Compile Data Set for Download or QSAR

Found 700 hits Enz. Inhib. hit(s) with all data for entry = 956   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Protein Wnt-3a (Homo sapiens (Human))	BDBM300498 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H24F4N4O4/c28-20-4-2-1-3-19(20)21-7-6-18(16-32-21)33-24(36)17-5-8-23(39-27(29,30)31)22(15-17)34-25(37)26(9-10-26)35-11-13-38-14-12-35/h1-8,15-16H,9-14H2,(H,33,36)(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.17	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300495 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...) Show SMILES C[C@@H](N1CCN(C)CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |r| Show InChI InChI=1S/C27H27F4N5O3/c1-17(36-13-11-35(2)12-14-36)25(37)34-23-15-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-16-19)20-5-3-4-6-21(20)28/h3-10,15-17H,11-14H2,1-2H3,(H,33,38)(H,34,37)/t17-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300498 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1-(morphol...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H24F4N4O4/c28-20-4-2-1-3-19(20)21-7-6-18(16-32-21)33-24(36)17-5-8-23(39-27(29,30)31)22(15-17)34-25(37)26(9-10-26)35-11-13-38-14-12-35/h1-8,15-16H,9-14H2,(H,33,36)(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.72	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300675 (N-[6-(3,5- difluorophenyl)pyridin-3-yl]-3- {[2-(mo...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cc(F)cc(F)c1 Show InChI InChI=1S/C26H23F5N4O4/c1-15(35-6-8-38-9-7-35)24(36)34-22-12-16(2-5-23(22)39-26(29,30)31)25(37)33-20-3-4-21(32-14-20)17-10-18(27)13-19(28)11-17/h2-5,10-15H,6-9H2,1H3,(H,33,37)(H,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.85	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300545 (N-{6-[4-(dimethylamino)phenyl]pyridin-3-yl}-3-{[(2...) Show SMILES C[C@@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(cc1)N(C)C |r| Show InChI InChI=1S/C28H30F3N5O4/c1-18(36-12-14-39-15-13-36)26(37)34-24-16-20(6-11-25(24)40-28(29,30)31)27(38)33-21-7-10-23(32-17-21)19-4-8-22(9-5-19)35(2)3/h4-11,16-18H,12-15H2,1-3H3,(H,33,38)(H,34,37)/t18-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.80	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300439 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(mor...) Show SMILES C[C@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |r| Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-17(6-9-23(22)38-26(28,29)30)25(36)32-18-7-8-21(31-15-18)19-4-2-3-5-20(19)27/h2-9,14-16H,10-13H2,1H3,(H,32,36)(H,33,35)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300440 (3-{[2-(morpholin-4-yl)propanoyl]amino}-N-(6-phenyl...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C26H25F3N4O4/c1-17(33-11-13-36-14-12-33)24(34)32-22-15-19(7-10-23(22)37-26(27,28)29)25(35)31-20-8-9-21(30-16-20)18-5-3-2-4-6-18/h2-10,15-17H,11-14H2,1H3,(H,31,35)(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	10.4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300677 (N-[6-(3-fluorophenyl)pyridin-3- yl]-3-{[2-(8-oxa-3...) Show SMILES CC(N1CC2CCC(C1)O2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1 Show InChI InChI=1S/C28H26F4N4O4/c1-16(36-14-21-7-8-22(15-36)39-21)26(37)35-24-12-18(5-10-25(24)40-28(30,31)32)27(38)34-20-6-9-23(33-13-20)17-3-2-4-19(29)11-17/h2-6,9-13,16,21-22H,7-8,14-15H2,1H3,(H,34,38)(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300496 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(4-m...) Show SMILES C[C@H](N1CCN(C)CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |r| Show InChI InChI=1S/C27H27F4N5O3/c1-17(36-13-11-35(2)12-14-36)25(37)34-23-15-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-16-19)20-5-3-4-6-21(20)28/h3-10,15-17H,11-14H2,1-2H3,(H,33,38)(H,34,37)/t17-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300440 (3-{[2-(morpholin-4-yl)propanoyl]amino}-N-(6-phenyl...