Found 65 hits Enz. Inhib. hit(s) with all data for entry = 50004440 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482966
(CHEMBL1270818)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(NC4CCN(CC4)S(C)(=O)=O)nc3-c12 Show InChI InChI=1S/C18H24N6O3S/c1-23-10-14(17(19)25)13-4-3-11-9-20-18(22-15(11)16(13)23)21-12-5-7-24(8-6-12)28(2,26)27/h9-10,12H,3-8H2,1-2H3,(H2,19,25)(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482947
(CHEMBL1270713)Show SMILES CCOC(=O)N1CCC(CC1)Nc1ncc2CCc3c(cn(C)c3-c2n1)C(N)=O Show InChI InChI=1S/C20H26N6O3/c1-3-29-20(28)26-8-6-13(7-9-26)23-19-22-10-12-4-5-14-15(18(21)27)11-25(2)17(14)16(12)24-19/h10-11,13H,3-9H2,1-2H3,(H2,21,27)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482978
(CHEMBL1271330)Show SMILES CN1CCN(CC1)c1cccc(Nc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)c1 Show InChI InChI=1S/C23H27N7O/c1-28-8-10-30(11-9-28)17-5-3-4-16(12-17)26-23-25-13-15-6-7-18-19(22(24)31)14-29(2)21(18)20(15)27-23/h3-5,12-14H,6-11H2,1-2H3,(H2,24,31)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482942
(CHEMBL1270419)Show SMILES CC(=O)N1CCC(CC1)Nc1ncc2CCc3c(cn(C)c3-c2n1)C(N)=O Show InChI InChI=1S/C19H24N6O2/c1-11(26)25-7-5-13(6-8-25)22-19-21-9-12-3-4-14-15(18(20)27)10-24(2)17(14)16(12)23-19/h9-10,13H,3-8H2,1-2H3,(H2,20,27)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482948
(CHEMBL1270920)Show SMILES CNC(=O)c1cn(C)c-2c1CCc1cnc(NC3CCN(CC3)S(C)(=O)=O)nc-21 Show InChI InChI=1S/C19H26N6O3S/c1-20-18(26)15-11-24(2)17-14(15)5-4-12-10-21-19(23-16(12)17)22-13-6-8-25(9-7-13)29(3,27)28/h10-11,13H,4-9H2,1-3H3,(H,20,26)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482968
(CHEMBL1271329)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)cc1 Show InChI InChI=1S/C23H27N7O/c1-28-9-11-30(12-10-28)17-6-4-16(5-7-17)26-23-25-13-15-3-8-18-19(22(24)31)14-29(2)21(18)20(15)27-23/h4-7,13-14H,3,8-12H2,1-2H3,(H2,24,31)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 2 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482944
(CHEMBL1270513)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(NC4CCN(CC4)C(=O)c4ccccc4)nc3-c12 Show InChI InChI=1S/C24H26N6O2/c1-29-14-19(22(25)31)18-8-7-16-13-26-24(28-20(16)21(18)29)27-17-9-11-30(12-10-17)23(32)15-5-3-2-4-6-15/h2-6,13-14,17H,7-12H2,1H3,(H2,25,31)(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482949
(CHEMBL1270921)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(NC4CCN(CC4)S(=O)(=O)c4ccccc4)nc3-c12 Show InChI InChI=1S/C23H26N6O3S/c1-28-14-19(22(24)30)18-8-7-15-13-25-23(27-20(15)21(18)28)26-16-9-11-29(12-10-16)33(31,32)17-5-3-2-4-6-17/h2-6,13-14,16H,7-12H2,1H3,(H2,24,30)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482987
(CHEMBL1271019)Show SMILES CNC(=O)c1cn(C)c-2c1CCc1cnc(NC3CCN(CC3)S(=O)(=O)c3ccccc3)nc-21 Show InChI InChI=1S/C24H28N6O3S/c1-25-23(31)20-15-29(2)22-19(20)9-8-16-14-26-24(28-21(16)22)27-17-10-12-30(13-11-17)34(32,33)18-6-4-3-5-7-18/h3-7,14-15,17H,8-13H2,1-2H3,(H,25,31)(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482940
(CHEMBL1270116)Show SMILES NC(=O)c1cn(c-2c1CCc1cnc(NC3CCCC3)nc-21)-c1ccc(cc1)S(N)(=O)=O Show InChI InChI=1S/C22H24N6O3S/c23-21(29)18-12-28(15-6-8-16(9-7-15)32(24,30)31)20-17(18)10-5-13-11-25-22(27-19(13)20)26-14-3-1-2-4-14/h6-9,11-12,14H,1-5,10H2,(H2,23,29)(H2,24,30,31)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482984
