Compile Data Set for Download or QSAR

Found 75 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 2515   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369720 (US10233160, Compound 10 | US9981925, Compound 10) Show SMILES COc1cc(ccc1Cl)[C@@H](CN1CCC1)Nc1nnnc2c(cccc12)C(N)=O |r| Show InChI InChI=1S/C20H21ClN6O2/c1-29-17-10-12(6-7-15(17)21)16(11-27-8-3-9-27)23-20-14-5-2-4-13(19(22)28)18(14)24-26-25-20/h2,4-7,10,16H,3,8-9,11H2,1H3,(H2,22,28)(H,23,24,25)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369739 (US10233160, Compound 30 | US9981925, Compound 30) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(Br)c1 |r| Show InChI InChI=1S/C18H18BrFN6O/c1-2-22-8-14(10-3-4-13(20)12(19)7-10)26-18-16-15(24-9-25-18)11(17(21)27)5-6-23-16/h3-7,9,14,22H,2,8H2,1H3,(H2,21,27)(H,24,25,26)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369723 (US10233160, Compound 13 | US9981925, Compound 13) Show SMILES CN(C)C[C@@H](Nc1nnnc2c(cccc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18ClF3N6O/c1-29(2)9-15(10-6-7-14(20)13(8-10)19(21,22)23)25-18-12-5-3-4-11(17(24)30)16(12)26-28-27-18/h3-8,15H,9H2,1-2H3,(H2,24,30)(H,25,26,27)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369750 (US10233160, Compound 41 | US9981925, Compound 71) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H18ClF3N6O/c21-14-3-2-11(8-13(14)20(22,23)24)15(9-30-6-1-7-30)29-19-17-16(27-10-28-19)12(18(25)31)4-5-26-17/h2-5,8,10,15H,1,6-7,9H2,(H2,25,31)(H,27,28,29)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369751 (US10233160, Compound 42 | US9981925, Compound 42) Show SMILES CNC[C@@H](Nc1ncnc2c(nccc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16ClF3N6O/c1-24-7-13(9-2-3-12(19)11(6-9)18(20,21)22)28-17-10-4-5-25-15(16(23)29)14(10)26-8-27-17/h2-6,8,13,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369752 (US10233160, Compound 43) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(c(c1)C(F)(F)F)C(F)(F)F |r| Show InChI InChI=1S/C19H16F6N6O/c1-27-7-13(9-2-3-11(18(20,21)22)12(6-9)19(23,24)25)31-17-15-14(29-8-30-17)10(16(26)32)4-5-28-15/h2-6,8,13,27H,7H2,1H3,(H2,26,32)(H,29,30,31)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369753 (US10233160, Compound 44 | US9981925, Compound 44) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(C)c1 |r| Show InChI InChI=1S/C18H19ClN6O/c1-10-7-11(3-4-13(10)19)14(8-21-2)25-18-16-15(23-9-24-18)12(17(20)26)5-6-22-16/h3-7,9,14,21H,8H2,1-2H3,(H2,20,26)(H,23,24,25)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369754 (US10233160, Compound 45 | US9981925, Compound 45) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)cc1 |r| Show InChI InChI=1S/C17H17ClN6O/c1-20-8-13(10-2-4-11(18)5-3-10)24-17-15-14(22-9-23-17)12(16(19)25)6-7-21-15/h2-7,9,13,20H,8H2,1H3,(H2,19,25)(H,22,23,24)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369755 (US10233160, Compound 46 | US9981925, Compound 46) Show SMILES Cc1cc(ccc1Cl)[C@@H](CN1CCC1)Nc1ncnc2c(ccnc12)C(N)=O |r| Show InChI InChI=1S/C20H21ClN6O/c1-12-9-13(3-4-15(12)21)16(10-27-7-2-8-27)26-20-18-17(24-11-25-20)14(19(22)28)5-6-23-18/h3-6,9,11,16H,2,7-8,10H2,1H3,(H2,22,28)(H,24,25,26)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369756 (US10233160, Compound 47 | US9981925, Compound 47) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(C#N)c(Cl)c3)ncnc12 |r| Show InChI InChI=1S/C20H18ClN7O/c21-15-8-12(2-3-13(15)9-22)16(10-28-6-1-7-28)27-20-18-17(25-11-26-20)14(19(23)29)4-5-24-18/h2-5,8,11,16H,1,6-7,10H2,(H2,23,29)(H,25,26,27)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369757 (US10233160, Compound 48 | US9981925, Compound 48) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(F)c(c3)C(F)F)ncnc12 |r| Show InChI InChI=1S/C20H19F3N6O/c21-14-3-2-11(8-13(14)18(22)23)15(9-29-6-1-7-29)28-20-17-16(26-10-27-20)12(19(24)30)4-5-25-17/h2-5,8,10,15,18H,1,6-7,9H2,(H2,24,30)(H,26,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369758 (US10233160, Compound 49 | US9981925, Compound 49) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N6O/c1-24-7-13(9-2-3-12(19)11(6-9)18(20,21)22)28-17-15-14(26-8-27-17)10(16(23)29)4-5-25-15/h2-6,8,13,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369759 (US10233160, Compound 50 | US9981925, Compound 50) Show SMILES CN(C)C[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18F4N6O/c1-29(2)8-14(10-3-4-13(20)12(7-10)19(21,22)23)28-18-16-15(26-9-27-18)11(17(24)30)5-6-25-16/h3-7,9,14H,8H2,1-2H3,(H2,24,30)(H,26,27,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369760 (US10233160, Compound 51 | US9981925, Compound 51) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(c1)C(F)F |r| Show InChI InChI=1S/C18H17F3N6O/c1-23-7-13(9-2-3-12(19)11(6-9)16(20)21)27-18-15-14(25-8-26-18)10(17(22)28)4-5-24-15/h2-6,8,13,16,23H,7H2,1H3,(H2,22,28)(H,25,26,27)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369762 (US10233160, Compound 53 | US9981925, Compound 53) Show SMILES CN(C)C[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(F)c1 |r| Show InChI InChI=1S/C18H18ClFN6O/c1-26(2)8-14(10-3-4-12(19)13(20)7-10)25-18-16-15(23-9-24-18)11(17(21)27)5-6-22-16/h3-7,9,14H,8H2,1-2H3,(H2,21,27)(H,23,24,25)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369775 (US10233160, Compound 66 | US9981925, Compound 66) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1cccc(F)c1 |r| Show InChI InChI=1S/C17H17FN6O/c1-20-8-13(10-3-2-4-11(18)7-10)24-17-15-14(22-9-23-17)12(16(19)25)5-6-21-15/h2-7,9,13,20H,8H2,1H3,(H2,19,25)(H,22,23,24)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369776 (US10233160, Compound 67 | US9981925, Compound 67) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(C)c1 |r| Show InChI InChI=1S/C18H19FN6O/c1-10-7-11(3-4-13(10)19)14(8-21-2)25-18-16-15(23-9-24-18)12(17(20)26)5-6-22-16/h3-7,9,14,21H,8H2,1-2H3,(H2,20,26)(H,23,24,25)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369777 (US10233160, Compound 68 | US9981925, Compound 68) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3cccc(F)c3)ncnc12 |r| Show InChI InChI=1S/C19H19FN6O/c20-13-4-1-3-12(9-13)15(10-26-7-2-8-26)25-19-17-16(23-11-24-19)14(18(21)27)5-6-22-17/h1,3-6,9,11,15H,2,7-8,10H2,(H2,21,27)(H,23,24,25)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369778 (US10233160, Compound 69 | US9981925, Compound 69) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CC(F)C3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H17ClF4N6O/c21-14-2-1-10(5-13(14)20(23,24)25)15(8-31-6-11(22)7-31)30-19-17-16(28-9-29-19)12(18(26)32)3-4-27-17/h1-5,9,11,15H,6-8H2,(H2,26,32)(H,28,29,30)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369779 (US10233160, Compound 70 | US9981925, Compound 70) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CC(O)C3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H18ClF3N6O2/c21-14-2-1-10(5-13(14)20(22,23)24)15(8-30-6-11(31)7-30)29-19-17-16(27-9-28-19)12(18(25)32)3-4-26-17/h1-5,9,11,15,31H,6-8H2,(H2,25,32)(H,27,28,29)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369781 (US10233160, Compound 72 | US9981925, Compound 72) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16ClF3N6O/c1-24-7-13(9-2-3-12(19)11(6-9)18(20,21)22)28-17-15-14(26-8-27-17)10(16(23)29)4-5-25-15/h2-6,8,13,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369782 (US10233160, Compound 73) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(OC(F)(F)F)c(Cl)c3)ncnc12 |r| Show InChI InChI=1S/C20H18ClF3N6O2/c21-13-8-11(2-3-15(13)32-20(22,23)24)14(9-30-6-1-7-30)29-19-17-16(27-10-28-19)12(18(25)31)4-5-26-17/h2-5,8,10,14H,1,6-7,9H2,(H2,25,31)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369783 (US10233160, Compound 74 | US9981925, Compound 74) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(OC(F)(F)F)c(Cl)c1 |r| Show InChI InChI=1S/C18H16ClF3N6O2/c1-24-7-12(9-2-3-13(11(19)6-9)30-18(20,21)22)28-17-15-14(26-8-27-17)10(16(23)29)4-5-25-15/h2-6,8,12,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t12-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369784 (US10233160, Compound 75 | US9981925, Compound 75) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C17H16Cl2N6O/c1-21-7-13(9-2-3-11(18)12(19)6-9)25-17-15-14(23-8-24-17)10(16(20)26)4-5-22-15/h2-6,8,13,21H,7H2,1H3,(H2,20,26)(H,23,24,25)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369785 (US10233160, Compound 76) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(C)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H19F3N6O/c1-10-3-4-11(7-13(10)19(20,21)22)14(8-24-2)28-18-16-15(26-9-27-18)12(17(23)29)5-6-25-16/h3-7,9,14,24H,8H2,1-2H3,(H2,23,29)(H,26,27,28)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369725 (US10233160, Compound 15 | US9981925, Compound 15) Show SMILES CN(C)C[C@@H](Nc1nnnc2c(cccc12)C(N)=O)c1ccc(Cl)c(Cl)c1 |r| Show InChI InChI=1S/C18H18Cl2N6O/c1-26(2)9-15(10-6-7-13(19)14(20)8-10)22-18-12-5-3-4-11(17(21)27)16(12)23-25-24-18/h3-8,15H,9H2,1-2H3,(H2,21,27)(H,22,23,24)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369726 (US10233160, Compound 16 | US9981925, Compound 16) Show SMILES NC(=O)c1cccc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(Cl)c3)nnnc12 |r| Show InChI InChI=1S/C19H18Cl2N6O/c20-14-6-5-11(9-15(14)21)16(10-27-7-2-8-27)23-19-13-4-1-3-12(18(22)28)17(13)24-26-25-19/h1,3-6,9,16H,2,7-8,10H2,(H2,22,28)(H,23,24,25)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369728 (US10233160, Compound 18 | US9981925, Compound 18) Show SMILES NC(=O)c1cccc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C#N)nnnc12 |r| Show InChI