Found 100 hits Enz. Inhib. hit(s) with all data for entry = 50004899 Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030692
(CHEMBL339672 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C35H32Cl2FN5O5S/c1-3-5-14-32-40-43(30-20-24(17-18-28(30)37)39-33(44)4-2)35(46)42(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-27(26)36/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.0720 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030692
(CHEMBL339672 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C35H32Cl2FN5O5S/c1-3-5-14-32-40-43(30-20-24(17-18-28(30)37)39-33(44)4-2)35(46)42(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-27(26)36/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.0721 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030684
(CHEMBL339722 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O7S/c1-6-8-13-30-38-41(28-19-24(16-17-26(28)35)37-31(42)21-47-7-2)33(44)40(30)20-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)49(45,46)39-32(43)48-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030684
(CHEMBL339722 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)COCC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O7S/c1-6-8-13-30-38-41(28-19-24(16-17-26(28)35)37-31(42)21-47-7-2)33(44)40(30)20-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)49(45,46)39-32(43)48-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030729
(CHEMBL124771 | N-{4-Bromo-3-[3-butyl-4-(3-fluoro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030729
(CHEMBL124771 | N-{4-Bromo-3-[3-butyl-4-(3-fluoro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.120 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030687
(CHEMBL339256 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C36H32ClF4N5O5S/c1-3-5-14-32-43-46(30-20-24(42-33(47)4-2)17-18-27(30)36(39,40)41)35(49)45(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)52(50,51)44-34(48)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,42,47)(H,44,48) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030718
(CHEMBL332576 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCC Show InChI InChI=1S/C32H33F4N5O6S/c1-4-7-12-28-38-41(26-18-22(37-29(42)5-2)15-16-24(26)32(34,35)36)31(44)40(28)19-21-14-13-20(17-25(21)33)23-10-8-9-11-27(23)48(45,46)39-30(43)47-6-3/h8-11,13-18H,4-7,12,19H2,1-3H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030728
(CHEMBL339605 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-t-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37ClFN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030687
(CHEMBL339256 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C36H32ClF4N5O5S/c1-3-5-14-32-43-46(30-20-24(42-33(47)4-2)17-18-27(30)36(39,40)41)35(49)45(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)52(50,51)44-34(48)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,42,47)(H,44,48) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030728
(CHEMBL339605 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-t-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37ClFN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030718
(CHEMBL332576 | N-{3-[3-Butyl-4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OCC Show InChI InChI=1S/C32H33F4N5O6S/c1-4-7-12-28-38-41(26-18-22(37-29(42)5-2)15-16-24(26)32(34,35)36)31(44)40(28)19-21-14-13-20(17-25(21)33)23-10-8-9-11-27(23)48(45,46)39-30(43)47-6-3/h8-11,13-18H,4-7,12,19H2,1-3H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.130 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030710
