Compile Data Set for Download or QSAR

Found 451 hits Enz. Inhib. hit(s) with all data for entry = 629   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Plasma kallikrein (Homo sapiens (Human))	BDBM283351 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((2- cyanoqu...) Show SMILES Nc1nccc2cc(CNC(=O)c3ccnc(Cc4ccc5nc(ccc5c4)C#N)c3)ccc12 Show InChI InChI=1S/C27H20N6O/c28-15-22-4-3-20-11-17(2-6-25(20)33-22)13-23-14-21(8-9-30-23)27(34)32-16-18-1-5-24-19(12-18)7-10-31-26(24)29/h1-12,14H,13,16H2,(H2,29,31)(H,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283353 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccnc(Cc2ccc3ncc(cc3c2)C#N)c1 Show InChI InChI=1S/C26H17ClFN5O/c27-22-14-32-25-10-23(28)19(9-21(22)25)13-33-26(34)17-3-4-30-20(8-17)7-15-1-2-24-18(5-15)6-16(11-29)12-31-24/h1-6,8-10,12,14,32H,7,13H2,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283354 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- cyanoqu...) Show SMILES Nc1nccc2cc(CNC(=O)c3ccnc(Cc4ccc5ncc(cc5c4)C#N)c3)ccc12 Show InChI InChI=1S/C27H20N6O/c28-14-19-11-22-9-17(2-4-25(22)32-16-19)12-23-13-21(6-7-30-23)27(34)33-15-18-1-3-24-20(10-18)5-8-31-26(24)29/h1-11,13,16H,12,15H2,(H2,29,31)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283355 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2ccc3ncc(cc3c2)C#N)c1 Show InChI InChI=1S/C25H22N6O/c1-15-7-24(27)31-16(2)22(15)14-30-25(32)19-5-6-28-21(11-19)10-17-3-4-23-20(8-17)9-18(12-26)13-29-23/h3-9,11,13H,10,14H2,1-2H3,(H2,27,31)(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283360 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((6...) Show SMILES CS(=O)(=O)c1ccc2ncc(Cc3cc(ccn3)C(=O)NCc3cc4c(Cl)c[nH]c4cc3F)cc2c1 Show InChI InChI=1S/C26H20ClFN4O3S/c1-36(34,35)20-2-3-24-17(9-20)6-15(12-30-24)7-19-8-16(4-5-29-19)26(33)32-13-18-10-21-22(27)14-31-25(21)11-23(18)28/h2-6,8-12,14,31H,7,13H2,1H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283363 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3c(C)cc(N)nc3C)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C26H27N5O3S/c1-15-7-20-9-18(11-23(35(4,33)34)25(20)29-13-15)10-21-12-19(5-6-28-21)26(32)30-14-22-16(2)8-24(27)31-17(22)3/h5-9,11-13H,10,14H2,1-4H3,(H2,27,31)(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283364 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- methyl-...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3ccc4c(N)nccc4c3)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C28H25N5O3S/c1-17-9-22-11-19(13-25(37(2,35)36)26(22)32-15-17)12-23-14-21(6-7-30-23)28(34)33-16-18-3-4-24-20(10-18)5-8-31-27(24)29/h3-11,13-15H,12,16H2,1-2H3,(H2,29,31)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283365 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cc4c(Cl)c[nH]c4cc3F)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C27H22ClFN4O3S/c1-15-5-18-6-16(8-25(37(2,35)36)26(18)32-12-15)7-20-9-17(3-4-30-20)27(34)33-13-19-10-21-22(28)14-31-24(21)11-23(19)29/h3-6,8-12,14,31H,7,13H2,1-2H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283366 (N-((6-fluoro-1H-indol-5-yl)methyl)-2-((3- methyl-8...