Found 41 hits Enz. Inhib. hit(s) with all data for entry = 50004667 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kJ/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485379
(CHEMBL2059641)Show SMILES CNc1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)cc1 Show InChI InChI=1S/C27H32ClN5O4S/c1-27(10-11-27)19-37-25-24(17-30-33(26(25)34)23-5-3-4-21(28)16-23)31-12-14-32(15-13-31)38(35,36)18-20-6-8-22(29-2)9-7-20/h3-9,16-17,29H,10-15,18-19H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 17.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485394
(CHEMBL2059493)Show SMILES CC1(COc2c(cnn(-c3cc(F)cc(F)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)c(F)c2)CC1 Show InChI InChI=1S/C26H28F3N5O4S/c1-26(4-5-26)16-38-24-23(14-31-34(25(24)35)20-12-18(27)11-19(28)13-20)32-6-8-33(9-7-32)39(36,37)15-17-2-3-22(30)21(29)10-17/h2-3,10-14H,4-9,15-16,30H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 53.2 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485364
(CHEMBL2059474)Show SMILES FCC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccccc2)CC1 Show InChI InChI=1S/C26H28ClFN4O4S/c27-21-7-4-8-22(15-21)32-25(33)24(36-19-26(18-28)9-10-26)23(16-29-32)30-11-13-31(14-12-30)37(34,35)17-20-5-2-1-3-6-20/h1-8,15-16H,9-14,17-19H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 54.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485398
(CHEMBL2059384)Show SMILES Fc1cc(F)cc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCCC2)c1=O Show InChI InChI=1S/C26H28F2N4O4S/c27-20-14-21(28)16-22(15-20)32-26(33)25(36-23-8-4-5-9-23)24(17-29-32)30-10-12-31(13-11-30)37(34,35)18-19-6-2-1-3-7-19/h1-3,6-7,14-17,23H,4-5,8-13,18H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 56.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485363
(CHEMBL2059473)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccccc2)CC1 Show InChI InChI=1S/C26H29ClN4O4S/c1-26(10-11-26)19-35-24-23(17-28-31(25(24)32)22-9-5-8-21(27)16-22)29-12-14-30(15-13-29)36(33,34)18-20-6-3-2-4-7-20/h2-9,16-17H,10-15,18-19H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 56.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485376
(CHEMBL2059494)Show SMILES CC1(COc2c(cnn(-c3cc(F)cc(F)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)c(Cl)c2)CC1 Show InChI InChI=1S/C26H28ClF2N5O4S/c1-26(4-5-26)16-38-24-23(14-31-34(25(24)35)20-12-18(28)11-19(29)13-20)32-6-8-33(9-7-32)39(36,37)15-17-2-3-22(30)21(27)10-17/h2-3,10-14H,4-9,15-16,30H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 69 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485368
(CHEMBL2059481)Show SMILES Fc1cccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cc(F)cc(F)c3)c(=O)c2OC2CCCC2)c1 Show InChI InChI=1S/C26H27F3N4O4S/c27-19-5-3-4-18(12-19)17-38(35,36)32-10-8-31(9-11-32)24-16-30-33(22-14-20(28)13-21(29)15-22)26(34)25(24)37-23-6-1-2-7-23/h3-5,12-16,23H,1-2,6-11,17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 72.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485390
(CHEMBL2059482)Show SMILES Fc1ccccc1CS(=O)(=O)N1CCN(CC1)c1cnn(-c2cccc(Cl)c2)c(=O)c1OC1CCCC1 Show InChI InChI=1S/C26H28ClFN4O4S/c27-20-7-5-8-21(16-20)32-26(33)25(36-22-9-2-3-10-22)24(17-29-32)30-12-14-31(15-13-30)37(34,35)18-19-6-1-4-11-23(19)28/h1,4-8,11,16-17,22H,2-3,9-10,12-15,18H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 73.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485375