(CHEMBL332909 | N-{3-[4-(2'-Benzoylsulfamoyl-3-fluo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C36H33F4N5O5S/c1-3-5-15-32-42-45(30-21-26(41-33(46)4-2)18-19-28(30)36(38,39)40)35(48)44(32)22-25-17-16-24(20-29(25)37)27-13-9-10-14-31(27)51(49,50)43-34(47)23-11-7-6-8-12-23/h6-14,16-21H,3-5,15,22H2,1-2H3,(H,41,46)(H,43,47) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030698
(CHEMBL435811 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-t-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O7S/c1-6-7-12-30-38-41(28-20-24(15-16-26(28)35)37-31(42)17-18-47-5)33(44)40(30)21-23-14-13-22(19-27(23)36)25-10-8-9-11-29(25)49(45,46)39-32(43)48-34(2,3)4/h8-11,13-16,19-20H,6-7,12,17-18,21H2,1-5H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030731
(CHEMBL338101 | N-Butyl-3-{3-butyl-4-[2'-(2-chloro-...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)c1=O Show InChI InChI=1S/C37H37Cl2N5O5S/c1-3-5-15-34-41-44(32-23-27(20-21-31(32)39)35(45)40-22-6-4-2)37(47)43(34)24-25-16-18-26(19-17-25)28-11-8-10-14-33(28)50(48,49)42-36(46)29-12-7-9-13-30(29)38/h7-14,16-21,23H,3-6,15,22,24H2,1-2H3,(H,40,45)(H,42,46) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030698
(CHEMBL435811 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-t-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CCOC)ccc2Cl)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H39ClFN5O7S/c1-6-7-12-30-38-41(28-20-24(15-16-26(28)35)37-31(42)17-18-47-5)33(44)40(30)21-23-14-13-22(19-27(23)36)25-10-8-9-11-29(25)49(45,46)39-32(43)48-34(2,3)4/h8-11,13-16,19-20H,6-7,12,17-18,21H2,1-5H3,(H,37,42)(H,39,43) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030731
(CHEMBL338101 | N-Butyl-3-{3-butyl-4-[2'-(2-chloro-...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)c1=O Show InChI InChI=1S/C37H37Cl2N5O5S/c1-3-5-15-34-41-44(32-23-27(20-21-31(32)39)35(45)40-22-6-4-2)37(47)43(34)24-25-16-18-26(19-17-25)28-11-8-10-14-33(28)50(48,49)42-36(46)29-12-7-9-13-30(29)38/h7-14,16-21,23H,3-6,15,22,24H2,1-2H3,(H,40,45)(H,42,46) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030710
(CHEMBL332909 | N-{3-[4-(2'-Benzoylsulfamoyl-3-fluo...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1 Show InChI InChI=1S/C36H33F4N5O5S/c1-3-5-15-32-42-45(30-21-26(41-33(46)4-2)18-19-28(30)36(38,39)40)35(48)44(32)22-25-17-16-24(20-29(25)37)27-13-9-10-14-31(27)51(49,50)43-34(47)23-11-7-6-8-12-23/h6-14,16-21H,3-5,15,22H2,1-2H3,(H,41,46)(H,43,47) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.140 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030697
(CHEMBL339004 | N-Butyl-3-{3-butyl-4-[2'-(2-chloro-...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)c1=O Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-3-5-15-34-42-45(32-22-25(18-19-30(32)39)35(46)41-20-6-4-2)37(48)44(34)23-26-17-16-24(21-31(26)40)27-11-8-10-14-33(27)51(49,50)43-36(47)28-12-7-9-13-29(28)38/h7-14,16-19,21-22H,3-6,15,20,23H2,1-2H3,(H,41,46)(H,43,47) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030711
(CHEMBL338027 | L-163958 | Pentanoic acid {4-bromo-...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-30(41)36-23-16-17-25(34)27(19-23)40-32(43)39(29(7-2)37-40)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030711