(CHEMBL1270223)Show SMILES NC(=O)c1cn(CC(F)(F)F)c-2c1CCc1cnc(NC3CCCC3)nc-21 Show InChI InChI=1S/C18H20F3N5O/c19-18(20,21)9-26-8-13(16(22)27)12-6-5-10-7-23-17(25-14(10)15(12)26)24-11-3-1-2-4-11/h7-8,11H,1-6,9H2,(H2,22,27)(H,23,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 5 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482939
(CHEMBL1270010)Show SMILES COc1ccc(cc1)-n1cc(C(N)=O)c2CCc3cnc(NC4CCCC4)nc3-c12 Show InChI InChI=1S/C23H25N5O2/c1-30-17-9-7-16(8-10-17)28-13-19(22(24)29)18-11-6-14-12-25-23(27-20(14)21(18)28)26-15-4-2-3-5-15/h7-10,12-13,15H,2-6,11H2,1H3,(H2,24,29)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482962
(CHEMBL1270224)Show SMILES CN1CCC(CC1)n1cc(C(N)=O)c2CCc3cnc(NC4CCCC4)nc3-c12 Show InChI InChI=1S/C22H30N6O/c1-27-10-8-16(9-11-27)28-13-18(21(23)29)17-7-6-14-12-24-22(26-19(14)20(17)28)25-15-4-2-3-5-15/h12-13,15-16H,2-11H2,1H3,(H2,23,29)(H,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482941
(CHEMBL1270319)Show SMILES CC(=O)N1CCC(CC1)n1cc(C(N)=O)c2CCc3cnc(NC4CCCC4)nc3-c12 Show InChI InChI=1S/C23H30N6O2/c1-14(30)28-10-8-17(9-11-28)29-13-19(22(24)31)18-7-6-15-12-25-23(27-20(15)21(18)29)26-16-4-2-3-5-16/h12-13,16-17H,2-11H2,1H3,(H2,24,31)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 7 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482973
(CHEMBL1270117)Show InChI InChI=1S/C18H23N5O2/c19-17(25)14-10-23(7-8-24)16-13(14)6-5-11-9-20-18(22-15(11)16)21-12-3-1-2-4-12/h9-10,12,24H,1-8H2,(H2,19,25)(H,20,21,22) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 8 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482945
(CHEMBL1270614)Show SMILES CN1CCN(CC1)C(=O)N1CCC(CC1)Nc1ncc2CCc3c(cn(C)c3-c2n1)C(N)=O Show InChI InChI=1S/C23H32N8O2/c1-28-9-11-31(12-10-28)23(33)30-7-5-16(6-8-30)26-22-25-13-15-3-4-17-18(21(24)32)14-29(2)20(17)19(15)27-22/h13-14,16H,3-12H2,1-2H3,(H2,24,32)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482988
(CHEMBL1270816)Show SMILES CC(=O)Nc1ccc(CNc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)cc1 Show InChI InChI=1S/C21H22N6O2/c1-12(28)25-15-6-3-13(4-7-15)9-23-21-24-10-14-5-8-16-17(20(22)29)11-27(2)19(16)18(14)26-21/h3-4,6-7,10-11H,5,8-9H2,1-2H3,(H2,22,29)(H,25,28)(H,23,24,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 13 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482951
(CHEMBL1271437)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(Nc4ccc(cc4)N4CCOCC4)nc3-c12 Show InChI InChI=1S/C22H24N6O2/c1-27-13-18(21(23)29)17-7-2-14-12-24-22(26-19(14)20(17)27)25-15-3-5-16(6-4-15)28-8-10-30-11-9-28/h3-6,12-13H,2,7-11H2,1H3,(H2,23,29)(H,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 14 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482952
(CHEMBL1269904)Show SMILES CN1CCN(CC1)c1ccc(Nc2ncc3CC(C)(C)c4c(cn(C)c4-c3n2)C(N)=O)cc1 Show InChI InChI=1S/C25H31N7O/c1-25(2)13-16-14-27-24(29-21(16)22-20(25)19(23(26)33)15-31(22)4)28-17-5-7-18(8-6-17)32-11-9-30(3)10-12-32/h5-8,14-15H,9-13H2,1-4H3,(H2,26,33)(H,27,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482970
(CHEMBL1271017)Show SMILES CN1CCN(CC1)c1ccc(CNc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)cc1 Show InChI InChI=1S/C24H29N7O/c1-29-9-11-31(12-10-29)18-6-3-16(4-7-18)13-26-24-27-14-17-5-8-19-20(23(25)32)15-30(2)22(19)21(17)28-24/h3-4,6-7,14-15H,5,8-13H2,1-2H3,(H2,25,32)(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482985
(CHEMBL1271020)Show InChI InChI=1S/C19H19N5O/c1-20-18(25)15-11-24(2)17-14(15)9-8-12-10-21-19(23-16(12)17)22-13-6-4-3-5-7-13/h3-7,10-11H,8-9H2,1-2H3,(H,20,25)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482933