(CHEMBL2059492)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2cccc(N)c2)CC1 Show InChI InChI=1S/C26H30ClN5O4S/c1-26(8-9-26)18-36-24-23(16-29-32(25(24)33)22-7-3-5-20(27)15-22)30-10-12-31(13-11-30)37(34,35)17-19-4-2-6-21(28)14-19/h2-7,14-16H,8-13,17-18,28H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 73.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485380
(CHEMBL2059642)Show SMILES CN(C)c1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)cc1 Show InChI InChI=1S/C28H34ClN5O4S/c1-28(11-12-28)20-38-26-25(18-30-34(27(26)35)24-6-4-5-22(29)17-24)32-13-15-33(16-14-32)39(36,37)19-21-7-9-23(10-8-21)31(2)3/h4-10,17-18H,11-16,19-20H2,1-3H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 87.4 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485393
(CHEMBL2059490)Show SMILES Oc1cccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cc(F)cc(F)c3)c(=O)c2OC2CCCC2)c1 Show InChI InChI=1S/C26H28F2N4O5S/c27-19-13-20(28)15-21(14-19)32-26(34)25(37-23-6-1-2-7-23)24(16-29-32)30-8-10-31(11-9-30)38(35,36)17-18-4-3-5-22(33)12-18/h3-5,12-16,23,33H,1-2,6-11,17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 91.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485396
(CHEMBL2059643)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)nc2)CC1 Show InChI InChI=1S/C25H29ClN6O4S/c1-25(7-8-25)17-36-23-21(15-29-32(24(23)33)20-4-2-3-19(26)13-20)30-9-11-31(12-10-30)37(34,35)16-18-5-6-22(27)28-14-18/h2-6,13-15H,7-12,16-17H2,1H3,(H2,27,28) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 91.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485392
(CHEMBL1770665)Show SMILES Nc1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)cc1 Show InChI InChI=1S/C26H30ClN5O4S/c27-20-4-3-5-22(16-20)32-26(33)25(36-23-6-1-2-7-23)24(17-29-32)30-12-14-31(15-13-30)37(34,35)18-19-8-10-21(28)11-9-19/h3-5,8-11,16-17,23H,1-2,6-7,12-15,18,28H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 91.9 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485400
(CHEMBL2059496)Show SMILES COc1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)ccc1N Show InChI InChI=1S/C27H32ClN5O5S/c1-27(8-9-27)18-38-25-23(16-30-33(26(25)34)21-5-3-4-20(28)15-21)31-10-12-32(13-11-31)39(35,36)17-19-6-7-22(29)24(14-19)37-2/h3-7,14-16H,8-13,17-18,29H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 104 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485372
(CHEMBL2059488)Show SMILES Nc1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cc(F)cc(F)c3)c(=O)c2OC2CCCC2)cc1 Show InChI InChI=1S/C26H29F2N5O4S/c27-19-13-20(28)15-22(14-19)33-26(34)25(37-23-3-1-2-4-23)24(16-30-33)31-9-11-32(12-10-31)38(35,36)17-18-5-7-21(29)8-6-18/h5-8,13-16,23H,1-4,9-12,17,29H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485367
(CHEMBL1770516)Show SMILES Fc1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)cc1 Show InChI InChI=1S/C26H28ClFN4O4S/c27-20-4-3-5-22(16-20)32-26(33)25(36-23-6-1-2-7-23)24(17-29-32)30-12-14-31(15-13-30)37(34,35)18-19-8-10-21(28)11-9-19/h3-5,8-11,16-17,23H,1-2,6-7,12-15,18H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 109 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485374
(CHEMBL2059491)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)cc2)CC1 Show InChI InChI=1S/C26H30ClN5O4S/c1-26(9-10-26)18-36-24-23(16-29-32(25(24)33)22-4-2-3-20(27)15-22)30-11-13-31(14-12-30)37(34,35)17-19-5-7-21(28)8-6-19/h2-8,15-16H,9-14,17-18,28H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 110 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485397