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C26H25F3N4O4/c1-17(33-11-13-36-14-12-33)24(34)32-22-15-19(7-10-23(22)37-26(27,28)29)25(35)31-20-8-9-21(30-16-20)18-5-3-2-4-6-18/h2-10,15-17H,11-14H2,1H3,(H,31,35)(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300548 (N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[(2R)-2-(morp...) Show SMILES C[C@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(N)cc1 |r| Show InChI InChI=1S/C26H26F3N5O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(4-9-23(22)38-26(27,28)29)25(36)32-20-7-8-21(31-15-20)17-2-5-19(30)6-3-17/h2-9,14-16H,10-13,30H2,1H3,(H,32,36)(H,33,35)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.6	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300497 (3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]ca...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCN(CC3)C3CC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C30H29F4N5O3/c31-23-4-2-1-3-22(23)24-9-6-20(18-35-24)36-27(40)19-5-10-26(42-30(32,33)34)25(17-19)37-28(41)29(11-12-29)39-15-13-38(14-16-39)21-7-8-21/h1-6,9-10,17-18,21H,7-8,11-16H2,(H,36,40)(H,37,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300436 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-[(8-oxa-3-aza...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)CN3CC4CCC(C3)O4)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H24F4N4O4/c28-21-4-2-1-3-20(21)22-9-6-17(12-32-22)33-26(37)16-5-10-24(39-27(29,30)31)23(11-16)34-25(36)15-35-13-18-7-8-19(14-35)38-18/h1-6,9-12,18-19H,7-8,13-15H2,(H,33,37)(H,34,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300547 (N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[(2R)-2-(morp...) Show SMILES C[C@@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(N)cc1 |r| Show InChI InChI=1S/C26H26F3N5O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(4-9-23(22)38-26(27,28)29)25(36)32-20-7-8-21(31-15-20)17-2-5-19(30)6-3-17/h2-9,14-16H,10-13,30H2,1H3,(H,32,36)(H,33,35)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300439 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[(2S)-2-(mor...) Show SMILES C[C@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |r| Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-17(6-9-23(22)38-26(28,29)30)25(36)32-18-7-8-21(31-15-18)19-4-2-3-5-20(19)27/h2-9,14-16H,10-13H2,1H3,(H,32,36)(H,33,35)/t16-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300499 (N-[6-(3-fluorophenyl)pyridin-3-yl]-3-{[2-(morpholi...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-9-11-37-12-10-34)24(35)33-22-14-18(5-8-23(22)38-26(28,29)30)25(36)32-20-6-7-21(31-15-20)17-3-2-4-19(27)13-17/h2-8,13-16H,9-12H2,1H3,(H,32,36)(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	14.8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300511 (4-methoxy-3-({[1-(morpholin-4-yl)cyclopropyl]carbo...) Show SMILES COc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C27H28N4O4/c1-34-24-10-7-20(17-23(24)30-26(33)27(11-12-27)31-13-15-35-16-14-31)25(32)29-21-8-9-22(28-18-21)19-5-3-2-4-6-19/h2-10,17-18H,11-16H2,1H3,(H,29,32)(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300564 (4-(cyclopropyloxy)-N-[6-(2-fluorophenyl)pyridin-3-...