Compile Data Set for Download or QSAR

Found 488 hits Enz. Inhib. hit(s) with all data for entry = 3049   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293415 (US10106527, Compound 1 | US10106527, Compound 145 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cn[nH]c1 Show InChI InChI=1S/C23H23N7O/c1-29-6-8-30(9-7-29)22-12-17(4-5-24-22)23(31)28-21-11-19-10-16(20-14-26-27-15-20)2-3-18(19)13-25-21/h2-5,10-15H,6-9H2,1H3,(H,26,27)(H,25,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.35E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293416 (US10106527, Compound 2 | US10544128, Compound 2 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3cccc(c3)N3CCNCC3)cc2c1 Show InChI InChI=1S/C24H24N6O/c1-29-16-21(15-27-29)17-5-6-19-14-26-23(13-20(19)11-17)28-24(31)18-3-2-4-22(12-18)30-9-7-25-8-10-30/h2-6,11-16,25H,7-10H2,1H3,(H,26,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.69E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293417 (US10106527, Compound 3 | US10544128, Compound 3 | ...) Show SMILES CN1CCN(CC1)c1cccc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6O/c1-29-8-10-31(11-9-29)23-5-3-4-19(13-23)25(32)28-24-14-21-12-18(6-7-20(21)15-26-24)22-16-27-30(2)17-22/h3-7,12-17H,8-11H2,1-2H3,(H,26,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.73E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293418 (US10106527, Compound 4 | US10544128, Compound 4 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3cccc(CN4CCCC4)c3)cc2c1 Show InChI InChI=1S/C25H25N5O/c1-29-17-23(15-27-29)19-7-8-21-14-26-24(13-22(21)12-19)28-25(31)20-6-4-5-18(11-20)16-30-9-2-3-10-30/h4-8,11-15,17H,2-3,9-10,16H2,1H3,(H,26,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.07E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293419 (US10106527, Compound 5 | US10544128, Compound 5 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3cccc(OC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C25H25N5O2/c1-30-16-21(15-28-30)17-5-6-19-14-27-24(13-20(19)11-17)29-25(31)18-3-2-4-23(12-18)32-22-7-9-26-10-8-22/h2-6,11-16,22,26H,7-10H2,1H3,(H,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.25E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293420 (US10106527, Compound 6 | US10544128, Compound 6 | ...) Show SMILES CN1CCC(CC1)Oc1cccc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H27N5O2/c1-30-10-8-23(9-11-30)33-24-5-3-4-19(13-24)26(32)29-25-14-21-12-18(6-7-20(21)15-27-25)22-16-28-31(2)17-22/h3-7,12-17,23H,8-11H2,1-2H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.93E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293421 (US10106527, Compound 7 | US10544128, Compound 7 | ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccc(OC4CCNCC4)cc3)cc2c1 Show InChI InChI=1S/C25H25N5O2/c1-30-16-21(15-28-30)18-2-3-19-14-27-24(13-20(19)12-18)29-25(31)17-4-6-22(7-5-17)32-23-8-10-26-11-9-23/h2-7,12-16,23,26H,8-11H2,1H3,(H,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	330	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293422 (US10106527, Compound 8 | US10544128, Compound 8 | ...) Show SMILES CN1CCC(CC1)Oc1ccc(cc1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H27N5O2/c1-30-11-9-24(10-12-30)33-23-7-5-18(6-8-23)26(32)29-25-14-21-13-19(3-4-20(21)15-27-25)22-16-28-31(2)17-22/h3-8,13-17,24H,9-12H2,1-2H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	668	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293423 (US10106527, Compound 461 | US10106527, Compound 9 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCNCC3)cc2c1 Show InChI InChI=1S/C23H23N7O/c1-29-15-20(14-27-29)16-2-3-18-13-26-21(11-19(18)10-16)28-23(31)17-4-5-25-22(12-17)30-8-6-24-7-9-30/h2-5,10-15,24H,6-9H2,1H3,(H,26,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.40E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293424 (US10106527, Compound 10 | US10106527, Compound 142...