(CHEMBL2059637)Show SMILES Cc1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cc(F)cc(F)c3)c(=O)c2OCC2(C)CC2)ccc1N Show InChI InChI=1S/C27H31F2N5O4S/c1-18-11-19(3-4-23(18)30)16-39(36,37)33-9-7-32(8-10-33)24-15-31-34(22-13-20(28)12-21(29)14-22)26(35)25(24)38-17-27(2)5-6-27/h3-4,11-15H,5-10,16-17,30H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 125 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485373
(CHEMBL2059489)Show SMILES Nc1cccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cc(F)cc(F)c3)c(=O)c2OC2CCCC2)c1 Show InChI InChI=1S/C26H29F2N5O4S/c27-19-13-20(28)15-22(14-19)33-26(34)25(37-23-6-1-2-7-23)24(16-30-33)31-8-10-32(11-9-31)38(35,36)17-18-4-3-5-21(29)12-18/h3-5,12-16,23H,1-2,6-11,17,29H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 128 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485399
(CHEMBL2059483)Show SMILES Clc1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)cc1 Show InChI InChI=1S/C26H28Cl2N4O4S/c27-20-10-8-19(9-11-20)18-37(34,35)31-14-12-30(13-15-31)24-17-29-32(22-5-3-4-21(28)16-22)26(33)25(24)36-23-6-1-2-7-23/h3-5,8-11,16-17,23H,1-2,6-7,12-15,18H2 | UniProtKB/TrEMBL
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| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 141 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485395
(CHEMBL2059497)Show SMILES Cc1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)ccc1N Show InChI InChI=1S/C27H32ClN5O4S/c1-19-14-20(6-7-23(19)29)17-38(35,36)32-12-10-31(11-13-32)24-16-30-33(22-5-3-4-21(28)15-22)26(34)25(24)37-18-27(2)8-9-27/h3-7,14-16H,8-13,17-18,29H2,1-2H3 | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 143 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485369
(CHEMBL2059484)Show SMILES Clc1cccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)c1 Show InChI InChI=1S/C26H28Cl2N4O4S/c27-20-6-3-5-19(15-20)18-37(34,35)31-13-11-30(12-14-31)24-17-29-32(22-8-4-7-21(28)16-22)26(33)25(24)36-23-9-1-2-10-23/h3-8,15-17,23H,1-2,9-14,18H2 | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 159 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485381
(CHEMBL2059644)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2cccnc2N)CC1 Show InChI InChI=1S/C25H29ClN6O4S/c1-25(7-8-25)17-36-22-21(15-29-32(24(22)33)20-6-2-5-19(26)14-20)30-10-12-31(13-11-30)37(34,35)16-18-4-3-9-28-23(18)27/h2-6,9,14-15H,7-8,10-13,16-17H2,1H3,(H2,27,28) | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 238 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485386
(CHEMBL2059645)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccnc(N)c2)CC1 Show InChI InChI=1S/C25H29ClN6O4S/c1-25(6-7-25)17-36-23-21(15-29-32(24(23)33)20-4-2-3-19(26)14-20)30-9-11-31(12-10-30)37(34,35)16-18-5-8-28-22(27)13-18/h2-5,8,13-15H,6-7,9-12,16-17H2,1H3,(H2,27,28) | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 275 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485377
(CHEMBL2059638)Show SMILES CCc1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)ccc1N Show InChI InChI=1S/C28H34ClN5O4S/c1-3-21-15-20(7-8-24(21)30)18-39(36,37)33-13-11-32(12-14-33)25-17-31-34(23-6-4-5-22(29)16-23)27(35)26(25)38-19-28(2)9-10-28/h4-8,15-17H,3,9-14,18-19,30H2,1-2H3 | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 314 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485391
