Compile Data Set for Download or QSAR

Found 62 hits Enz. Inhib. hit(s) with all data for entry = 50014729   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579557 (CHEMBL4868362) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C1(CC1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579561 (CHEMBL4871543) Show SMILES COc1nn(CC2CC2)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579568 (CHEMBL4875364) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3cccnc23)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579560 (CHEMBL4857751) Show SMILES CCn1cc(C(=O)Nc2cccc(n2)-c2nncn2[C@@H](C)C(F)(F)F)c(OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579563 (CHEMBL4850048) Show SMILES COCCn1cc(C(=O)Nc2cccc(n2)-c2nncn2[C@@H](C)C(F)(F)F)c(OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579564 (CHEMBL4866921) Show SMILES COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F)-c1cnccn1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579566 (CHEMBL4861953) Show SMILES COc1ccccc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579572 (CHEMBL4853505) Show SMILES COc1ncc(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579569 (CHEMBL4877113) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3nccnc23)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579565 (CHEMBL4862847) Show SMILES COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F)-c1cccnn1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579562 (CHEMBL4862258) Show SMILES COc1nn(CC(F)(F)F)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579553 (CHEMBL4860819) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579559 (CHEMBL4876558) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C1CCC1(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579551 (CHEMBL4860731) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H]1CCOC1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579556 (CHEMBL4878163) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50538424 (CHEMBL4643577) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C Show InChI InChI=1S/C16H19N7O2/c1-10(2)23-9-17-20-14(23)12-6-5-7-13(18-12)19-15(24)11-8-22(3)21-16(11)25-4/h5-10H,1-4H3,(H,18,19,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579547 (CHEMBL4865259) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)CO Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579559 (CHEMBL4876558) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C1CCC1(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579556 (CHEMBL4878163) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579545 (CHEMBL4852061) Show SMILES COc1ncccc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579546 (CHEMBL4849014) Show SMILES COc1ncc(F)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579567 (CHEMBL4874460) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3N(C)CCOc23)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579550 (CHEMBL4848618) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@H]1CCOC1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579561 (CHEMBL4871543) Show SMILES COc1nn(CC2CC2)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579552 (CHEMBL4857053) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579560 (CHEMBL4857751) Show SMILES CCn1cc(C(=O)Nc2cccc(n2)-c2nncn2[C@@H](C)C(F)(F)F)c(OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579563 (CHEMBL4850048) Show SMILES COCCn1cc(C(=O)Nc2cccc(n2)-c2nncn2[C@@H](C)C(F)(F)F)c(OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579553 (CHEMBL4860819) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579571 (CHEMBL4862220) Show SMILES COc1ncncc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579570 (CHEMBL4873779) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccn(C)c2=O)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579558 (CHEMBL4860716) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C1CC(F)(F)C1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	20	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579546 (CHEMBL4849014) Show SMILES COc1ncc(F)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579545 (CHEMBL4852061) Show SMILES COc1ncccc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579548 (CHEMBL4867144) Show SMILES COC[C@@H](C)n1cnnc1-c1cccc(NC(=O)c2cn(C)nc2OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579557 (CHEMBL4868362) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C1(CC1)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579562 (CHEMBL4862258) Show SMILES COc1nn(CC(F)(F)F)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579555 (CHEMBL4864439) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@H](C)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579552 (CHEMBL4857053) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C(F)(F)F Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579549 (CHEMBL4867281) Show SMILES COC[C@H](C)n1cnnc1-c1cccc(NC(=O)c2cn(C)nc2OC)n1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	44	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579565 (CHEMBL4862847) Show SMILES COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F)-c1cccnn1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579569 (CHEMBL4877113) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3nccnc23)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579572 (CHEMBL4853505) Show SMILES COc1ncc(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579566 (CHEMBL4861953) Show SMILES COc1ccccc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	53	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579564 (CHEMBL4866921) Show SMILES COc1nn(cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H](C)C(F)(F)F)-c1cnccn1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	58	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579568 (CHEMBL4875364) Show SMILES C[C@H](n1cnnc1-c1cccc(NC(=O)c2cccc3cccnc23)n1)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50538424 (CHEMBL4643577) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1C(C)C Show InChI InChI=1S/C16H19N7O2/c1-10(2)23-9-17-20-14(23)12-6-5-7-13(18-12)19-15(24)11-8-22(3)21-16(11)25-4/h5-10H,1-4H3,(H,18,19,24)	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579554 (CHEMBL4863056) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@H](C)C(F)(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of ASK1 (unknown origin) using myelin basic protein as substrate preincubated for 20 mins followed by 33P-ATP addition and measured after ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579551 (CHEMBL4860731) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@@H]1CCOC1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	129	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579555 (CHEMBL4864439) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@H](C)C(F)F |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	143	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair
Mitogen-activated protein kinase kinase kinase 5 (Homo sapiens (Human))	BDBM50579550 (CHEMBL4848618) Show SMILES COc1nn(C)cc1C(=O)Nc1cccc(n1)-c1nncn1[C@H]1CCOC1 |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	144	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of full-length human ASK1 expressed in HEK293T cells assessed as reduction in autophosphorylation of ASK1 at T383 residue incubated for 1 ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01458 BindingDB Entry DOI: 10.7270/Q27D2ZZT
					More data for this Ligand-Target Pair

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