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-25-23)24(32)28-22-12-20-11-17(3-4-19(20)14-26-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,26,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293425 (US10106527, Compound 11 | US10544128, Compound 11 ...) Show SMILES CC(C)N1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H29N7O/c1-18(2)32-8-10-33(11-9-32)25-14-20(6-7-27-25)26(34)30-24-13-22-12-19(4-5-21(22)15-28-24)23-16-29-31(3)17-23/h4-7,12-18H,8-11H2,1-3H3,(H,28,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.90E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293426 (US10106527, Compound 12 | US10544128, Compound 12 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(CC3)C3CC3)cc2c1 Show InChI InChI=1S/C26H27N7O/c1-31-17-22(16-29-31)18-2-3-20-15-28-24(13-21(20)12-18)30-26(34)19-6-7-27-25(14-19)33-10-8-32(9-11-33)23-4-5-23/h2-3,6-7,12-17,23H,4-5,8-11H2,1H3,(H,28,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.03E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293427 (US10106527, Compound 13 | US10544128, Compound 13 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCN(CCF)CC3)cc2c1 Show InChI InChI=1S/C25H26FN7O/c1-31-17-22(16-29-31)18-2-3-20-15-28-23(13-21(20)12-18)30-25(34)19-4-6-27-24(14-19)33-10-8-32(7-5-26)9-11-33/h2-4,6,12-17H,5,7-11H2,1H3,(H,28,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.27E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293428 (US10106527, Compound 14 | US10544128, Compound 14 ...) Show SMILES CN1CCN(CC1)c1ccc(cn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-6-5-19(14-26-23)24(32)28-22-12-20-11-17(3-4-18(20)13-25-22)21-15-27-30(2)16-21/h3-6,11-16H,7-10H2,1-2H3,(H,25,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	479	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293429 (US10106527, Compound 15 | US10544128, Compound 15 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3cncc(OC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C24H24N6O2/c1-30-15-20(13-28-30)16-2-3-17-12-27-23(10-18(17)8-16)29-24(31)19-9-22(14-26-11-19)32-21-4-6-25-7-5-21/h2-3,8-15,21,25H,4-7H2,1H3,(H,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293430 (US10106527, Compound 16 | US10544128, Compound 16 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(OC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C24H24N6O2/c1-30-15-20(14-28-30)16-2-3-18-13-27-22(11-19(18)10-16)29-24(31)17-4-9-26-23(12-17)32-21-5-7-25-8-6-21/h2-4,9-15,21,25H,5-8H2,1H3,(H,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.26E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293431 (US10106527, Compound 17 | US10544128, Compound 17 ...) Show SMILES CN1CCC(CC1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H26N6O2/c1-30-9-6-22(7-10-30)33-24-13-18(5-8-26-24)25(32)29-23-12-20-11-17(3-4-19(20)14-27-23)21-15-28-31(2)16-21/h3-5,8,11-16,22H,6-7,9-10H2,1-2H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.53E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293432 (US10106527, Compound 18 | US10544128, Compound 18 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3cncc(NC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C24H25N7O/c1-31-15-20(13-28-31)16-2-3-17-12-27-23(10-18(17)8-16)30-24(32)19-9-22(14-26-11-19)29-21-4-6-25-7-5-21/h2-3,8-15,21,25,29H,4-7H2,1H3,(H,27,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.76E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293433 (US10106527, Compound 19 | US10544128, Compound 19 ...) Show SMILES CN1CCC(CC1)Nc1cncc(c1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-31-7-5-22(6-8-31)29-23-10-20(12-26-15-23)25(33)30-24-11-19-9-17(3-4-18(19)13-27-24)21-14-28-32(2)16-21/h3-4,9-16,22,29H,5-8H2,1-2H3,(H,27,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.03E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293434 (US10106527, Compound 20 | US10544128, Compound 20 ...) Show SMILES CC(C)n1cc(cn1)-c1ccc2cnc(NC(=O)c3cccc(OC4CCNCC4)c3)cc2c1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)32-17-23(16-30-32)19-6-7-21-15-29-26(14-22(21)12-19)31-27(33)20-4-3-5-25(13-20)34-24-8-10-28-11-9-24/h3-7,12-18,24,28H,8-11H2,1-2H3,(H,29,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293435 (US10106527, Compound 21 | US10544128, Compound 21 ...) Show SMILES CC(C)n1cc(cn1)-c1ccc2cnc(NC(=O)c3cccc(OC4CCN(C)CC4)c3)cc2c1 Show InChI InChI=1S/C28H31N5O2/c1-19(2)33-18-24(17-30-33)20-7-8-22-16-29-27(15-23(22)13-20)31-28(34)21-5-4-6-26(14-21)35-25-9-11-32(3)12-10-25/h4-8,13-19,25H,9-12H2,1-3H3,(H,29,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293436 (US10106527, Compound 22 | US10544128, Compound 22 ...) Show SMILES CC(C)n1cc(cn1)-c1ccc2cnc(NC(=O)c3ccc(OC4CCNCC4)cc3)cc2c1 Show InChI InChI=1S/C27H29N5O2/c1-18(2)32-17-23(16-30-32)20-3-4-21-15-29-26(14-22(21)13-20)31-27(33)19-5-7-24(8-6-19)34-25-9-11-28-12-10-25/h3-8,13-18,25,28H,9-12H2,1-2H3,(H,29,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293437 (US10106527, Compound 23 | US10544128, Compound 23 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(c1)C1CC1 Show InChI InChI=1S/C26H27N7O/c1-31-8-10-32(11-9-31)25-14-19(6-7-27-25)26(34)30-24-13-21-12-18(2-3-20(21)15-28-24)22-16-29-33(17-22)23-4-5-23/h2-3,6-7,12-17,23H,4-5,8-11H2,1H3,(H,28,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293438 (US10106527, Compound 24 | US10544128, Compound 24 ...) Show SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2cnc(NC(=O)c3ccc(F)cc3)cc2c1 Show InChI InChI=1S/C25H24FN5O/c1-30-10-8-23(9-11-30)31-16-21(15-28-31)18-2-3-19-14-27-24(13-20(19)12-18)29-25(32)17-4-6-22(26)7-5-17/h2-7,12-16,23H,8-11H2,1H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293439 (US10106527, Compound 25 | US10544128, Compound 25 ...) Show SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2cnc(NC(=O)c3ccc(OC(F)F)cc3)cc2c1 Show InChI InChI=1S/C26H25F2N5O2/c1-32-10-8-22(9-11-32)33-16-21(15-30-33)18-2-3-19-14-29-24(13-20(19)12-18)31-25(34)17-4-6-23(7-5-17)35-26(27)28/h2-7,12-16,22,26H,8-11H2,1H3,(H,29,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293440 (US10106527, Compound 26 | US10544128, Compound 26 ...) Show SMILES CN1CCC(CC1)n1cc(cn1)-c1ccc2cnc(NC(=O)c3cncc(F)c3)cc2c1 Show InChI InChI=1S/C24H23FN6O/c1-30-6-4-22(5-7-30)31-15-20(13-28-31)16-2-3-17-12-27-23(10-18(17)8-16)29-24(32)19-9-21(25)14-26-11-19/h2-3,8-15,22H,4-7H2,1H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293441 (US10106527, Compound 27 | US10544128, Compound 27 ...) Show SMILES CNC(=O)c1ccc(cn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(c1)C1CCN(C)CC1 Show InChI InChI=1S/C26H27N7O2/c1-27-26(35)23-6-5-19(14-28-23)25(34)31-24-12-20-11-17(3-4-18(20)13-29-24)21-15-30-33(16-21)22-7-9-32(2)10-8-22/h3-6,11-16,22H,7-10H2,1-2H3,(H,27,35)(H,29,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293442 (US10106527, Compound 28 | US10544128, Compound 28 ...) Show SMILES Cn1cncc1-c1ccc2cnc(NC(=O)c3ccc(F)cc3)cc2c1 Show InChI InChI=1S/C20H15FN4O/c1-25-12-22-11-18(25)14-2-3-15-10-23-19(9-16(15)8-14)24-20(26)13-4-6-17(21)7-5-13/h2-12H,1H3,(H,23,24,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	537	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293443 (US10106527, Compound 29 | US10544128, Compound 29 ...) Show SMILES Cn1cncc1-c1ccc2cnc(NC(=O)c3ccc(OC(F)F)cc3)cc2c1 Show InChI InChI=1S/C21H16F2N4O2/c1-27-12-24-11-18(27)14-2-3-15-10-25-19(9-16(15)8-14)26-20(28)13-4-6-17(7-5-13)29-21(22)23/h2-12,21H,1H3,(H,25,26,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	818	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293444 (US10106527, Compound 37 | US10544128, Compound 37 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cncn1C Show InChI InChI=1S/C24H25N7O/c1-29-7-9-31(10-8-29)23-13-18(5-6-26-23)24(32)28-22-12-20-11-17(3-4-19(20)14-27-22)21-15-25-16-30(21)2/h3-6,11-16H,7-10H2,1-2H3,(H,27,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.52E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293445 (US10106527, Compound 40 | US10544128, Compound 40 ...) Show SMILES CC(C)Oc1ccc(cc1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnc(C)n1C Show InChI InChI=1S/C24H24N4O2/c1-15(2)30-21-9-7-17(8-10-21)24(29)27-23-12-20-11-18(5-6-19(20)13-26-23)22-14-25-16(3)28(22)4/h5-15H,1-4H3,(H,26,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293446 (US10106527, Compound 45 | US10544128, Compound 45 ...