(CHEMBL2059485)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2cc(Cl)cc(Cl)c2)c(OC2CCCC2)c1=O Show InChI InChI=1S/C26H27Cl3N4O4S/c27-19-4-3-5-22(15-19)33-26(34)25(37-23-6-1-2-7-23)24(16-30-33)31-8-10-32(11-9-31)38(35,36)17-18-12-20(28)14-21(29)13-18/h3-5,12-16,23H,1-2,6-11,17H2 | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 351 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50483790
(CHEMBL1770510)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCCC2)c1=O Show InChI InChI=1S/C26H29ClN4O4S/c27-21-9-6-10-22(17-21)31-26(32)25(35-23-11-4-5-12-23)24(18-28-31)29-13-15-30(16-14-29)36(33,34)19-20-7-2-1-3-8-20/h1-3,6-10,17-18,23H,4-5,11-16,19H2 | UniProtKB/TrEMBL
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AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 378 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485401
(CHEMBL2059640)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)c(c2)C(N)=O)CC1 Show InChI InChI=1S/C27H31ClN6O5S/c1-27(7-8-27)17-39-24-23(15-31-34(26(24)36)20-4-2-3-19(28)14-20)32-9-11-33(12-10-32)40(37,38)16-18-5-6-22(29)21(13-18)25(30)35/h2-6,13-15H,7-12,16-17,29H2,1H3,(H2,30,35) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 510 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485371
(CHEMBL2059487)Show SMILES Fc1cc(F)cc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccncc2)c(OC2CCCC2)c1=O Show InChI InChI=1S/C25H27F2N5O4S/c26-19-13-20(27)15-21(14-19)32-25(33)24(36-22-3-1-2-4-22)23(16-29-32)30-9-11-31(12-10-30)37(34,35)17-18-5-7-28-8-6-18/h5-8,13-16,22H,1-4,9-12,17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 564 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485383
(CHEMBL2059477)Show SMILES CC(C)(O)CCOc1c(cnn(-c2cc(F)cc(F)c2)c1=O)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H30F2N4O5S/c1-26(2,34)8-13-37-24-23(17-29-32(25(24)33)22-15-20(27)14-21(28)16-22)30-9-11-31(12-10-30)38(35,36)18-19-6-4-3-5-7-19/h3-7,14-17,34H,8-13,18H2,1-2H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 565 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485378
(CHEMBL2059639)Show SMILES CC(C)c1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OCC2(C)CC2)ccc1N Show InChI InChI=1S/C29H36ClN5O4S/c1-20(2)24-15-21(7-8-25(24)31)18-40(37,38)34-13-11-33(12-14-34)26-17-32-35(23-6-4-5-22(30)16-23)28(36)27(26)39-19-29(3)9-10-29/h4-8,15-17,20H,9-14,18-19,31H2,1-3H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 631 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485385
(CHEMBL2059495)Show SMILES CC1(COc2c(cnn(-c3cccc(Cl)c3)c2=O)N2CCN(CC2)S(=O)(=O)Cc2ccc(N)c(c2)C(F)(F)F)CC1 Show InChI InChI=1S/C27H29ClF3N5O4S/c1-26(7-8-26)17-40-24-23(15-33-36(25(24)37)20-4-2-3-19(28)14-20)34-9-11-35(12-10-34)41(38,39)16-18-5-6-22(32)21(13-18)27(29,30)31/h2-6,13-15H,7-12,16-17,32H2,1H3 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 637 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485388
(CHEMBL2059475)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCOCC2)c1=O Show InChI InChI=1S/C26H29ClN4O5S/c27-21-7-4-8-22(17-21)31-26(32)25(36-23-9-15-35-16-10-23)24(18-28-31)29-11-13-30(14-12-29)37(33,34)19-20-5-2-1-3-6-20/h1-8,17-18,23H,9-16,19H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 917 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485389
(CHEMBL2059480)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OCCc2ccccn2)c1=O Show InChI InChI=1S/C28H28ClN5O4S/c29-23-9-6-11-25(19-23)34-28(35)27(38-18-12-24-10-4-5-13-30-24)26(20-31-34)32-14-16-33(17-15-32)39(36,37)21-22-7-2-1-3-8-22/h1-11,13,19-20H,12,14-18,21H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.05E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485382