(CHEMBL1271226)Show InChI InChI=1S/C14H17N5O2/c1-19-7-10(13(15)21)9-3-2-8-6-17-14(16-4-5-20)18-11(8)12(9)19/h6-7,20H,2-5H2,1H3,(H2,15,21)(H,16,17,18) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 19 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482989
(CHEMBL1269903)Show SMILES NC(=O)c1cn(c-2c1CCc1cnc(NC3CCCC3)nc-21)-c1ccccc1 Show InChI InChI=1S/C22H23N5O/c23-21(28)18-13-27(16-8-2-1-3-9-16)20-17(18)11-10-14-12-24-22(26-19(14)20)25-15-6-4-5-7-15/h1-3,8-9,12-13,15H,4-7,10-11H2,(H2,23,28)(H,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482932
(CHEMBL1271122)Show InChI InChI=1S/C18H18N6O/c1-24-10-14(17(19)25)13-5-4-12-9-22-18(23-15(12)16(13)24)21-8-11-3-2-6-20-7-11/h2-3,6-7,9-10H,4-5,8H2,1H3,(H2,19,25)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482931
(CHEMBL1271018)Show InChI InChI=1S/C18H18N6O/c1-24-10-14(17(19)25)13-3-2-12-9-22-18(23-15(12)16(13)24)21-8-11-4-6-20-7-5-11/h4-7,9-10H,2-3,8H2,1H3,(H2,19,25)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 21 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482937
(CHEMBL1269902)Show SMILES NC(=O)c1cn(Cc2ccccc2)c-2c1CCc1cnc(NC3CCCC3)nc-21 Show InChI InChI=1S/C23H25N5O/c24-22(29)19-14-28(13-15-6-2-1-3-7-15)21-18(19)11-10-16-12-25-23(27-20(16)21)26-17-8-4-5-9-17/h1-3,6-7,12,14,17H,4-5,8-11,13H2,(H2,24,29)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 23 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482981
(CHEMBL1271438)Show SMILES Cn1cc(C(N)=O)c2c1-c1nc(Nc3ccccc3)ncc1CC2(C)C Show InChI InChI=1S/C20H21N5O/c1-20(2)9-12-10-22-19(23-13-7-5-4-6-8-13)24-16(12)17-15(20)14(18(21)26)11-25(17)3/h4-8,10-11H,9H2,1-3H3,(H2,21,26)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 24 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482975
(CHEMBL1270613)Show SMILES CNC(=O)c1cn(C)c-2c1CCc1cnc(NC3CCN(CC3)C(=O)c3ccccc3)nc-21 Show InChI InChI=1S/C25H28N6O2/c1-26-23(32)20-15-30(2)22-19(20)9-8-17-14-27-25(29-21(17)22)28-18-10-12-31(13-11-18)24(33)16-6-4-3-5-7-16/h3-7,14-15,18H,8-13H2,1-2H3,(H,26,32)(H,27,28,29) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 25 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482959
(CHEMBL1270119)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(OC4CCN(C)CC4)cc3)nc-21 Show InChI InChI=1S/C27H34N6O2/c1-27(2)14-17-15-29-26(31-23(17)24-22(27)21(16-33(24)5)25(34)28-3)30-18-6-8-19(9-7-18)35-20-10-12-32(4)13-11-20/h6-9,15-16,20H,10-14H2,1-5H3,(H,28,34)(H,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 29 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482958
(CHEMBL1270011)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3cccc(c3)N3CCN(C)CC3)nc-21 Show InChI InChI=1S/C26H33N7O/c1-26(2)14-17-15-28-25(30-22(17)23-21(26)20(16-32(23)5)24(34)27-3)29-18-7-6-8-19(13-18)33-11-9-31(4)10-12-33/h6-8,13,15-16H,9-12,14H2,1-5H3,(H,27,34)(H,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 31 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482943
(CHEMBL1270512)Show SMILES CNC(=O)c1cn(C)c-2c1CCc1cnc(NC3CCN(CC3)C(C)=O)nc-21 Show InChI InChI=1S/C20H26N6O2/c1-12(27)26-8-6-14(7-9-26)23-20-22-10-13-4-5-15-16(19(28)21-2)11-25(3)18(15)17(13)24-20/h10-11,14H,4-9H2,1-3H3,(H,21,28)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 32 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482963