(CHEMBL338027 | L-163958 | Pentanoic acid {4-bromo-...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C33H37BrFN5O6S/c1-6-8-13-30(41)36-23-16-17-25(34)27(19-23)40-32(43)39(29(7-2)37-40)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
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Similars
| Article
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030697
(CHEMBL339004 | N-Butyl-3-{3-butyl-4-[2'-(2-chloro-...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2Cl)c1=O Show InChI InChI=1S/C37H36Cl2FN5O5S/c1-3-5-15-34-42-45(32-22-25(18-19-30(32)39)35(46)41-20-6-4-2)37(48)44(34)23-26-17-16-24(21-31(26)40)27-11-8-10-14-33(27)51(49,50)43-36(47)28-12-7-9-13-29(28)38/h7-14,16-19,21-22H,3-6,15,20,23H2,1-2H3,(H,41,46)(H,43,47) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.160 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030695
(CHEMBL340632 | N-Butyl-3-[3-butyl-4-(3-fluoro-2'-(...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C35H41ClFN5O6S/c1-6-8-14-31-39-42(29-21-24(17-18-27(29)36)32(43)38-19-9-7-2)34(45)41(31)22-25-16-15-23(20-28(25)37)26-12-10-11-13-30(26)49(46,47)40-33(44)48-35(3,4)5/h10-13,15-18,20-21H,6-9,14,19,22H2,1-5H3,(H,38,43)(H,40,44) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030714
(CHEMBL93907 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzoy...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C35H33Cl2N5O5S/c1-3-5-14-32-39-42(30-21-25(19-20-29(30)37)38-33(43)4-2)35(45)41(32)22-23-15-17-24(18-16-23)26-10-7-9-13-31(26)48(46,47)40-34(44)27-11-6-8-12-28(27)36/h6-13,15-21H,3-5,14,22H2,1-2H3,(H,38,43)(H,40,44) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030714
(CHEMBL93907 | N-(3-{3-Butyl-4-[2'-(2-chloro-benzoy...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1Cl Show InChI InChI=1S/C35H33Cl2N5O5S/c1-3-5-14-32-39-42(30-21-25(19-20-29(30)37)38-33(43)4-2)35(45)41(32)22-23-15-17-24(18-16-23)26-10-7-9-13-31(26)48(46,47)40-34(44)27-11-6-8-12-28(27)36/h6-13,15-21H,3-5,14,22H2,1-2H3,(H,38,43)(H,40,44) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.170 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030695
(CHEMBL340632 | N-Butyl-3-[3-butyl-4-(3-fluoro-2'-(...)Show SMILES CCCCNC(=O)c1ccc(Cl)c(c1)-n1nc(CCCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C35H41ClFN5O6S/c1-6-8-14-31-39-42(29-21-24(17-18-27(29)36)32(43)38-19-9-7-2)34(45)41(31)22-25-16-15-23(20-28(25)37)26-12-10-11-13-30(26)49(46,47)40-33(44)48-35(3,4)5/h10-13,15-18,20-21H,6-9,14,19,22H2,1-5H3,(H,38,43)(H,40,44) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.178 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030689
(CHEMBL125008 | N-{4-Bromo-3-[3-butyl-4-(3-fluoro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C37H37BrFN5O6S/c1-5-6-16-33-41-44(31-22-27(19-20-29(31)38)40-34(45)24-12-8-7-9-13-24)36(47)43(33)23-26-18-17-25(21-30(26)39)28-14-10-11-15-32(28)51(48,49)42-35(46)50-37(2,3)4/h7-15,17-22H,5-6,16,23H2,1-4H3,(H,40,45)(H,42,46) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50486804
(CHEMBL2236976)Show SMILES CCCCC(=O)Nc1ccc(Cl)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(Cl)ccc2Cl)c1=O Show InChI InChI=1S/C36H33Cl3FN5O5S/c1-3-5-11-34(46)41-25-15-17-29(39)31(20-25)45-36(48)44(33(42-45)8-4-2)21-23-13-12-22(18-30(23)40)26-9-6-7-10-32(26)51(49,50)43-35(47)27-19-24(37)14-16-28(27)38/h6-7,9-10,12-20H,3-5,8,11,21H2,1-2H3,(H,41,46)(H,43,47) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030689
