Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for entry = 50010342   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537772 (CHEMBL4633023) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(F)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28FN3OS/c1-2-27-13-5-14-30-15-12-22-21-6-3-4-7-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.68E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537785 (CHEMBL4645801) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(F)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28FN3OS/c1-2-27-12-6-13-30-14-11-22-21-9-3-4-10-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-8-5-7-18(28)15-19/h3-5,7-10,15-16,25H,2,6,11-14,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537786 (CHEMBL4639838) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccccc1F)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28FN3OS/c1-2-27-13-7-14-30-15-12-20-19-8-3-6-11-23(19)31(24(20)25(27)30)18(16-27)17-32-26(33)29-22-10-5-4-9-21(22)28/h3-6,8-11,16,25H,2,7,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.24E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537770 (CHEMBL4642086) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)NC1CCCCC1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H35N3OS/c1-2-27-14-8-15-29-16-13-22-21-11-6-7-12-23(21)30(24(22)25(27)29)20(17-27)18-31-26(32)28-19-9-4-3-5-10-19/h6-7,11-12,17,19,25H,2-5,8-10,13-16,18H2,1H3,(H,28,32)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.06E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537798 (CHEMBL4637690) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)N(C(=O)N1CCOCC1)c1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C32H36N4O3S/c1-2-32-14-8-15-33-16-13-26-25-11-6-7-12-27(25)35(28(26)29(32)33)24(21-32)22-39-31(40)36(23-9-4-3-5-10-23)30(37)34-17-19-38-20-18-34/h3-7,9-12,21,29H,2,8,13-20,22H2,1H3/t29-,32+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8.42E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537791 (CHEMBL4640039) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(cc1)C(C)(C)C)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C31H37N3OS/c1-5-31-16-8-17-33-18-15-25-24-9-6-7-10-26(24)34(27(25)28(31)33)23(19-31)20-35-29(36)32-22-13-11-21(12-14-22)30(2,3)4/h6-7,9-14,19,28H,5,8,15-18,20H2,1-4H3,(H,32,36)/t28-,31+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.21E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537792 (CHEMBL4638576) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO\C(SC)=N\c1ccc(C)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C29H33N3OS/c1-4-29-15-7-16-31-17-14-24-23-8-5-6-9-25(23)32(26(24)27(29)31)22(18-29)19-33-28(34-3)30-21-12-10-20(2)11-13-21/h5-6,8-13,18,27H,4,7,14-17,19H2,1-3H3/b30-28-/t27-,29+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537773 (CHEMBL4641656) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(F)cc1F)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H27F2N3OS/c1-2-27-11-5-12-31-13-10-20-19-6-3-4-7-23(19)32(24(20)25(27)31)18(15-27)16-33-26(34)30-22-9-8-17(28)14-21(22)29/h3-4,6-9,14-15,25H,2,5,10-13,16H2,1H3,(H,30,34)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537771 (CHEMBL4632510) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)NC(C)C)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C24H31N3OS/c1-4-24-11-7-12-26-13-10-19-18-8-5-6-9-20(18)27(21(19)22(24)26)17(14-24)15-28-23(29)25-16(2)3/h5-6,8-9,14,16,22H,4,7,10-13,15H2,1-3H3,(H,25,29)/t22-,24+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537806 (CHEMBL4643091) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)Nc1ccc(Cl)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H29ClN4S/c1-2-27-13-5-14-31-15-12-22-21-6-3-4-7-23(21)32(24(22)25(27)31)20(16-27)17-29-26(33)30-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H2,29,30,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.64E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537803 (CHEMBL4633227) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)NC(=O)c1ccc(OC)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C29H32N4O2S/c1-3-29-14-6-15-32-16-13-23-22-7-4-5-8-24(22)33(25(23)26(29)32)20(17-29)18-30-28(36)31-27(34)19-9-11-21(35-2)12-10-19/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3,(H2,30,31,34,36)/t26-,29+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537775 (CHEMBL4633680) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(OC)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3O2S/c1-3-28-13-7-14-30-15-12-23-22-10-4-5-11-24(22)31(25(23)26(28)30)20(17-28)18-33-27(34)29-19-8-6-9-21(16-19)32-2/h4-6,8-11,16-17,26H,3,7,12-15,18H2,1-2H3,(H,29,34)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.86E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50059033 ((11aS,11bS)-11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H...) Show SMILES CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@H]23)n1c1ccccc41 |t:5| Show InChI InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	