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC3CC3)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H29FN4O4/c30-23-4-2-1-3-22(23)24-9-6-20(18-31-24)32-27(35)19-5-10-26(38-21-7-8-21)25(17-19)33-28(36)29(11-12-29)34-13-15-37-16-14-34/h1-6,9-10,17-18,21H,7-8,11-16H2,(H,32,35)(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	16.6	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300687 (N-[5-(2-methylphenyl)-1,3,4- thiadiazol-2-yl]-3-({...) Show SMILES Cc1ccccc1-c1nnc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)s1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C25H24F3N5O4S/c1-15-4-2-3-5-17(15)21-31-32-23(38-21)30-20(34)16-6-7-19(37-25(26,27)28)18(14-16)29-22(35)24(8-9-24)33-10-12-36-13-11-33/h2-7,14H,8-13H2,1H3,(H,29,35)(H,30,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300446 (N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromet...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2ncc(s2)-c2ccccc2)cc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C23H21F3N4O4S/c24-23(25,26)34-18-7-6-16(12-17(18)29-20(31)14-30-8-10-33-11-9-30)28-21(32)22-27-13-19(35-22)15-4-2-1-3-5-15/h1-7,12-13H,8-11,14H2,(H,28,32)(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	17.8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300547 (N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[(2R)-2-(morp...) Show SMILES C[C@@H](N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(N)cc1 |r| Show InChI InChI=1S/C26H26F3N5O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(4-9-23(22)38-26(27,28)29)25(36)32-20-7-8-21(31-15-20)17-2-5-19(30)6-3-17/h2-9,14-16H,10-13,30H2,1H3,(H,32,36)(H,33,35)/t16-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300505 (N4-[6-(2-fluorophenyl)pyridin-3-yl]-2-({[1-(morpho...) Show SMILES NC(=O)c1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H26FN5O4/c28-21-4-2-1-3-19(21)22-8-6-18(16-30-22)31-25(35)17-5-7-20(24(29)34)23(15-17)32-26(36)27(9-10-27)33-11-13-37-14-12-33/h1-8,15-16H,9-14H2,(H2,29,34)(H,31,35)(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	18.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300490 (6-(3,5-difluorophenyl)-N-[3-({[1-(morpholin-4-yl)c...) Show SMILES Fc1cc(F)cc(c1)-c1ccc(cn1)C(=O)Nc1ccc(OC(F)(F)F)c(NC(=O)C2(CC2)N2CCOCC2)c1 Show InChI InChI=1S/C27H23F5N4O4/c28-18-11-17(12-19(29)13-18)21-3-1-16(15-33-21)24(37)34-20-2-4-23(40-27(30,31)32)22(14-20)35-25(38)26(5-6-26)36-7-9-39-10-8-36/h1-4,11-15H,5-10H2,(H,34,37)(H,35,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300634 (6-(2-fluorophenyl)-N-[3-{[2-(8- oxa-3-azabicyclo[3...) Show SMILES CC(N1CC2CCC(C1)O2)C(=O)Nc1cc(NC(=O)c2ccc(nc2)-c2ccccc2F)ccc1OC(F)(F)F Show InChI InChI=1S/C28H26F4N4O4/c1-16(36-14-19-8-9-20(15-36)39-19)26(37)35-24-12-18(7-11-25(24)40-28(30,31)32)34-27(38)17-6-10-23(33-13-17)21-4-2-3-5-22(21)29/h2-7,10-13,16,19-20H,8-9,14-15H2,1H3,(H,34,38)(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300509 (4-chloro-N-[6-(2-fluorophenyl)pyridin-3-yl]-3-({[1...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(Cl)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C26H24ClFN4O3/c27-20-7-5-17(15-23(20)31-25(34)26(9-10-26)32-11-13-35-14-12-32)24(33)30-18-6-8-22(29-16-18)19-3-1-2-4-21(19)28/h1-8,15-16H,9-14H2,(H,30,33)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300467 (4-(difluoromethoxy)-3-({[1-(morpholin-4-yl)cyclopr...) Show SMILES FC(F)Oc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1nnc(s1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C24H23F2N5O4S/c25-22(26)35-18-7-6-16(19(32)28-23-30-29-20(36-23)15-4-2-1-3-5-15)14-17(18)27-21(33)24(8-9-24)31-10-12-34-13-11-31/h1-7,14,22H,8-13H2,(H,27,33)(H,28,30,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	20.8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300566 (4-(cyclopropyloxy)-3-({[1-(4-cyclopropylpiperazin-...