(CHEMBL125008 | N-{4-Bromo-3-[3-butyl-4-(3-fluoro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C37H37BrFN5O6S/c1-5-6-16-33-41-44(31-22-27(19-20-29(31)38)40-34(45)24-12-8-7-9-13-24)36(47)43(33)23-26-18-17-25(21-30(26)39)28-14-10-11-15-32(28)51(48,49)42-35(46)50-37(2,3)4/h7-15,17-22H,5-6,16,23H2,1-4H3,(H,40,45)(H,42,46) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50486804
(CHEMBL2236976)Show SMILES CCCCC(=O)Nc1ccc(Cl)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(Cl)ccc2Cl)c1=O Show InChI InChI=1S/C36H33Cl3FN5O5S/c1-3-5-11-34(46)41-25-15-17-29(39)31(20-25)45-36(48)44(33(42-45)8-4-2)21-23-13-12-22(18-30(23)40)26-9-6-7-10-32(26)51(49,50)43-35(47)27-19-24(37)14-16-28(27)38/h6-7,9-10,12-20H,3-5,8,11,21H2,1-2H3,(H,41,46)(H,43,47) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| PC cid PC sid UniChem
| Article
| n/a | n/a | 0.190 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030712
(2-Ethoxy-N-{3-[4-(3-fluoro-2'-(N-t-butyloxycarbony...)Show SMILES CCCc1nn(-c2cc(NC(=O)COCC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H37F4N5O7S/c1-6-10-29-40-43(27-18-23(39-30(44)20-49-7-2)15-16-25(27)34(36,37)38)32(46)42(29)19-22-14-13-21(17-26(22)35)24-11-8-9-12-28(24)51(47,48)41-31(45)50-33(3,4)5/h8-9,11-18H,6-7,10,19-20H2,1-5H3,(H,39,44)(H,41,45) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030688
(CHEMBL122917 | N-(3-{3-Butyl-4-[2'-(3,3-dimethyl-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)CC(C)(C)C Show InChI InChI=1S/C35H39F4N5O5S/c1-6-8-13-30-41-44(28-19-24(40-31(45)7-2)16-17-26(28)35(37,38)39)33(47)43(30)21-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)50(48,49)42-32(46)20-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,40,45)(H,42,46) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030688
(CHEMBL122917 | N-(3-{3-Butyl-4-[2'-(3,3-dimethyl-b...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)CC(C)(C)C Show InChI InChI=1S/C35H39F4N5O5S/c1-6-8-13-30-41-44(28-19-24(40-31(45)7-2)16-17-26(28)35(37,38)39)33(47)43(30)21-23-15-14-22(18-27(23)36)25-11-9-10-12-29(25)50(48,49)42-32(46)20-34(3,4)5/h9-12,14-19H,6-8,13,20-21H2,1-5H3,(H,40,45)(H,42,46) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030712
(2-Ethoxy-N-{3-[4-(3-fluoro-2'-(N-t-butyloxycarbony...)Show SMILES CCCc1nn(-c2cc(NC(=O)COCC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C34H37F4N5O7S/c1-6-10-29-40-43(27-18-23(39-30(44)20-49-7-2)15-16-25(27)34(36,37)38)32(46)42(29)19-22-14-13-21(17-26(22)35)24-11-8-9-12-28(24)51(47,48)41-31(45)50-33(3,4)5/h8-9,11-18H,6-7,10,19-20H2,1-5H3,(H,39,44)(H,41,45) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.200 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030730
(CHEMBL341369 | Pentanoic acid {4-bromo-3-[4-(3-flu...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C34H39BrFN5O6S/c1-6-8-14-31(42)37-24-17-18-26(35)28(20-24)41-33(44)40(30(38-41)11-7-2)21-23-16-15-22(19-27(23)36)25-12-9-10-13-29(25)48(45,46)39-32(43)47-34(3,4)5/h9-10,12-13,15-20H,6-8,11,14,21H2,1-5H3,(H,37,42)(H,39,43) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030713
(5-n-Butyl-4-[[2'-[N-(tert-butoxycarbonyl)sulfamoyl...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H38ClN5O6S/c1-6-8-13-29-36-39(27-20-24(18-19-26(27)34)35-30(40)7-2)32(42)38(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)46(43,44)37-31(41)45-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,35,40)(H,37,41) | PDB
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UniProtKB/SwissProt