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)c4ccc(OC5CCNCC5)cc4)cc3c2)n1C Show InChI InChI=1S/C26H27N5O2/c1-17-28-16-24(31(17)2)19-3-4-20-15-29-25(14-21(20)13-19)30-26(32)18-5-7-22(8-6-18)33-23-9-11-27-12-10-23/h3-8,13-16,23,27H,9-12H2,1-2H3,(H,29,30,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.88E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293447 (US10106527, Compound 47 | US10544128, Compound 47 ...) Show SMILES Cc1ncc(-c2ccc3cnc(NC(=O)c4ccc(OCc5ccccc5)cc4)cc3c2)n1C Show InChI InChI=1S/C28H24N4O2/c1-19-29-17-26(32(19)2)22-8-9-23-16-30-27(15-24(23)14-22)31-28(33)21-10-12-25(13-11-21)34-18-20-6-4-3-5-7-20/h3-17H,18H2,1-2H3,(H,30,31,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293448 (US10106527, Compound 49 | US10544128, Compound 49 ...) Show SMILES CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnc(C)n1C Show InChI InChI=1S/C25H27N7O/c1-17-27-16-22(31(17)3)18-4-5-20-15-28-23(13-21(20)12-18)29-25(33)19-6-7-26-24(14-19)32-10-8-30(2)9-11-32/h4-7,12-16H,8-11H2,1-3H3,(H,28,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293449 (US10106527, Compound 52 | US10544128, Compound 52 ...) Show SMILES CC(C)Oc1ccc(cc1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnc2CNCCn12 Show InChI InChI=1S/C25H25N5O2/c1-16(2)32-21-7-5-17(6-8-21)25(31)29-23-12-20-11-18(3-4-19(20)13-27-23)22-14-28-24-15-26-9-10-30(22)24/h3-8,11-14,16,26H,9-10,15H2,1-2H3,(H,27,29,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.32E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293450 (US10106527, Compound 53 | US10544128, Compound 53 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCC(N)CC3)cc2c1 Show InChI InChI=1S/C24H25N7O/c1-30-15-20(14-28-30)16-2-3-18-13-27-22(11-19(18)10-16)29-24(32)17-4-7-26-23(12-17)31-8-5-21(25)6-9-31/h2-4,7,10-15,21H,5-6,8-9,25H2,1H3,(H,27,29,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	859	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293451 (US10106527, Compound 54 | US10544128, Compound 54 ...) Show SMILES CNC1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-26-22-6-9-32(10-7-22)24-13-18(5-8-27-24)25(33)30-23-12-20-11-17(3-4-19(20)14-28-23)21-15-29-31(2)16-21/h3-5,8,11-16,22,26H,6-7,9-10H2,1-2H3,(H,28,30,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.42E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293452 (US10106527, Compound 55 | US10544128, Compound 55 ...) Show SMILES CN(C)C1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C26H29N7O/c1-31(2)23-7-10-33(11-8-23)25-14-19(6-9-27-25)26(34)30-24-13-21-12-18(4-5-20(21)15-28-24)22-16-29-32(3)17-22/h4-6,9,12-17,23H,7-8,10-11H2,1-3H3,(H,28,30,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293453 (US10106527, Compound 56 | US10544128, Compound 56 ...) Show SMILES CC(C)N1CCC(CC1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C27H30N6O2/c1-18(2)33-10-7-24(8-11-33)35-26-14-20(6-9-28-26)27(34)31-25-13-22-12-19(4-5-21(22)15-29-25)23-16-30-32(3)17-23/h4-6,9,12-18,24H,7-8,10-11H2,1-3H3,(H,29,31,34)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.97E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293454 (US10106527, Compound 57 | US10544128, Compound 57 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CC(N)C3)cc2c1 Show InChI InChI=1S/C22H21N7O/c1-28-11-18(10-26-28)14-2-3-16-9-25-20(7-17(16)6-14)27-22(30)15-4-5-24-21(8-15)29-12-19(23)13-29/h2-11,19H,12-13,23H2,1H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.04E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293455 (US10106527, Compound 59 | US10544128, Compound 59 ...) Show SMILES CN(C)C1CN(C1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C24H25N7O/c1-29(2)21-14-31(15-21)23-10-17(6-7-25-23)24(32)28-22-9-19-8-16(4-5-18(19)11-26-22)20-12-27-30(3)13-20/h4-13,21H,14-15H2,1-3H3,(H,26,28,32)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.86E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293456 (US10106527, Compound 60 | US10544128, Compound 60 ...) Show SMILES Cn1cc(nn1)-c1ccc2cnc(NC(=O)c3ccccc3F)cc2c1 Show InChI InChI=1S/C19H14FN5O/c1-25-11-17(23-24-25)12-6-7-13-10-21-18(9-14(13)8-12)22-19(26)15-4-2-3-5-16(15)20/h2-11H,1H3,(H,21,22,26)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	439	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293457 (US10106527, Compound 61 | US10544128, Compound 61 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(c3)N3CCOCC3)cc2c1 Show InChI InChI=1S/C23H22N6O2/c1-28-15-20(14-26-28)16-2-3-18-13-25-21(11-19(18)10-16)27-23(30)17-4-5-24-22(12-17)29-6-8-31-9-7-29/h2-5,10-15H,6-9H2,1H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.23E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293458 (US10106527, Compound 62 | US10544128, Compound 62 ...) Show SMILES CN(C)CCNc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H25N7O/c1-29(2)9-8-25-21-11-17(6-7-24-21)23(31)28-22-12-19-10-16(4-5-18(19)13-26-22)20-14-27-30(3)15-20/h4-7,10-15H,8-9H2,1-3H3,(H,24,25)(H,26,28,31)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.83E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293459 (US10106527, Compound 63 | US10544128, Compound 63 ...) Show SMILES CN(C)CCOc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H24N6O2/c1-28(2)8-9-31-22-12-17(6-7-24-22)23(30)27-21-11-19-10-16(4-5-18(19)13-25-21)20-14-26-29(3)15-20/h4-7,10-15H,8-9H2,1-3H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.70E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293460 (US10106527, Compound 64 | US10544128, Compound 64 ...) Show SMILES CC(C)CN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C27H31N7O/c1-19(2)17-33-8-10-34(11-9-33)26-14-21(6-7-28-26)27(35)31-25-13-23-12-20(4-5-22(23)15-29-25)24-16-30-32(3)18-24/h4-7,12-16,18-19H,8-11,17H2,1-3H3,(H,29,31,35)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.84E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293461 (US10106527, Compound 65 | US10544128, Compound 65 ...) Show SMILES Cn1cc(cn1)-c1ccc2cnc(NC(=O)c3ccnc(OC4CNC4)c3)cc2c1 Show InChI InChI=1S/C22H20N6O2/c1-28-13-18(10-26-28)14-2-3-16-9-25-20(7-17(16)6-14)27-22(29)15-4-5-24-21(8-15)30-19-11-23-12-19/h2-10,13,19,23H,11-12H2,1H3,(H,25,27,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293462 (US10106527, Compound 66 | US11548872, Compound 66 ...) Show SMILES CN1CC(C1)Oc1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H22N6O2/c1-28-13-20(14-28)31-22-9-16(5-6-24-22)23(30)27-21-8-18-7-15(3-4-17(18)10-25-21)19-11-26-29(2)12-19/h3-12,20H,13-14H2,1-2H3,(H,25,27,30)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2.71E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293463 (US10106527, Compound 67 | US10544128, Compound 67 ...) Show SMILES CCN1CCN(CC1)c1cc(ccn1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C25H27N7O/c1-3-31-8-10-32(11-9-31)24-14-19(6-7-26-24)25(33)29-23-13-21-12-18(4-5-20(21)15-27-23)22-16-28-30(2)17-22/h4-7,12-17H,3,8-11H2,1-2H3,(H,27,29,33)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.65E+3	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair
Glycogen synthase kinase-3 beta (Homo sapiens (Human))	BDBM293464 (BDBM427096 | US10106527, Compound 71 | US11548872,...) Show SMILES CN(C)Cc1ccc(cc1)C(=O)Nc1cc2cc(ccc2cn1)-c1cnn(C)c1 Show InChI InChI=1S/C23H23N5O/c1-27(2)14-16-4-6-17(7-5-16)23(29)26-22-11-20-10-18(8-9-19(20)12-24-22)21-13-25-28(3)15-21/h4-13,15H,14H2,1-3H3,(H,24,26,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	728	n/a	n/a	n/a	n/a
Tanabe Research Laboratories USA					Assay Description The GSK3β kinase assay is run using the Ser/Thr 09 peptide Z-lyte assay kit according to manufacturer's instructions (Life Technologiesa Div...				Bioorg Med Chem Lett 17: 4442-6 (2007) BindingDB Entry DOI: 10.7270/Q2862JRD
					More data for this Ligand-Target Pair

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