(CHEMBL1270515)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(CN(C)C)cc3)nc-21 Show InChI InChI=1S/C24H30N6O/c1-24(2)11-16-12-26-23(27-17-9-7-15(8-10-17)13-29(4)5)28-20(16)21-19(24)18(14-30(21)6)22(31)25-3/h7-10,12,14H,11,13H2,1-6H3,(H,25,31)(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482956
(CHEMBL1270321)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(CN4CCOCC4)cc3)nc-21 Show InChI InChI=1S/C26H32N6O2/c1-26(2)13-18-14-28-25(30-22(18)23-21(26)20(16-31(23)4)24(33)27-3)29-19-7-5-17(6-8-19)15-32-9-11-34-12-10-32/h5-8,14,16H,9-13,15H2,1-4H3,(H,27,33)(H,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 36 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482929
(CHEMBL1270918)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(NCc4ccc(cc4)S(C)(=O)=O)nc3-c12 Show InChI InChI=1S/C20H21N5O3S/c1-25-11-16(19(21)26)15-8-5-13-10-23-20(24-17(13)18(15)25)22-9-12-3-6-14(7-4-12)29(2,27)28/h3-4,6-7,10-11H,5,8-9H2,1-2H3,(H2,21,26)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482967
(CHEMBL1269905)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N3CCN(C)CC3)nc-21 Show InChI InChI=1S/C26H33N7O/c1-26(2)14-17-15-28-25(30-22(17)23-21(26)20(16-32(23)5)24(34)27-3)29-18-6-8-19(9-7-18)33-12-10-31(4)11-13-33/h6-9,15-16H,10-14H2,1-5H3,(H,27,34)(H,28,29,30) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 45 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482954
(CHEMBL1270225)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3cccc(OC4CCN(C)CC4)c3)nc-21 Show InChI InChI=1S/C27H34N6O2/c1-27(2)14-17-15-29-26(31-23(17)24-22(27)21(16-33(24)5)25(34)28-3)30-18-7-6-8-20(13-18)35-19-9-11-32(4)12-10-19/h6-8,13,15-16,19H,9-12,14H2,1-5H3,(H,28,34)(H,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 47 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482926
(CHEMBL1270612)Show InChI InChI=1S/C19H19N5O/c1-24-11-15(18(20)25)14-8-7-13-10-22-19(23-16(13)17(14)24)21-9-12-5-3-2-4-6-12/h2-6,10-11H,7-9H2,1H3,(H2,20,25)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 51 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482938
(CHEMBL1270009)Show SMILES NC(=O)c1cn(c-2c1CCc1cnc(NC3CCCC3)nc-21)-c1ccccn1 Show InChI InChI=1S/C21H22N6O/c22-20(28)16-12-27(17-7-3-4-10-23-17)19-15(16)9-8-13-11-24-21(26-18(13)19)25-14-5-1-2-6-14/h3-4,7,10-12,14H,1-2,5-6,8-9H2,(H2,22,28)(H,24,25,26) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482955
(CHEMBL1270226)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(CN4CCN(C)CC4)cc3)nc-21 Show InChI InChI=1S/C27H35N7O/c1-27(2)14-19-15-29-26(31-23(19)24-22(27)21(17-33(24)5)25(35)28-3)30-20-8-6-18(7-9-20)16-34-12-10-32(4)11-13-34/h6-9,15,17H,10-14,16H2,1-5H3,(H,28,35)(H,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 55 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482969
(CHEMBL1270711)Show SMILES COc1ccc(CNc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)cc1 Show InChI InChI=1S/C20H21N5O2/c1-25-11-16(19(21)26)15-8-5-13-10-23-20(24-17(13)18(15)25)22-9-12-3-6-14(27-2)7-4-12/h3-4,6-7,10-11H,5,8-9H2,1-2H3,(H2,21,26)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482976
(CHEMBL1270817)Show SMILES CCOC(=O)N1CCC(CC1)Nc1ncc2CCc3c(cn(C)c3-c2n1)C(=O)NC Show InChI InChI=1S/C21H28N6O3/c1-4-30-21(29)27-9-7-14(8-10-27)24-20-23-11-13-5-6-15-16(19(28)22-2)12-26(3)18(15)17(13)25-20/h11-12,14H,4-10H2,1-3H3,(H,22,28)(H,23,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482965