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cc4cc[nH]c4cc3F)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C27H23FN4O3S/c1-16-7-20-8-17(10-25(36(2,34)35)26(20)31-14-16)9-22-12-19(4-5-29-22)27(33)32-15-21-11-18-3-6-30-24(18)13-23(21)28/h3-8,10-14,30H,9,15H2,1-2H3,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283367 (N-((3-chloro-1H-pyrrolo[2,3-b]pyridin-5- yl)methyl...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cnc4[nH]cc(Cl)c4c3)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C26H22ClN5O3S/c1-15-5-19-6-16(9-23(36(2,34)35)24(19)29-11-15)7-20-10-18(3-4-28-20)26(33)32-13-17-8-21-22(27)14-31-25(21)30-12-17/h3-6,8-12,14H,7,13H2,1-2H3,(H,30,31)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283368 (N-((5-chloro-1H-indazol-3-yl)methyl)-2-((3- methyl...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3n[nH]c4ccc(Cl)cc34)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C26H22ClN5O3S/c1-15-7-18-8-16(10-24(36(2,34)35)25(18)29-13-15)9-20-11-17(5-6-28-20)26(33)30-14-23-21-12-19(27)3-4-22(21)31-32-23/h3-8,10-13H,9,14H2,1-2H3,(H,30,33)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283369 (N-((3-chloro-4-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3ccc4[nH]cc(Cl)c4c3F)cc2c1)S(C)(=O)=O Show InChI InChI=1S/C27H22ClFN4O3S/c1-15-7-19-8-16(10-23(37(2,35)36)26(19)32-12-15)9-20-11-17(5-6-30-20)27(34)33-13-18-3-4-22-24(25(18)29)21(28)14-31-22/h3-8,10-12,14,31H,9,13H2,1-2H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283377 (N-((6-amino-4-methylpyridin-3-yl)methyl)-2- ((3-ch...) Show SMILES Cc1cc(N)ncc1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C23H20ClN5O/c1-14-6-22(25)28-11-18(14)12-29-23(30)16-4-5-26-20(10-16)8-15-2-3-21-17(7-15)9-19(24)13-27-21/h2-7,9-11,13H,8,12H2,1H3,(H2,25,28)(H,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283379 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- chloroq...) Show SMILES Nc1nccc2cc(CNC(=O)c3ccnc(Cc4ccc5ncc(Cl)cc5c4)c3)ccc12 Show InChI InChI=1S/C26H20ClN5O/c27-21-12-20-9-16(2-4-24(20)31-15-21)11-22-13-19(6-7-29-22)26(33)32-14-17-1-3-23-18(10-17)5-8-30-25(23)28/h1-10,12-13,15H,11,14H2,(H2,28,30)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283381 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C25H17Cl2FN4O/c26-18-7-16-5-14(1-2-23(16)30-12-18)6-19-8-15(3-4-29-19)25(33)32-11-17-9-20-21(27)13-31-24(20)10-22(17)28/h1-5,7-10,12-13,31H,6,11H2,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283382 (N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((3-ch...) Show SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C23H20ClN5O/c1-14-17(3-5-22(25)29-14)12-28-23(30)16-6-7-26-20(11-16)9-15-2-4-21-18(8-15)10-19(24)13-27-21/h2-8,10-11,13H,9,12H2,1H3,(H2,25,29)(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283383 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C24H22ClN5O/c1-14-7-23(26)30-15(2)21(14)13-29-24(31)17-5-6-27-20(11-17)9-16-3-4-22-18(8-16)10-19(25)12-28-22/h3-8,10-12H,9,13H2,1-2H3,(H2,26,30)(H,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283385 (N-((5-chloro-1H-indazol-3-yl)methyl)-2-((3- chloro...) Show SMILES Clc1ccc2[nH]nc(CNC(=O)c3ccnc(Cc4ccc5ncc(Cl)cc5c4)c3)c2c1 Show InChI