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC3CC3)c(NC(=O)C3(CC3)N3CCN(CC3)C3CC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C32H34FN5O3/c33-26-4-2-1-3-25(26)27-11-6-22(20-34-27)35-30(39)21-5-12-29(41-24-9-10-24)28(19-21)36-31(40)32(13-14-32)38-17-15-37(16-18-38)23-7-8-23/h1-6,11-12,19-20,23-24H,7-10,13-18H2,(H,35,39)(H,36,40)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	21.4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300494 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[2-(4-methyl...) Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H27F4N5O3/c1-17(36-13-11-35(2)12-14-36)25(37)34-23-15-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-16-19)20-5-3-4-6-21(20)28/h3-10,15-17H,11-14H2,1-2H3,(H,33,38)(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300543 (N-[6-(4-acetamidophenyl)pyridin-3-yl]-3-{[2-(morph...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(NC(C)=O)cc1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C28H28F3N5O5/c1-17(36-11-13-40-14-12-36)26(38)35-24-15-20(5-10-25(24)41-28(29,30)31)27(39)34-22-8-9-23(32-16-22)19-3-6-21(7-4-19)33-18(2)37/h3-10,15-17H,11-14H2,1-2H3,(H,33,37)(H,34,39)(H,35,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300511 (4-methoxy-3-({[1-(morpholin-4-yl)cyclopropyl]carbo...) Show SMILES COc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;$| Show InChI InChI=1S/C27H28N4O4/c1-34-24-10-7-20(17-23(24)30-26(33)27(11-12-27)31-13-15-35-16-14-31)25(32)29-21-8-9-22(28-18-21)19-5-3-2-4-6-19/h2-10,17-18H,11-16H2,1H3,(H,29,32)(H,30,33)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.1	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300437 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[2-(morpholi...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-17(6-9-23(22)38-26(28,29)30)25(36)32-18-7-8-21(31-15-18)19-4-2-3-5-20(19)27/h2-9,14-16H,10-13H2,1H3,(H,32,36)(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	23.7	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300500 (N-[6-(3-fluorophenyl)pyridin-3-yl]-3-{[2-(8-oxa-3-...) Show SMILES CC(N1CC2CCC(C1)O2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1 |$;;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C28H26F4N4O4/c1-16(36-14-21-7-8-22(15-36)39-21)26(37)35-24-12-18(5-10-25(24)40-28(30,31)32)27(38)34-20-6-9-23(33-13-20)17-3-2-4-19(29)11-17/h2-6,9-13,16,21-22H,7-8,14-15H2,1H3,(H,34,38)(H,35,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300449 (N-{4-tert-butyl-3-[(morpholin-4-ylacetyl)amino]phe...) Show SMILES CC(C)(C)c1ccc(NC(=O)c2ccc(s2)-c2ccccc2)cc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C27H31N3O3S/c1-27(2,3)21-10-9-20(17-22(21)29-25(31)18-30-13-15-33-16-14-30)28-26(32)24-12-11-23(34-24)19-7-5-4-6-8-19/h4-12,17H,13-16,18H2,1-3H3,(H,28,32)(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300482 (3-({[1-(4-methylpiperazin-1-yl)cyclopropyl]carbony...) Show SMILES CN1CCN(CC1)C1(CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1nnc(s1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C25H25F3N6O3S/c1-33-11-13-34(14-12-33)24(9-10-24)22(36)29-18-15-17(7-8-19(18)37-25(26,27)28)20(35)30-23-32-31-21(38-23)16-5-3-2-4-6-16/h2-8,15H,9-14H2,1H3,(H,29,36)(H,30,32,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300491 (N-[3-({[1-(morpholin-4-yl)cyclopropyl]carbonyl}ami...