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Similars
| Article
| n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030730
(CHEMBL341369 | Pentanoic acid {4-bromo-3-[4-(3-flu...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CCC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)OC(C)(C)C)c1=O Show InChI InChI=1S/C34H39BrFN5O6S/c1-6-8-14-31(42)37-24-17-18-26(35)28(20-24)41-33(44)40(30(38-41)11-7-2)21-23-16-15-22(19-27(23)36)25-12-9-10-13-29(25)48(45,46)39-32(43)47-34(3,4)5/h9-10,12-13,15-20H,6-8,11,14,21H2,1-5H3,(H,37,42)(H,39,43) | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030713
(5-n-Butyl-4-[[2'-[N-(tert-butoxycarbonyl)sulfamoyl...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Cl)c(=O)n1Cc1ccc(cc1)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H38ClN5O6S/c1-6-8-13-29-36-39(27-20-24(18-19-26(27)34)35-30(40)7-2)32(42)38(29)21-22-14-16-23(17-15-22)25-11-9-10-12-28(25)46(43,44)37-31(41)45-33(3,4)5/h9-12,14-20H,6-8,13,21H2,1-5H3,(H,35,40)(H,37,41) | PDB
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UniProtKB/SwissProt
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| CHEMBL PC cid PC sid UniChem
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Similars
| Article
| n/a | n/a | 0.210 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030707
(CHEMBL122273 | Pentanoic acid (4-bromo-3-{3-ethyl-...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2F)c1=O Show InChI InChI=1S/C35H32BrF2N5O5S/c1-3-5-14-33(44)39-24-17-18-27(36)30(20-24)43-35(46)42(32(4-2)40-43)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030706
(CHEMBL125280 | N-(3-{3-Butyl-4-[3-fluoro-2'-(2-flu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1F Show InChI InChI=1S/C36H32F5N5O5S/c1-3-5-14-32-43-46(30-20-24(42-33(47)4-2)17-18-27(30)36(39,40)41)35(49)45(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)52(50,51)44-34(48)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,42,47)(H,44,48) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030707
(CHEMBL122273 | Pentanoic acid (4-bromo-3-{3-ethyl-...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2ccccc2F)c1=O Show InChI InChI=1S/C35H32BrF2N5O5S/c1-3-5-14-33(44)39-24-17-18-27(36)30(20-24)43-35(46)42(32(4-2)40-43)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)49(47,48)41-34(45)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,39,44)(H,41,45) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030706
(CHEMBL125280 | N-(3-{3-Butyl-4-[3-fluoro-2'-(2-flu...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)c1ccccc1F Show InChI InChI=1S/C36H32F5N5O5S/c1-3-5-14-32-43-46(30-20-24(42-33(47)4-2)17-18-27(30)36(39,40)41)35(49)45(32)21-23-16-15-22(19-29(23)38)25-10-7-9-13-31(25)52(50,51)44-34(48)26-11-6-8-12-28(26)37/h6-13,15-20H,3-5,14,21H2,1-2H3,(H,42,47)(H,44,48) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Patents
Similars
| Article
| n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030691
(CHEMBL122380 | Pentanoic acid (4-bromo-3-{4-[2'-(2...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(F)ccc2F)c1=O Show InChI InChI=1S/C35H31BrF3N5O5S/c1-3-5-10-33(45)40-24-14-15-27(36)30(19-24)44-35(47)43(32(4-2)41-44)20-22-12-11-21(17-29(22)39)25-8-6-7-9-31(25)50(48,49)42-34(46)26-18-23(37)13-16-28(26)38/h6-9,11-19H,3-5,10,20H2,1-2H3,(H,40,45)(H,42,46) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030691