(CHEMBL1270318)Show SMILES CNC(=O)c1cn(C2CCN(C)CC2)c-2c1CCc1cnc(NC3CCCC3)nc-21 Show InChI InChI=1S/C23H32N6O/c1-24-22(30)19-14-29(17-9-11-28(2)12-10-17)21-18(19)8-7-15-13-25-23(27-20(15)21)26-16-5-3-4-6-16/h13-14,16-17H,3-12H2,1-2H3,(H,24,30)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482960
(CHEMBL1270320)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3cccc(CN4CCN(C)CC4)c3)nc-21 Show InChI InChI=1S/C27H35N7O/c1-27(2)14-19-15-29-26(31-23(19)24-22(27)21(17-33(24)5)25(35)28-3)30-20-8-6-7-18(13-20)16-34-11-9-32(4)10-12-34/h6-8,13,15,17H,9-12,14,16H2,1-5H3,(H,28,35)(H,29,30,31) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482982
(CHEMBL1270421)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3ccc(cc3)N(C)C)nc-21 Show InChI InChI=1S/C23H28N6O/c1-23(2)11-14-12-25-22(26-15-7-9-16(10-8-15)28(4)5)27-19(14)20-18(23)17(13-29(20)6)21(30)24-3/h7-10,12-13H,11H2,1-6H3,(H,24,30)(H,25,26,27) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 59 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482927
(CHEMBL1270710)Show SMILES COc1cccc(CNc2ncc3CCc4c(cn(C)c4-c3n2)C(N)=O)c1 Show InChI InChI=1S/C20H21N5O2/c1-25-11-16(19(21)26)15-7-6-13-10-23-20(24-17(13)18(15)25)22-9-12-4-3-5-14(8-12)27-2/h3-5,8,10-11H,6-7,9H2,1-2H3,(H2,21,26)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 66 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482957
(CHEMBL1271125)Show SMILES Cn1cc(C(=O)NCCO)c2CCc3cnc(Nc4ccccc4)nc3-c12 Show InChI InChI=1S/C20H21N5O2/c1-25-12-16(19(27)21-9-10-26)15-8-7-13-11-22-20(24-17(13)18(15)25)23-14-5-3-2-4-6-14/h2-6,11-12,26H,7-10H2,1H3,(H,21,27)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| KEGG
PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 74 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482928
(CHEMBL1270815)Show SMILES Cn1cc(C(N)=O)c2CCc3cnc(NCc4ccc(Br)cc4)nc3-c12 Show InChI InChI=1S/C19H18BrN5O/c1-25-10-15(18(21)26)14-7-4-12-9-23-19(24-16(12)17(14)25)22-8-11-2-5-13(20)6-3-11/h2-3,5-6,9-10H,4,7-8H2,1H3,(H2,21,26)(H,22,23,24) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482977
(CHEMBL1271124)Show SMILES Cn1cc(C(=O)NC2CC2)c2CCc3cnc(Nc4ccccc4)nc3-c12 Show InChI InChI=1S/C21H21N5O/c1-26-12-17(20(27)23-15-8-9-15)16-10-7-13-11-22-21(25-18(13)19(16)26)24-14-5-3-2-4-6-14/h2-6,11-12,15H,7-10H2,1H3,(H,23,27)(H,22,24,25) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 81 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482961
(CHEMBL1270615)Show SMILES CNC(=O)c1cn(C)c-2c1C(C)(C)Cc1cnc(Nc3cccc(CN(C)C)c3)nc-21 Show InChI InChI=1S/C24H30N6O/c1-24(2)11-16-12-26-23(27-17-9-7-8-15(10-17)13-29(4)5)28-20(16)21-19(24)18(14-30(21)6)22(31)25-3/h7-10,12,14H,11,13H2,1-6H3,(H,25,31)(H,26,27,28) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 83 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Cyclin-A1/Cyclin-A2/Cyclin-dependent kinase 2
(Homo sapiens (Human)) | BDBM50482971
(CHEMBL1271123)Show InChI InChI=1S/C18H18N6O/c1-24-10-14(17(19)25)13-6-5-11-8-21-18(23-15(11)16(13)24)22-9-12-4-2-3-7-20-12/h2-4,7-8,10H,5-6,9H2,1H3,(H2,19,25)(H,21,22,23) | PDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
antibodypedia
antibodypedia
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 87 | n/a | n/a | n/a | n/a | n/a | n/a |
Jinan University
Curated by ChEMBL
| Assay Description
Inhibition of CDK2/cyclin A |
Bioorg Med Chem Lett 20: 6764-72 (2010)
Article DOI: 10.1016/j.bmcl.2010.08.131
BindingDB Entry DOI: 10.7270/Q2X069V6 |
More data for this
Ligand-Target Pair | |
Search and Browse