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2ccc(nc2)-c2ccccc2)cc1NC(=O)C1(CC1)N1CCOCC1 Show InChI InChI=1S/C27H25F3N4O4/c28-27(29,30)38-23-9-7-20(16-22(23)33-25(36)26(10-11-26)34-12-14-37-15-13-34)32-24(35)19-6-8-21(31-17-19)18-4-2-1-3-5-18/h1-9,16-17H,10-15H2,(H,32,35)(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300510 (N-[6-(2-fluorophenyl)pyridin-3-yl]-4-methoxy-3-({[...) Show SMILES COc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H27FN4O4/c1-35-24-9-6-18(16-23(24)31-26(34)27(10-11-27)32-12-14-36-15-13-32)25(33)30-19-7-8-22(29-17-19)20-4-2-3-5-21(20)28/h2-9,16-17H,10-15H2,1H3,(H,30,33)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300505 (N4-[6-(2-fluorophenyl)pyridin-3-yl]-2-({[1-(morpho...) Show SMILES NC(=O)c1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H26FN5O4/c28-21-4-2-1-3-19(21)22-8-6-18(16-30-22)31-25(35)17-5-7-20(24(29)34)23(15-17)32-26(36)27(9-10-27)33-11-13-37-14-12-33/h1-8,15-16H,9-14H2,(H2,29,34)(H,31,35)(H,32,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300468 (3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]ca...) Show SMILES FC(F)Oc1ccc(cc1NC(=O)C1(CC1)N1CCN(CC1)C1CC1)C(=O)Nc1nnc(s1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C27H28F2N6O3S/c28-25(29)38-21-9-6-18(22(36)31-26-33-32-23(39-26)17-4-2-1-3-5-17)16-20(21)30-24(37)27(10-11-27)35-14-12-34(13-15-35)19-7-8-19/h1-6,9,16,19,25H,7-8,10-15H2,(H,30,37)(H,31,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	27.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300673 (N-[6-(3-fluorophenyl)pyridin-3- yl]-3-({(2R*)-2-[(...) Show SMILES CC(N1C[C@@H]2C[C@H]1CO2)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1 |r| Show InChI InChI=1S/C27H24F4N4O4/c1-15(35-13-21-11-20(35)14-38-21)25(36)34-23-10-17(5-8-24(23)39-27(29,30)31)26(37)33-19-6-7-22(32-12-19)16-3-2-4-18(28)9-16/h2-10,12,15,20-21H,11,13-14H2,1H3,(H,33,37)(H,34,36)/t15?,20-,21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300612 (N-[6-(3-fluorophenyl)pyridin-3- yl]-3-{[2-(morphol...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1cccc(F)c1 Show InChI InChI=1S/C26H24F4N4O4/c1-16(34-9-11-37-12-10-34)24(35)33-22-14-18(5-8-23(22)38-26(28,29)30)25(36)32-20-6-7-21(31-15-20)17-3-2-4-19(27)13-17/h2-8,13-16H,9-12H2,1H3,(H,32,36)(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300501 (N-[6-(3,5-difluorophenyl)pyridin-3-yl]-3-({[1-(mor...) Show SMILES Fc1cc(F)cc(c1)-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H23F5N4O4/c28-18-11-17(12-19(29)14-18)21-3-2-20(15-33-21)34-24(37)16-1-4-23(40-27(30,31)32)22(13-16)35-25(38)26(5-6-26)36-7-9-39-10-8-36/h1-4,11-15H,5-10H2,(H,34,37)(H,35,38)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300497 (3-({[1-(4-cyclopropylpiperazin-1-yl)cyclopropyl]ca...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)C3(CC3)N3CCN(CC3)C3CC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C30H29F4N5O3/c31-23-4-2-1-3-22(23)24-9-6-20(18-35-24)36-27(40)19-5-10-26(42-30(32,33)34)25(17-19)37-28(41)29(11-12-29)39-15-13-38(14-16-39)21-7-8-21/h1-6,9-10,17-18,21H,7-8,11-16H2,(H,36,40)(H,37,41)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	29.6	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300564 (4-(cyclopropyloxy)-N-[6-(2-fluorophenyl)pyridin-3-...) Show SMILES Fc1ccccc1-c1ccc(NC(=O)c2ccc(OC3CC3)c(NC(=O)C3(CC3)N3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C29H29FN4O4/c30-23-4-2-1-3-22(23)24-9-6-20(18-31-24)32-27(35)19-5-10-26(38-21-7-8-21)25(17-19)33-28(36)29(11-12-29)34-13-15-37-16-14-34/h1-6,9-10,17-18,21H,7-8,11-16H2,(H,32,35)(H,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300506 (N-[6-(2-fluorophenyl)pyridin-3-yl]-4-methyl-3-({[1...) Show SMILES