InChI=1S/C24H17Cl2N5O/c25-17-2-4-22-20(11-17)23(31-30-22)13-29-24(32)15-5-6-27-19(10-15)8-14-1-3-21-16(7-14)9-18(26)12-28-21/h1-7,9-12H,8,13H2,(H,29,32)(H,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283386 (N-((3-chloro-1H-pyrrolo[2,3-b]pyridin-5- yl)methyl...) Show SMILES Clc1c[nH]c2ncc(CNC(=O)c3ccnc(Cc4ccc5ncc(Cl)cc5c4)c3)cc12 Show InChI InChI=1S/C24H17Cl2N5O/c25-18-8-17-5-14(1-2-22(17)28-12-18)6-19-9-16(3-4-27-19)24(32)31-11-15-7-20-21(26)13-30-23(20)29-10-15/h1-5,7-10,12-13H,6,11H2,(H,29,30)(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283387 (N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((3-ch...) Show SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(CC2=CC3C=C(Cl)C=NC3C=C2)c1 |c:25,29,t:19,22| Show InChI InChI=1S/C23H22ClN5O/c1-14-17(3-5-22(25)29-14)12-28-23(30)16-6-7-26-20(11-16)9-15-2-4-21-18(8-15)10-19(24)13-27-21/h2-8,10-11,13,18,21H,9,12H2,1H3,(H2,25,29)(H,28,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283388 (N-((3-chloro-4-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Fc1c(CNC(=O)c2ccnc(Cc3ccc4ncc(Cl)cc4c3)c2)ccc2[nH]cc(Cl)c12 Show InChI InChI=1S/C25H17Cl2FN4O/c26-18-9-17-7-14(1-3-21(17)30-12-18)8-19-10-15(5-6-29-19)25(33)32-11-16-2-4-22-23(24(16)28)20(27)13-31-22/h1-7,9-10,12-13,31H,8,11H2,(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283389 (2-((3-chloroquinolin-6-yl)methyl)-N-((6-fluoro- 1H...) Show SMILES Fc1cc2[nH]ccc2cc1CNC(=O)c1ccnc(Cc2ccc3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C25H18ClFN4O/c26-20-10-18-7-15(1-2-23(18)30-14-20)8-21-11-17(4-5-28-21)25(32)31-13-19-9-16-3-6-29-24(16)12-22(19)27/h1-7,9-12,14,29H,8,13H2,(H,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283394 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2ccc3nc(CN)ccc3c2)c1 Show InChI InChI=1S/C25H26N6O/c1-15-9-24(27)30-16(2)22(15)14-29-25(32)19-7-8-28-21(12-19)11-17-3-6-23-18(10-17)4-5-20(13-26)31-23/h3-10,12H,11,13-14,26H2,1-2H3,(H2,27,30)(H,29,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283397 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Fc1cc2[nH]cc(Cl)c2cc1CNC(=O)c1ccnc(Cc2cc(C#N)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C26H16Cl2FN5O/c27-19-6-16-3-14(4-17(10-30)25(16)33-12-19)5-20-7-15(1-2-31-20)26(35)34-11-18-8-21-22(28)13-32-24(21)9-23(18)29/h1-4,6-9,12-13,32H,5,11H2,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283398 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2cc(C#N)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C25H21ClN6O/c1-14-5-23(28)32-15(2)22(14)13-31-25(33)17-3-4-29-21(10-17)8-16-6-18-9-20(26)12-30-24(18)19(7-16)11-27/h3-7,9-10,12H,8,13H2,1-2H3,(H2,28,32)(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283399 (N-((3-chloro-4-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES Fc1c(CNC(=O)c2ccnc(Cc3cc(C#N)c4ncc(Cl)cc4c3)c2)ccc2[nH]cc(Cl)c12 Show InChI InChI=1S/C26H16Cl2FN5O/c27-19-8-17-5-14(6-18(10-30)25(17)33-12-19)7-20-9-15(3-4-31-20)26(35)34-11-16-1-2-22-23(24(16)29)21(28)13-32-22/h1-6,8-9,12-13,32H,7,11H2,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283400 (2-((3-chloro-8-cyanoquinolin-6-yl)methyl)-N- ((6-f...) Show SMILES