(CHEMBL2059479)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCc3cccnc23)c1=O Show InChI InChI=1S/C29H28ClN5O4S/c30-23-9-4-10-24(18-23)35-29(36)28(39-26-12-11-22-8-5-13-31-27(22)26)25(19-32-35)33-14-16-34(17-15-33)40(37,38)20-21-6-2-1-3-7-21/h1-10,13,18-19,26H,11-12,14-17,20H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.38E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485387
(CHEMBL2059385)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCCCC2)c1=O Show InChI InChI=1S/C27H31ClN4O4S/c28-22-10-7-11-23(18-22)32-27(33)26(36-24-12-5-2-6-13-24)25(19-29-32)30-14-16-31(17-15-30)37(34,35)20-21-8-3-1-4-9-21/h1,3-4,7-11,18-19,24H,2,5-6,12-17,20H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.47E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485365
(CHEMBL2059476)Show SMILES OC1CCC(C1)Oc1c(cnn(-c2cccc(Cl)c2)c1=O)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C26H29ClN4O5S/c27-20-7-4-8-21(15-20)31-26(33)25(36-23-10-9-22(32)16-23)24(17-28-31)29-11-13-30(14-12-29)37(34,35)18-19-5-2-1-3-6-19/h1-8,15,17,22-23,32H,9-14,16,18H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 1.65E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485384
(CHEMBL1770660)Show SMILES OC(=O)c1ccc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)cc1 Show InChI InChI=1S/C27H29ClN4O6S/c28-21-4-3-5-22(16-21)32-26(33)25(38-23-6-1-2-7-23)24(17-29-32)30-12-14-31(15-13-30)39(36,37)18-19-8-10-20(11-9-19)27(34)35/h3-5,8-11,16-17,23H,1-2,6-7,12-15,18H2,(H,34,35) | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 4.18E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485366
(CHEMBL2059478)Show SMILES Clc1cccc(c1)-n1ncc(N2CCN(CC2)S(=O)(=O)Cc2ccccc2)c(OC2CCCc3ncccc23)c1=O Show InChI InChI=1S/C30H30ClN5O4S/c31-23-9-4-10-24(19-23)36-30(37)29(40-28-13-5-12-26-25(28)11-6-14-32-26)27(20-33-36)34-15-17-35(18-16-34)41(38,39)21-22-7-2-1-3-8-22/h1-4,6-11,14,19-20,28H,5,12-13,15-18,21H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 6.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50483465
(CHEMBL1684737)Show SMILES O=c1c(N2CCOCC2)c(cnn1-c1ccccc1)N1CCN(CC1)S(=O)(=O)Cc1ccccc1 Show InChI InChI=1S/C25H29N5O4S/c31-25-24(28-15-17-34-18-16-28)23(19-26-30(25)22-9-5-2-6-10-22)27-11-13-29(14-12-27)35(32,33)20-21-7-3-1-4-8-21/h1-10,19H,11-18,20H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | 9.28E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
1,3-beta-D-glucan synthase catalytic subunit
(Candida albicans) | BDBM50485370
(CHEMBL2059486)Show SMILES FC(F)(F)c1cc(CS(=O)(=O)N2CCN(CC2)c2cnn(-c3cccc(Cl)c3)c(=O)c2OC2CCCC2)cc(c1)C(F)(F)F Show InChI InChI=1S/C28H27ClF6N4O4S/c29-21-4-3-5-22(15-21)39-26(40)25(43-23-6-1-2-7-23)24(16-36-39)37-8-10-38(11-9-37)44(41,42)17-18-12-19(27(30,31)32)14-20(13-18)28(33,34)35/h3-5,12-16,23H,1-2,6-11,17H2 | UniProtKB/TrEMBL
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| Article
PubMed
| n/a | n/a | >2.25E+5 | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Research Laboratories
Curated by ChEMBL
| Assay Description
Inhibition of 1,3-beta-D-glucan synthase in Candida albicans BWP17 membranes |
Bioorg Med Chem Lett 22: 5268-71 (2012)
Article DOI: 10.1016/j.bmcl.2012.06.091
BindingDB Entry DOI: 10.7270/Q2MC92WW |
More data for this
Ligand-Target Pair | |
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