Cc1ccc(cc1NC(=O)C1(CC1)N1CCOCC1)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H27FN4O3/c1-18-6-7-19(16-24(18)31-26(34)27(10-11-27)32-12-14-35-15-13-32)25(33)30-20-8-9-23(29-17-20)21-4-2-3-5-22(21)28/h2-9,16-17H,10-15H2,1H3,(H,30,33)(H,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	31.4	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300541 (N-[6-(4-aminophenyl)pyridin-3-yl]-3-{[2-(morpholin...) Show SMILES CC(N1CCOCC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccc(N)cc1 |$;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C26H26F3N5O4/c1-16(34-10-12-37-13-11-34)24(35)33-22-14-18(4-9-23(22)38-26(27,28)29)25(36)32-20-7-8-21(31-15-20)17-2-5-19(30)6-3-17/h2-9,14-16H,10-13,30H2,1H3,(H,32,36)(H,33,35)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	32.2	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300447 (N-{3-[(morpholin-4-ylacetyl)amino]-4-(trifluoromet...) Show SMILES FC(F)(F)Oc1ccc(NC(=O)c2ccc(s2)-c2ccccc2)cc1NC(=O)CN1CCOCC1 Show InChI InChI=1S/C24H22F3N3O4S/c25-24(26,27)34-19-7-6-17(14-18(19)29-22(31)15-30-10-12-33-13-11-30)28-23(32)21-9-8-20(35-21)16-4-2-1-3-5-16/h1-9,14H,10-13,15H2,(H,28,32)(H,29,31)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300469 (4-(difluoromethoxy)-3-({[1-(4-methylpiperazin-1-yl...) Show SMILES CN1CCN(CC1)C1(CC1)C(=O)Nc1cc(ccc1OC(F)F)C(=O)Nc1nnc(s1)-c1ccccc1 |$;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;$| Show InChI InChI=1S/C25H26F2N6O3S/c1-32-11-13-33(14-12-32)25(9-10-25)22(35)28-18-15-17(7-8-19(18)36-23(26)27)20(34)29-24-31-30-21(37-24)16-5-3-2-4-6-16/h2-8,15,23H,9-14H2,1H3,(H,28,35)(H,29,31,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	33.8	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300562 (3-{[(4-methylpiperazin-1-yl)acetyl]amino}-N-(5-phe...) Show SMILES CC1CCN(CC(=O)Nc2cc(ccc2OC(F)(F)F)C(=O)Nc2ccc(cn2)-c2ccccc2)CC1 |$;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H27F3N4O3/c1-18-11-13-34(14-12-18)17-25(35)32-22-15-20(7-9-23(22)37-27(28,29)30)26(36)33-24-10-8-21(16-31-24)19-5-3-2-4-6-19/h2-10,15-16,18H,11-14,17H2,1H3,(H,32,35)(H,31,33,36)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	35.5	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before at 10000 cells per well of a 384 micro titre plate (MTP) in 30 μL gr...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300556 (N-[6-(4-aminophenyl)pyridin-3-yl]-3-[(morpholin-4-...) Show SMILES Nc1ccc(cc1)-c1ccc(NC(=O)c2ccc(OC(F)(F)F)c(NC(=O)CN3CCOCC3)c2)cn1 |$;;;;;;;;;;;HN;;;;;;;;;;;;;;;;;;;;;;;;;$| Show InChI InChI=1S/C25H24F3N5O4/c26-25(27,28)37-22-8-3-17(13-21(22)32-23(34)15-33-9-11-36-12-10-33)24(35)31-19-6-7-20(30-14-19)16-1-4-18(29)5-2-16/h1-8,13-14H,9-12,15,29H2,(H,31,35)(H,32,34)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	36	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair
Protein Wnt-3a (Homo sapiens (Human))	BDBM300494 (N-[6-(2-fluorophenyl)pyridin-3-yl]-3-{[2-(4-methyl...) Show SMILES CC(N1CCN(C)CC1)C(=O)Nc1cc(ccc1OC(F)(F)F)C(=O)Nc1ccc(nc1)-c1ccccc1F |$;;;;;;;;;;;;;;;;;;;;;;;;;HN;;;;;;;;;;;;;$| Show InChI InChI=1S/C27H27F4N5O3/c1-17(36-13-11-35(2)12-14-36)25(37)34-23-15-18(7-10-24(23)39-27(29,30)31)26(38)33-19-8-9-22(32-16-19)20-5-3-4-6-21(20)28/h3-10,15-17H,11-14H2,1-2H3,(H,33,38)(H,34,37)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
BAYER PHARMA AKTIENGESELLSCHAFT US Patent					Assay Description In preparation of the assay, the two cell lines were plated 24 hours before beginning the test at 10000 cells per well in a 384 micro titre plate (MT...				US Patent US10130633 (2018) BindingDB Entry DOI: 10.7270/Q2FN188G
					More data for this Ligand-Target Pair

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