Compile Data Set for Download or QSAR

Found 47 hits Enz. Inhib. hit(s) with all data for entry = 50007358   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508783 (CHEMBL3325515) Show SMILES CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(OC)c1ccccc1 Show InChI InChI=1S/C19H18ClNO3/c1-3-24-19(22)17-16(14-11-13(20)9-10-15(14)21-17)18(23-2)12-7-5-4-6-8-12/h4-11,18,21H,3H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	21	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508787 (CHEMBL3325519) Show SMILES CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(OC)c1cc(C)cc(C)c1 Show InChI InChI=1S/C21H22ClNO3/c1-5-26-21(24)19-18(16-11-15(22)6-7-17(16)23-19)20(25-4)14-9-12(2)8-13(3)10-14/h6-11,20,23H,5H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	34	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508782 (CHEMBL3774725) Show SMILES CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(SC)c1ccccc1 Show InChI InChI=1S/C19H18ClNO2S/c1-3-23-19(22)17-16(14-11-13(20)9-10-15(14)21-17)18(24-2)12-7-5-4-6-8-12/h4-11,18,21H,3H2,1-2H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	39	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508784 (CHEMBL4543868) Show SMILES CCCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C17H14ClN3O2/c1-2-6-21-16-14(20-17(21)22)4-3-5-15(16)23-13-8-11(10-19)7-12(18)9-13/h3-5,7-9H,2,6H2,1H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	52	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508789 (CHEMBL3775346) Show SMILES CCOC(=O)c1[nH]c2ccc(Cl)cc2c1C(SC)c1cc(C)cc(C)c1 Show InChI InChI=1S/C21H22ClNO2S/c1-5-25-21(24)19-18(16-11-15(22)6-7-17(16)23-19)20(26-4)14-9-12(2)8-13(3)10-14/h6-11,20,23H,5H2,1-4H3	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508792 (CHEMBL4579182) Show SMILES CCn1c2c(Oc3cc(cc(c3)C#N)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C17H12N4O2/c1-2-21-16-14(20-17(21)22)4-3-5-15(16)23-13-7-11(9-18)6-12(8-13)10-19/h3-8H,2H2,1H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	74	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM1434 (11-cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3...) Show SMILES Cc1ccnc2N(C3CC3)c3ncccc3C(=O)Nc12 Show InChI InChI=1S/C15H14N4O/c1-9-6-8-17-14-12(9)18-15(20)11-3-2-7-16-13(11)19(14)10-4-5-10/h2-3,6-8,10H,4-5H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	105	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	107	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	126	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	166	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508781 (CHEMBL4577391) Show SMILES CCC(c1ccccc1)n1c2cc(Cl)ccc2[nH]c1=O Show InChI InChI=1S/C16H15ClN2O/c1-2-14(11-6-4-3-5-7-11)19-15-10-12(17)8-9-13(15)18-16(19)20/h3-10,14H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>200	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y181C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	236	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188C mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	293	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508791 (CHEMBL4439382) Show SMILES CCn1c2c(Oc3cc(C)cc(C)c3)cccc2[nH]c1=O Show InChI InChI=1S/C17H18N2O2/c1-4-19-16-14(18-17(19)20)6-5-7-15(16)21-13-9-11(2)8-12(3)10-13/h5-10H,4H2,1-3H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	303	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	377	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508779 (CHEMBL4450185) Show SMILES CCn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C16H12ClN3O2/c1-2-20-15-13(19-16(20)21)4-3-5-14(15)22-12-7-10(9-18)6-11(17)8-12/h3-8H,2H2,1H3,(H,19,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	415	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	468	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508776 (CHEMBL4470380) Show SMILES Cn1c2c(Oc3cc(Cl)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H10ClN3O2/c1-19-14-12(18-15(19)20)3-2-4-13(14)21-11-6-9(8-17)5-10(16)7-11/h2-7H,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	494	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	630	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	798	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	894	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase K103N/Y181C double mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508777 (CHEMBL4438953) Show SMILES CCn1c2c(Oc3cc(\C=C\C#N)cc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C19H14N4O2/c1-2-23-18-16(22-19(23)24)6-3-7-17(18)25-15-10-13(5-4-8-20)9-14(11-15)12-21/h3-7,9-11H,2H2,1H3,(H,22,24)/b5-4+	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	926	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase V106M mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase Y188H mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508786 (CHEMBL4441079) Show SMILES CCn1c2c(Oc3cc(ccn3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H12N4O2/c1-2-19-14-11(18-15(19)20)4-3-5-12(14)21-13-8-10(9-16)6-7-17-13/h3-8H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.36E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508788 (CHEMBL4519998) Show SMILES CCn1c2c(Oc3cccc4ccccc34)cccc2[nH]c1=O Show InChI InChI=1S/C19H16N2O2/c1-2-21-18-15(20-19(21)22)10-6-12-17(18)23-16-11-5-8-13-7-3-4-9-14(13)16/h3-12H,2H2,1H3,(H,20,22)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.27E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508778 (CHEMBL4450262) Show SMILES CC1(C)OC(=O)Nc2cccc(Oc3cc(Cl)cc(c3)C#N)c12 Show InChI InChI=1S/C17H13ClN2O3/c1-17(2)15-13(20-16(21)23-17)4-3-5-14(15)22-12-7-10(9-19)6-11(18)8-12/h3-8H,1-2H3,(H,20,21)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.76E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of HIV1 reverse transcriptase G190A mutant in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infecti...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508780 (CHEMBL4520231) Show SMILES CCn1c2c(Oc3ccccc3)cccc2[nH]c1=O Show InChI InChI=1S/C15H14N2O2/c1-2-17-14-12(16-15(17)18)9-6-10-13(14)19-11-7-4-3-5-8-11/h3-10H,2H2,1H3,(H,16,18)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.88E+3	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508790 (CHEMBL4584925) Show SMILES CCn1c2c(Oc3ccnc(c3)C#N)cccc2[nH]c1=O Show InChI InChI=1S/C15H12N4O2/c1-2-19-14-12(18-15(19)20)4-3-5-13(14)21-11-6-7-17-10(8-11)9-16/h3-8H,2H2,1H3,(H,18,20)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.33E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair
Reverse transcriptase (Human immunodeficiency virus 1)	BDBM50508785 (CHEMBL4459834) Show SMILES CCn1c2c(Oc3ccnc(Cl)c3)cccc2[nH]c1=O Show InChI InChI=1S/C14H12ClN3O2/c1-2-18-13-10(17-14(18)19)4-3-5-11(13)20-9-6-7-16-12(15)8-9/h3-8H,2H2,1H3,(H,17,19)	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>4.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Stellenbosch University Curated by ChEMBL					Assay Description Inhibition of wild-type HIV1 reverse transcriptase in HIV1 infected HEK293T cells harboring luciferase gene assessed as reduction in viral infection ...				ACS Med Chem Lett 10: 196-202 (2019) Article DOI: 10.1021/acsmedchemlett.8b00549 BindingDB Entry DOI: 10.7270/Q2CJ8HS3
					More data for this Ligand-Target Pair