(CHEMBL122380 | Pentanoic acid (4-bromo-3-{4-[2'-(2...)Show SMILES CCCCC(=O)Nc1ccc(Br)c(c1)-n1nc(CC)n(Cc2ccc(cc2F)-c2ccccc2S(=O)(=O)NC(=O)c2cc(F)ccc2F)c1=O Show InChI InChI=1S/C35H31BrF3N5O5S/c1-3-5-10-33(45)40-24-14-15-27(36)30(19-24)44-35(47)43(32(4-2)41-44)20-22-12-11-21(17-29(22)39)25-8-6-7-9-31(25)50(48,49)42-34(46)26-18-23(37)13-16-28(26)38/h6-9,11-19H,3-5,10,20H2,1-2H3,(H,40,45)(H,42,46) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.230 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030725
(CHEMBL331455 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-i-p...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)C Show InChI InChI=1S/C33H35F4N5O6S/c1-5-7-12-29-39-42(27-18-23(38-30(43)6-2)15-16-25(27)33(35,36)37)32(45)41(29)19-22-14-13-21(17-26(22)34)24-10-8-9-11-28(24)49(46,47)40-31(44)48-20(3)4/h8-11,13-18,20H,5-7,12,19H2,1-4H3,(H,38,43)(H,40,44) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030717
(CHEMBL338342 | N-{4-Bromo-3-[4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C36H35BrFN5O6S/c1-5-11-32-40-43(30-21-26(18-19-28(30)37)39-33(44)23-12-7-6-8-13-23)35(46)42(32)22-25-17-16-24(20-29(25)38)27-14-9-10-15-31(27)50(47,48)41-34(45)49-36(2,3)4/h6-10,12-21H,5,11,22H2,1-4H3,(H,39,44)(H,41,45) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030725
(CHEMBL331455 | N-{3-[3-Butyl-4-(3-fluoro-2'-(N-i-p...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2C(F)(F)F)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)C Show InChI InChI=1S/C33H35F4N5O6S/c1-5-7-12-29-39-42(27-18-23(38-30(43)6-2)15-16-25(27)33(35,36)37)32(45)41(29)19-22-14-13-21(17-26(22)34)24-10-8-9-11-28(24)49(46,47)40-31(44)48-20(3)4/h8-11,13-18,20H,5-7,12,19H2,1-4H3,(H,38,43)(H,40,44) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030717
(CHEMBL338342 | N-{4-Bromo-3-[4-(3-fluoro-2-(N-t-bu...)Show SMILES CCCc1nn(-c2cc(NC(=O)c3ccccc3)ccc2Br)c(=O)n1Cc1ccc(cc1F)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C36H35BrFN5O6S/c1-5-11-32-40-43(30-21-26(18-19-28(30)37)39-33(44)23-12-7-6-8-13-23)35(46)42(32)22-25-17-16-24(20-29(25)38)27-14-9-10-15-31(27)50(47,48)41-34(45)49-36(2,3)4/h6-10,12-21H,5,11,22H2,1-4H3,(H,39,44)(H,41,45) | PDB
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UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.240 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030733
(CHEMBL125231 | N-{4-Bromo-3-[3-butyl-4-(3-chloro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1Cl)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37BrClN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.25 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |
Type-1 angiotensin II receptor
(RABBIT) | BDBM50030733
(CHEMBL125231 | N-{4-Bromo-3-[3-butyl-4-(3-chloro-2...)Show SMILES CCCCc1nn(-c2cc(NC(=O)CC)ccc2Br)c(=O)n1Cc1ccc(cc1Cl)-c1ccccc1S(=O)(=O)NC(=O)OC(C)(C)C Show InChI InChI=1S/C33H37BrClN5O6S/c1-6-8-13-29-37-40(27-19-23(16-17-25(27)34)36-30(41)7-2)32(43)39(29)20-22-15-14-21(18-26(22)35)24-11-9-10-12-28(24)47(44,45)38-31(42)46-33(3,4)5/h9-12,14-19H,6-8,13,20H2,1-5H3,(H,36,41)(H,38,42) | PDB
KEGG
UniProtKB/SwissProt
GoogleScholar AffyNet
| CHEMBL PC cid PC sid UniChem
Similars
| Article
| n/a | n/a | 0.250 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA
| Assay Description Antagonist activity at Oryctolagus cuniculus (rabbit) aortic AT1 receptor |
Citation and Details
Article DOI: 10.1007/s00044-011-9815-x BindingDB Entry DOI: 10.7270/Q2VT1W0S |
More data for this Ligand-Target Pair | |