target Pair | |