Fc1cc2[nH]ccc2cc1CNC(=O)c1ccnc(Cc2cc(C#N)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C26H17ClFN5O/c27-21-9-18-5-15(6-19(12-29)25(18)32-14-21)7-22-10-17(2-3-30-22)26(34)33-13-20-8-16-1-4-31-24(16)11-23(20)28/h1-6,8-11,14,31H,7,13H2,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283402 (N-((5-chloro-1H-indazol-3-yl)methyl)-2-((3- chloro...) Show SMILES Clc1ccc2[nH]nc(CNC(=O)c3ccnc(Cc4cc(C#N)c5ncc(Cl)cc5c4)c3)c2c1 Show InChI InChI=1S/C25H16Cl2N6O/c26-18-1-2-22-21(10-18)23(33-32-22)13-31-25(34)15-3-4-29-20(9-15)7-14-5-16-8-19(27)12-30-24(16)17(6-14)11-28/h1-6,8-10,12H,7,13H2,(H,31,34)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283403 (N-((3-chloro-1H-pyrrolo[2,3-b]pyridin-5- yl)methyl...) Show SMILES Clc1c[nH]c2ncc(CNC(=O)c3ccnc(Cc4cc(C#N)c5ncc(Cl)cc5c4)c3)cc12 Show InChI InChI=1S/C25H16Cl2N6O/c26-19-7-17-3-14(4-18(9-28)23(17)30-12-19)5-20-8-16(1-2-29-20)25(34)33-11-15-6-21-22(27)13-32-24(21)31-10-15/h1-4,6-8,10,12-13H,5,11H2,(H,31,32)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283404 (N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((3-ch...) Show SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(Cc2cc(C#N)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C24H19ClN6O/c1-14-17(2-3-22(27)31-14)12-30-24(32)16-4-5-28-21(10-16)8-15-6-18-9-20(25)13-29-23(18)19(7-15)11-26/h2-7,9-10,13H,8,12H2,1H3,(H2,27,31)(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283405 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((3- chloro-...) Show SMILES Nc1nccc2cc(CNC(=O)c3ccnc(Cc4cc(C#N)c5ncc(Cl)cc5c4)c3)ccc12 Show InChI InChI=1S/C27H19ClN6O/c28-22-11-20-8-17(9-21(13-29)25(20)33-15-22)10-23-12-19(4-5-31-23)27(35)34-14-16-1-2-24-18(7-16)3-6-32-26(24)30/h1-9,11-12,15H,10,14H2,(H2,30,32)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283406 (6-((4-(((6-amino-2,4-dimethylpyridin-3- yl)methyl)...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2cc(C(N)=O)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C25H23ClN6O2/c1-13-5-22(27)32-14(2)21(13)12-31-25(34)16-3-4-29-19(10-16)7-15-6-17-9-18(26)11-30-23(17)20(8-15)24(28)33/h3-6,8-11H,7,12H2,1-2H3,(H2,27,32)(H2,28,33)(H,31,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283407 (3-chloro-6-((4-(((3-chloro-6-fluoro-1H-indol-5- yl...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cc3c(Cl)c[nH]c3cc2F)cc2cc(Cl)cnc12 Show InChI InChI=1S/C26H18Cl2FN5O2/c27-17-6-15-3-13(5-20(25(30)35)24(15)33-11-17)4-18-7-14(1-2-31-18)26(36)34-10-16-8-19-21(28)12-32-23(19)9-22(16)29/h1-3,5-9,11-12,32H,4,10H2,(H2,30,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283408 (3-chloro-6-((4-(((5-chloro-1H-indazol-3- yl)methyl...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2n[nH]c3ccc(Cl)cc23)cc2cc(Cl)cnc12 Show InChI InChI=1S/C25H18Cl2N6O2/c26-16-1-2-21-19(10-16)22(33-32-21)12-31-25(35)14-3-4-29-18(9-14)6-13-5-15-8-17(27)11-30-23(15)20(7-13)24(28)34/h1-5,7-11H,6,12H2,(H2,28,34)(H,31,35)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283409 (3-chloro-6-((4-(((3-chloro-1H-pyrrolo[2,3- b]pyrid...