1.88E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537787 (CHEMBL4635828) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(SC)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3OS2/c1-3-28-14-6-15-30-16-13-23-22-7-4-5-8-24(22)31(25(23)26(28)30)20(17-28)18-32-27(33)29-19-9-11-21(34-2)12-10-19/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3,(H,29,33)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537774 (CHEMBL4640085) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(OC)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3O2S/c1-3-28-14-6-15-30-16-13-23-22-7-4-5-8-24(22)31(25(23)26(28)30)20(17-28)18-33-27(34)29-19-9-11-21(32-2)12-10-19/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3,(H,29,34)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.95E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537766 (CHEMBL4646903) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C20H24N2O/c1-2-20-9-5-10-21-11-8-16-15-6-3-4-7-17(15)22(14(12-20)13-23)18(16)19(20)21/h3-4,6-7,12,19,23H,2,5,8-11,13H2,1H3/t19-,20+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.43E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537767 (CHEMBL4639072) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H29N3OS/c1-2-27-14-8-15-29-16-13-22-21-11-6-7-12-23(21)30(24(22)25(27)29)20(17-27)18-31-26(32)28-19-9-4-3-5-10-19/h3-7,9-12,17,25H,2,8,13-16,18H2,1H3,(H,28,32)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.48E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537795 (CHEMBL4638744) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO\C(SC)=N\c1ccccc1F)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H30FN3OS/c1-3-28-14-8-15-31-16-13-21-20-9-4-7-12-24(20)32(25(21)26(28)31)19(17-28)18-33-27(34-2)30-23-11-6-5-10-22(23)29/h4-7,9-12,17,26H,3,8,13-16,18H2,1-2H3/b30-27-/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.62E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537802 (CHEMBL4636663) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)NC(=O)c1ccc(F)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H29FN4OS/c1-2-28-13-5-14-32-15-12-22-21-6-3-4-7-23(21)33(24(22)25(28)32)20(16-28)17-30-27(35)31-26(34)18-8-10-19(29)11-9-18/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H2,30,31,34,35)/t25-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537793 (CHEMBL4633277) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO\C(SC)=N\c1ccc(F)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H30FN3OS/c1-3-28-14-6-15-31-16-13-23-22-7-4-5-8-24(22)32(25(23)26(28)31)21(17-28)18-33-27(34-2)30-20-11-9-19(29)10-12-20/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3/b30-27-/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.01E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537794 (CHEMBL4644211) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO\C(SC)=N\c1cccc(F)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H30FN3OS/c1-3-28-13-7-14-31-15-12-23-22-10-4-5-11-24(22)32(25(23)26(28)31)21(17-28)18-33-27(34-2)30-20-9-6-8-19(29)16-20/h4-6,8-11,16-17,26H,3,7,12-15,18H2,1-2H3/b30-27-/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.07E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537768 (CHEMBL4649020) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)NC)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C22H27N3OS/c1-3-22-10-6-11-24-12-9-17-16-7-4-5-8-18(16)25(19(17)20(22)24)15(13-22)14-26-21(27)23-2/h4-5,7-8,13,20H,3,6,9-12,14H2,1-2H3,(H,23,27)/t20-,22+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.09E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537800 (CHEMBL4642588) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CN)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C20H25N3/c1-2-20-9-5-10-22-11-8-16-15-6-3-4-7-17(15)23(14(12-20)13-21)18(16)19(20)22/h3-4,6-7,12,19H,2,5,8-11,13,21H2,1H3/t19-,20+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.32E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537779 (CHEMBL4643016) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)NCc1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3OS/c1-2-28-14-8-15-30-16-13-23-22-11-6-7-12-24(22)31(25(23)26(28)30)21(17-28)19-32-27(33)29-18-20-9-4-3-5-10-20/h3-7,9-12,17,26H,2,8,13-16,18-19H2,1H3,(H,29,33)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.83E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537782 (CHEMBL4643199) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(C)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3OS/c1-3-28-13-7-14-30-15-12-23-22-10-4-5-11-24(22)31(25(23)26(28)30)21(17-28)18-32-27(33)29-20-9-6-8-19(2)16-20/h4-6,8-11,16-17,26H,3,7,12-15,18H2,1-2H3,(H,29,33)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.99E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537783 (CHEMBL4638154) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccccc1C)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3OS/c1-3-28-14-8-15-30-16-13-22-21-10-5-7-12-24(21)31(25(22)26(28)30)20(17-28)18-32-27(33)29-23-11-6-4-9-19(23)2/h4-7,9-12,17,26H,3,8,13-16,18H2,1-2H3,(H,29,33)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.11E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537807 (CHEMBL4649694) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(C)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H31N3OS/c1-3-28-14-6-15-30-16-13-23-22-7-4-5-8-24(22)31(25(23)26(28)30)21(17-28)18-32-27(33)29-20-11-9-19(2)10-12-20/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3,(H,29,33)/t26-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.23E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537796 (CHEMBL4633805) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)N(C(=O)c1ccccc1)c1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C34H33N3O2S/c1-2-34-19-11-20-35-21-18-28-27-16-9-10-17-29(27)36(30(28)31(34)35)26(22-34)23-39-33(40)37(25-14-7-4-8-15-25)32(38)24-12-5-3-6-13-24/h3-10,12-17,22,31H,2,11,18-21,23H2,1H3/t31-,34+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.76E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537804 (CHEMBL4648572) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)NC(=O)OCC)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C24H30N4O2S/c1-3-24-11-7-12-27-13-10-18-17-8-5-6-9-19(17)28(20(18)21(24)27)16(14-24)15-25-22(31)26-23(29)30-4-2/h5-6,8-9,14,21H,3-4,7,10-13,15H2,1-2H3,(H2,25,26,29,31)/t21-,24+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537789 (CHEMBL4644378) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(Br)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28BrN3OS/c1-2-27-13-5-14-30-15-12-22-21-6-3-4-7-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.93E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537799 (CHEMBL4633185) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CN1C(=O)c4ccccc4C1=O)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H27N3O2/c1-2-28-13-7-14-29-15-12-20-19-8-5-6-11-23(19)31(24(20)25(28)29)18(16-28)17-30-26(32)21-9-3-4-10-22(21)27(30)33/h3-6,8-11,16,25H,2,7,12-15,17H2,1H3/t25-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537777 (CHEMBL4640548) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccccc1Br)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28BrN3OS/c1-2-27-13-7-14-30-15-12-20-19-8-3-6-11-23(19)31(24(20)25(27)30)18(16-27)17-32-26(33)29-22-10-5-4-9-21(22)28/h3-6,8-11,16,25H,2,7,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537790 (CHEMBL4639361) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(Cl)c1Cl)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H27Cl2N3OS/c1-2-27-12-6-13-31-14-11-19-18-7-3-4-10-22(18)32(24(19)25(27)31)17(15-27)16-33-26(34)30-21-9-5-8-20(28)23(21)29/h3-5,7-10,15,25H,2,6,11-14,16H2,1H3,(H,30,34)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537778 (CHEMBL4643153) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc4ccccc14)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C31H31N3OS/c1-2-31-16-8-17-33-18-15-25-24-12-5-6-14-27(24)34(28(25)29(31)33)22(19-31)20-35-30(36)32-26-13-7-10-21-9-3-4-11-23(21)26/h3-7,9-14,19,29H,2,8,15-18,20H2,1H3,(H,32,36)/t29-,31+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5.84E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537797 (CHEMBL4643200) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)N(C(=O)C1CC1)c1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C31H33N3O2S/c1-2-31-16-8-17-32-18-15-25-24-11-6-7-12-26(24)33(27(25)28(31)32)23(19-31)20-36-30(37)34(29(35)21-13-14-21)22-9-4-3-5-10-22/h3-7,9-12,19,21,28H,2,8,13-18,20H2,1H3/t28-,31+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.02E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537784 (CHEMBL4648949) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(c1)C(F)(F)F)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H28F3N3OS/c1-2-27-12-6-13-33-14-11-22-21-9-3-4-10-23(21)34(24(22)25(27)33)20(16-27)17-35-26(36)32-19-8-5-7-18(15-19)28(29,30)31/h3-5,7-10,15-16,25H,2,6,11-14,17H2,1H3,(H,32,36)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.25E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537769 (CHEMBL4635813) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(cc1)C(F)(F)F)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H28F3N3OS/c1-2-27-13-5-14-33-15-12-22-21-6-3-4-7-23(21)34(24(22)25(27)33)20(16-27)17-35-26(36)32-19-10-8-18(9-11-19)28(29,30)31/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H,32,36)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537801 (CHEMBL4643607) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)NC(=O)c1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C28H30N4OS/c1-2-28-14-8-15-31-16-13-22-21-11-6-7-12-23(21)32(24(22)25(28)31)20(17-28)18-29-27(34)30-26(33)19-9-4-3-5-10-19/h3-7,9-12,17,25H,2,8,13-16,18H2,1H3,(H2,29,30,33,34)/t25-,28+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.42E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537805 (CHEMBL4646556) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)Nc1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H30N4S/c1-2-27-14-8-15-30-16-13-22-21-11-6-7-12-23(21)31(24(22)25(27)30)20(17-27)18-28-26(32)29-19-9-4-3-5-10-19/h3-7,9-12,17,25H,2,8,13-16,18H2,1H3,(H2,28,29,32)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.47E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537780 (CHEMBL4639100) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccccc1Cl)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28ClN3OS/c1-2-27-13-7-14-30-15-12-20-19-8-3-6-11-23(19)31(24(20)25(27)30)18(16-27)17-32-26(33)29-22-10-5-4-9-21(22)28/h3-6,8-11,16,25H,2,7,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.58E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537776 (CHEMBL4649811) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(Cl)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28ClN3OS/c1-2-27-13-5-14-30-15-12-22-21-6-3-4-7-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6.74E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537781 (CHEMBL4636207) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(Cl)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28ClN3OS/c1-2-27-12-6-13-30-14-11-22-21-9-3-4-10-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-8-5-7-18(28)15-19/h3-5,7-10,15-16,25H,2,6,11-14,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.20E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537788 (CHEMBL4644704) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(OC)cc1OC)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C29H33N3O3S/c1-4-29-13-7-14-31-15-12-22-21-8-5-6-9-24(21)32(26(22)27(29)31)19(17-29)18-35-28(36)30-23-11-10-20(33-2)16-25(23)34-3/h5-6,8-11,16-17,27H,4,7,12-15,18H2,1-3H3,(H,30,36)/t27-,29+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.44E+4	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PDE1A (unknown origin)				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537806 (CHEMBL4643091) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)Nc1ccc(Cl)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H29ClN4S/c1-2-27-13-5-14-31-15-12-22-21-6-3-4-7-23(21)32(24(22)25(27)31)20(16-27)17-29-26(33)30-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H2,29,30,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537803 (CHEMBL4633227) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CNC(=S)NC(=O)c1ccc(OC)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C29H32N4O2S/c1-3-29-14-6-15-32-16-13-23-22-7-4-5-8-24(22)33(25(23)26(29)32)20(17-29)18-30-28(36)31-27(34)19-9-11-21(35-2)12-10-19/h4-5,7-12,17,26H,3,6,13-16,18H2,1-2H3,(H2,30,31,34,36)/t26-,29+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	68	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537798 (CHEMBL4637690) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)N(C(=O)N1CCOCC1)c1ccccc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C32H36N4O3S/c1-2-32-14-8-15-33-16-13-26-25-11-6-7-12-27(25)35(28(26)29(32)33)24(21-32)22-39-31(40)36(23-9-4-3-5-10-23)30(37)34-17-19-38-20-18-34/h3-7,9-12,21,29H,2,8,13-20,22H2,1H3/t29-,32+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	6.80	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537792 (CHEMBL4638576) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(CO\C(SC)=N\c1ccc(C)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C29H33N3OS/c1-4-29-15-7-16-31-17-14-24-23-8-5-6-9-25(23)32(26(24)27(29)31)22(18-29)19-33-28(34-3)30-21-12-10-20(2)11-13-21/h5-6,8-13,18,27H,4,7,14-17,19H2,1-3H3/b30-28-/t27-,29+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537785 (CHEMBL4645801) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1cccc(F)c1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28FN3OS/c1-2-27-12-6-13-30-14-11-22-21-9-3-4-10-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-8-5-7-18(28)15-19/h3-5,7-10,15-16,25H,2,6,11-14,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50537772 (CHEMBL4633023) Show SMILES [H][C@]12N3CCC[C@@]1(CC)C=C(COC(=S)Nc1ccc(F)cc1)n1c2c(CC3)c2ccccc12 |r,t:10| Show InChI InChI=1S/C27H28FN3OS/c1-2-27-13-5-14-30-15-12-22-21-6-3-4-7-23(21)31(24(22)25(27)30)20(16-27)17-32-26(33)29-19-10-8-18(28)9-11-19/h3-4,6-11,16,25H,2,5,12-15,17H2,1H3,(H,29,33)/t25-,27+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair
Dual specificity calcium/calmodulin-dependent 3',5'-cyclic nucleotide phosphodiesterase 1A (Homo sapiens (Human))	BDBM50059033 ((11aS,11bS)-11a-Ethyl-2,3,4,5,11a,11b-hexahydro-1H...) Show SMILES CCOC(=O)C1=C[C@]2(CC)CCCN3CCc4c([C@H]23)n1c1ccccc41 |t:5| Show InChI InChI=1S/C22H26N2O2/c1-3-22-11-7-12-23-13-10-16-15-8-5-6-9-17(15)24(19(16)20(22)23)18(14-22)21(25)26-4-2/h5-6,8-9,14,20H,3-4,7,10-13H2,1-2H3/t20-,22+/m1/s1	KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Binding affinity to PDE1A (unknown origin) assessed as dissociation constant by SPR assay				Bioorg Med Chem Lett 30: (2020) Article DOI: 10.1016/j.bmcl.2019.05.052 BindingDB Entry DOI: 10.7270/Q2VX0M21
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 51 total )  |  Next  |  Last  >>

Jump to: