Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155261 (US9006244, E4a | US9814715, Example 4, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155257 (US9006244, E2a | US9814715, Example 2, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155259 (US9006244, E3a | US9814715, Example 3, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 27 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155261 (US9006244, E4a | US9814715, Example 4, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 43 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM354727 (1-isopropyl-7-(methylsulfonyl)-2-(4-(trifluorometh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 256 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155257 (US9006244, E2a | US9814715, Example 2, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 318 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155259 (US9006244, E3a | US9814715, Example 3, isomer 1) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 398 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155262 (US9006244, E4b | US9814715, Example 4, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 846 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155260 (US9006244, E3b | US9814715, Example 3, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | 1.75E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM354727 (1-isopropyl-7-(methylsulfonyl)-2-(4-(trifluorometh...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.77E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-beta (Homo sapiens (Human)) | BDBM155258 (US9006244, E2b | US9814715, Example 2, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >2.50E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155260 (US9006244, E3b | US9814715, Example 3, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155258 (US9006244, E2b | US9814715, Example 2, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Oxysterols receptor LXR-alpha (Homo sapiens (Human)) | BDBM155262 (US9006244, E4b | US9814715, Example 4, isomer 2) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | >3.33E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Vitae Pharamceuticals, Inc. US Patent | Assay Description Compounds of the invention were assessed in a competition binding assay where different concentrations of compounds were incubated with the LXR ligan... | US Patent US9814715 (2017) BindingDB Entry DOI: 10.7270/Q23R0W1B | |||||||||||
More data for this Ligand-Target Pair |