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cnc3[nH]cc(Cl)c3c2)cc2cc(Cl)cnc12 Show InChI InChI=1S/C25H18Cl2N6O2/c26-17-7-16-3-13(5-20(23(28)34)22(16)30-11-17)4-18-8-15(1-2-29-18)25(35)33-10-14-6-19-21(27)12-32-24(19)31-9-14/h1-3,5-9,11-12H,4,10H2,(H2,28,34)(H,31,32)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283410 (6-((4-(((6-amino-2-methylpyridin-3- yl)methyl)carb...) Show SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(Cc2cc(C(N)=O)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C24H21ClN6O2/c1-13-16(2-3-21(26)31-13)11-30-24(33)15-4-5-28-19(10-15)7-14-6-17-9-18(25)12-29-22(17)20(8-14)23(27)32/h2-6,8-10,12H,7,11H2,1H3,(H2,26,31)(H2,27,32)(H,30,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283411 (6-((4-(((6-amino-4-methylpyridin-3- yl)methyl)carb...) Show SMILES Cc1cc(N)ncc1CNC(=O)c1ccnc(Cc2cc(C(N)=O)c3ncc(Cl)cc3c2)c1 Show InChI InChI=1S/C24H21ClN6O2/c1-13-4-21(26)29-10-17(13)11-31-24(33)15-2-3-28-19(9-15)6-14-5-16-8-18(25)12-30-22(16)20(7-14)23(27)32/h2-5,7-10,12H,6,11H2,1H3,(H2,26,29)(H2,27,32)(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283412 (6-((4-(((1-aminoisoquinolin-6- yl)methyl)carbamoyl...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2ccc3c(N)nccc3c2)cc2cc(Cl)cnc12 Show InChI InChI=1S/C27H21ClN6O2/c28-20-11-19-8-16(10-23(26(30)35)24(19)33-14-20)9-21-12-18(4-5-31-21)27(36)34-13-15-1-2-22-17(7-15)3-6-32-25(22)29/h1-8,10-12,14H,9,13H2,(H2,29,32)(H2,30,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283413 (3-chloro-6-((4-(((3-chloro-4-fluoro-1H-indol-5- yl...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2ccc3[nH]cc(Cl)c3c2F)cc2cc(Cl)cnc12 Show InChI InChI=1S/C26H18Cl2FN5O2/c27-17-8-16-5-13(7-19(25(30)35)24(16)33-11-17)6-18-9-14(3-4-31-18)26(36)34-10-15-1-2-21-22(23(15)29)20(28)12-32-21/h1-5,7-9,11-12,32H,6,10H2,(H2,30,35)(H,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283414 (3-chloro-6-((4-(((6-fluoro-1H-indol-5- yl)methyl)c...) Show SMILES NC(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cc3cc[nH]c3cc2F)cc2cc(Cl)cnc12 Show InChI InChI=1S/C26H19ClFN5O2/c27-19-9-17-5-14(7-21(25(29)34)24(17)32-13-19)6-20-10-16(2-3-30-20)26(35)33-12-18-8-15-1-4-31-23(15)11-22(18)28/h1-5,7-11,13,31H,6,12H2,(H2,29,34)(H,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283415 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cc(N)nc(C)c1CNC(=O)c1ccnc(Cc2cc(c3ncc(Cl)cc3c2)S(C)(=O)=O)c1 Show InChI InChI=1S/C25H24ClN5O3S/c1-14-6-23(27)31-15(2)21(14)13-30-25(32)17-4-5-28-20(11-17)8-16-7-18-10-19(26)12-29-24(18)22(9-16)35(3,33)34/h4-7,9-12H,8,13H2,1-3H3,(H2,27,31)(H,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283416 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((3...) Show SMILES CS(=O)(=O)c1cc(Cc2cc(ccn2)C(=O)NCc2cc3c(Cl)c[nH]c3cc2F)cc2cc(Cl)cnc12 Show InChI InChI=1S/C26H19Cl2FN4O3S/c1-37(35,36)24-6-14(4-16-7-18(27)12-32-25(16)24)5-19-8-15(2-3-30-19)26(34)33-11-17-9-20-21(28)13-31-23(20)10-22(17)29/h2-4,6-10,12-13,31H,5,11H2,1H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283417 (N-((6-amino-2-methylpyridin-3-yl)methyl)-2- ((3-ch...) Show SMILES Cc1nc(N)ccc1CNC(=O)c1ccnc(Cc2cc(c3ncc(Cl)cc3c2)S(C)(=O)=O)c1 Show InChI InChI=1S/C24H22ClN5O3S/c1-14-17(3-4-22(26)30-14)12-29-24(31)16-5-6-27-20(11-16)8-15-7-18-10-19(25)13-28-23(18)21(9-15)34(2,32)33/h3-7,9-11,13H,8,12H2,1-2H3,(H2,26,30)(H,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283418 (N-((6-amino-2,4-dimethylpyridin-3-yl)methyl)- 2-((...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3c(C)cc(N)nc3C)cc2c1)C#N Show InChI InChI=1S/C26H24N6O/c1-15-6-20-8-18(9-21(12-27)25(20)30-13-15)10-22-11-19(4-5-29-22)26(33)31-14-23-16(2)7-24(28)32-17(23)3/h4-9,11,13H,10,14H2,1-3H3,(H2,28,32)(H,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283419 (N-((1-aminoisoquinolin-6-yl)methyl)-2-((8- cyano-3...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3ccc4c(N)nccc4c3)cc2c1)C#N Show InChI InChI=1S/C28H22N6O/c1-17-8-22-10-19(11-23(14-29)26(22)33-15-17)12-24-13-21(5-6-31-24)28(35)34-16-18-2-3-25-20(9-18)4-7-32-27(25)30/h2-11,13,15H,12,16H2,1H3,(H2,30,32)(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283420 (N-((3-chloro-6-fluoro-1H-indol-5-yl)methyl)-2- ((8...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cc4c(Cl)c[nH]c4cc3F)cc2c1)C#N Show InChI InChI=1S/C27H19ClFN5O/c1-15-4-18-5-16(6-19(11-30)26(18)33-12-15)7-21-8-17(2-3-31-21)27(35)34-13-20-9-22-23(28)14-32-25(22)10-24(20)29/h2-6,8-10,12,14,32H,7,13H2,1H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283421 (N-((3-chloro-1H-pyrrolo[2,3-b]pyridin-5- yl)methyl...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cnc4[nH]cc(Cl)c4c3)cc2c1)C#N Show InChI InChI=1S/C26H19ClN6O/c1-15-4-19-5-16(6-20(10-28)24(19)30-11-15)7-21-9-18(2-3-29-21)26(34)33-13-17-8-22-23(27)14-32-25(22)31-12-17/h2-6,8-9,11-12,14H,7,13H2,1H3,(H,31,32)(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283422 (N-((3-chloro-4-fluoro-1H-indol-5-yl)methyl)-2- ((8...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3ccc4[nH]cc(Cl)c4c3F)cc2c1)C#N Show InChI InChI=1S/C27H19ClFN5O/c1-15-6-19-7-16(8-20(11-30)26(19)33-12-15)9-21-10-17(4-5-31-21)27(35)34-13-18-2-3-23-24(25(18)29)22(28)14-32-23/h2-8,10,12,14,32H,9,13H2,1H3,(H,34,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283423 (N-((5-chloro-1H-indazol-3-yl)methyl)-2-((8- cyano-...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3n[nH]c4ccc(Cl)cc34)cc2c1)C#N Show InChI InChI=1S/C26H19ClN6O/c1-15-6-18-7-16(8-19(12-28)25(18)30-13-15)9-21-10-17(4-5-29-21)26(34)31-14-24-22-11-20(27)2-3-23(22)32-33-24/h2-8,10-11,13H,9,14H2,1H3,(H,31,34)(H,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair
Plasma kallikrein (Homo sapiens (Human))	BDBM283424 (2-((8-cyano-3-methylquinolin-6-yl)methyl)-N- ((6-f...) Show SMILES Cc1cnc2c(cc(Cc3cc(ccn3)C(=O)NCc3cc4cc[nH]c4cc3F)cc2c1)C#N Show InChI InChI=1S/C27H20FN5O/c1-16-6-20-7-17(8-21(13-29)26(20)32-14-16)9-23-11-19(3-4-30-23)27(34)33-15-22-10-18-2-5-31-25(18)12-24(22)28/h2-8,10-12,14,31H,9,15H2,1H3,(H,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<100	n/a	n/a	n/a	n/a	7.5	n/a
LIFESCI PHARMACEUTICALS, INC. US Patent					Assay Description A 10 mM solution of the test compound was made in DMSO. This solution was serially diluted 1:5 in DMSO to yield 2000, 400, 80, 16, 3.2, 0.64, 0.128, ...				US Patent US10023557 (2018) BindingDB Entry DOI: 10.7270/Q2BZ6839
					More data for this Ligand-Target Pair

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