InChI=1S/C20H18ClN7O/c21-16-6-5-12(9-13(16)10-22)17(11-28-7-2-8-28)24-20-15-4-1-3-14(19(23)29)18(15)25-27-26-20/h1,3-6,9,17H,2,7-8,11H2,(H2,23,29)(H,24,25,26)/t17-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369730 (US10233160, Compound 20 | US9981925, Compound 20) Show SMILES NC(=O)c1cncc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H18ClF3N6O/c21-15-3-2-11(6-14(15)20(22,23)24)16(9-30-4-1-5-30)29-19-13-8-26-7-12(18(25)31)17(13)27-10-28-19/h2-3,6-8,10,16H,1,4-5,9H2,(H2,25,31)(H,27,28,29)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369731 (US10233160, Compound 21 | US9981925, Compound 21) Show SMILES NC(=O)c1cccc2c(NC3CNCCC3c3cccc(c3)C(F)(F)F)nnnc12 Show InChI InChI=1S/C20H19F3N6O/c21-20(22,23)12-4-1-3-11(9-12)13-7-8-25-10-16(13)26-19-15-6-2-5-14(18(24)30)17(15)27-29-28-19/h1-6,9,13,16,25H,7-8,10H2,(H2,24,30)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369732 (US10233160, Compound 22 | US9981925, Compound 22) Show SMILES NC(=O)c1cccc2c(NC3CNCCC3c3ccc(cc3)C(F)(F)F)nnnc12 Show InChI InChI=1S/C20H19F3N6O/c21-20(22,23)12-6-4-11(5-7-12)13-8-9-25-10-16(13)26-19-15-3-1-2-14(18(24)30)17(15)27-29-28-19/h1-7,13,16,25H,8-10H2,(H2,24,30)(H,26,27,28)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369734 (US10233160, Compound 25 | US9981925, Compound 25) Show SMILES NC(=O)c1ccnc2c(NC3CNCCC3c3ccc(cc3)C(F)(F)F)ncnc12 Show InChI InChI=1S/C20H19F3N6O/c21-20(22,23)12-3-1-11(2-4-12)13-5-7-25-9-15(13)29-19-17-16(27-10-28-19)14(18(24)30)6-8-26-17/h1-4,6,8,10,13,15,25H,5,7,9H2,(H2,24,30)(H,27,28,29)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369735 (US10233160, Compound 26 | US9981925, Compound 26) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(c(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N6O/c1-24-7-13(9-2-3-11(12(19)6-9)18(20,21)22)28-17-15-14(26-8-27-17)10(16(23)29)4-5-25-15/h2-6,8,13,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369736 (US10233160, Compound 27 | US9981925, Compound 27) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(cc3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H19F3N6O/c21-20(22,23)13-4-2-12(3-5-13)15(10-29-8-1-9-29)28-19-17-16(26-11-27-19)14(18(24)30)6-7-25-17/h2-7,11,15H,1,8-10H2,(H2,24,30)(H,26,27,28)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369712 (US10233160, Compound 2 | US9981925, Compound 2) Show SMILES NC(=O)c1cccc2c(NCc3ccc(Cl)c(Cl)c3)nnnc12 Show InChI InChI=1S/C15H11Cl2N5O/c16-11-5-4-8(6-12(11)17)7-19-15-10-3-1-2-9(14(18)23)13(10)20-22-21-15/h1-6H,7H2,(H2,18,23)(H,19,20,21)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369714 (US10233160, Compound 4 | US9981925, Compound 4) Show SMILES NC(=O)c1cccc2c(NCc3ccc(Cl)c(c3)C(F)(F)F)nnnc12 Show InChI InChI=1S/C16H11ClF3N5O/c17-12-5-4-8(6-11(12)16(18,19)20)7-22-15-10-3-1-2-9(14(21)26)13(10)23-25-24-15/h1-6H,7H2,(H2,21,26)(H,22,23,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369724 (US10233160, Compound 14 | US9981925, Compound 14) Show SMILES NC(=O)c1cccc2c(N[C@H](CN3CCC3)c3ccc(Cl)c(c3)C(F)(F)F)nnnc12 |r| Show InChI InChI=1S/C20H18ClF3N6O/c21-15-6-5-11(9-14(15)20(22,23)24)16(10-30-7-2-8-30)26-19-13-4-1-3-12(18(25)31)17(13)27-29-28-19/h1,3-6,9,16H,2,7-8,10H2,(H2,25,31)(H,26,27,28)/t16-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369765 (US10233160, Compound 56 | US9981925, Compound 56) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18F4N6O/c1-2-25-8-14(10-3-4-13(20)12(7-10)19(21,22)23)29-18-16-15(27-9-28-18)11(17(24)30)5-6-26-16/h3-7,9,14,25H,2,8H2,1H3,(H2,24,30)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369766 (US10233160, Compound 57 | US9981925, Compound 57) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C17H16ClFN6O/c1-21-7-13(9-2-3-12(19)11(18)6-9)25-17-15-14(23-8-24-17)10(16(20)26)4-5-22-15/h2-6,8,13,21H,7H2,1H3,(H2,20,26)(H,23,24,25)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369770 (US10233160, Compound 61 | US9981925, Compound 61) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(Cl)c1 |r| Show InChI InChI=1S/C18H18ClFN6O/c1-2-22-8-14(10-3-4-13(20)12(19)7-10)26-18-16-15(24-9-25-18)11(17(21)27)5-6-23-16/h3-7,9,14,22H,2,8H2,1H3,(H2,21,27)(H,24,25,26)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369771 (US10233160, Compound 62 | US9981925, Compound 62) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(F)c(c3)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C20H18F4N6O/c21-14-3-2-11(8-13(14)20(22,23)24)15(9-30-6-1-7-30)29-19-17-16(27-10-28-19)12(18(25)31)4-5-26-17/h2-5,8,10,15H,1,6-7,9H2,(H2,25,31)(H,27,28,29)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369772 (US10233160, Compound 63 | US9981925, Compound 63) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(c(c3)C(F)(F)F)C(F)(F)F)ncnc12 |r| Show InChI InChI=1S/C21H18F6N6O/c22-20(23,24)13-3-2-11(8-14(13)21(25,26)27)15(9-33-6-1-7-33)32-19-17-16(30-10-31-19)12(18(28)34)4-5-29-17/h2-5,8,10,15H,1,6-7,9H2,(H2,28,34)(H,30,31,32)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369773 (US10233160, Compound 64 | US9981925, Compound 64) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1cccc(Cl)c1 |r| Show InChI InChI=1S/C17H17ClN6O/c1-20-8-13(10-3-2-4-11(18)7-10)24-17-15-14(22-9-23-17)12(16(19)25)5-6-21-15/h2-7,9,13,20H,8H2,1H3,(H2,19,25)(H,22,23,24)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369774 (US10233160, Compound 65 | US9981925, Compound 65) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1cccc(Br)c1 |r| Show InChI InChI=1S/C17H17BrN6O/c1-20-8-13(10-3-2-4-11(18)7-10)24-17-15-14(22-9-23-17)12(16(19)25)5-6-21-15/h2-7,9,13,20H,8H2,1H3,(H2,19,25)(H,22,23,24)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369737 (US10233160, Compound 28 | US9981925, Compound 28) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(F)c(Br)c1 |r| Show InChI InChI=1S/C17H16BrFN6O/c1-21-7-13(9-2-3-12(19)11(18)6-9)25-17-15-14(23-8-24-17)10(16(20)26)4-5-22-15/h2-6,8,13,21H,7H2,1H3,(H2,20,26)(H,23,24,25)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369738 (US10233160, Compound 29 | US9981925, Compound 29) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(c(F)c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18F4N6O/c1-2-25-8-14(10-3-4-12(13(20)7-10)19(21,22)23)29-18-16-15(27-9-28-18)11(17(24)30)5-6-26-16/h3-7,9,14,25H,2,8H2,1H3,(H2,24,30)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369741 (US10233160, Compound 32 | US9981925, Compound 32) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1cc(F)c(OC)cc1F |r| Show InChI InChI=1S/C18H18F2N6O2/c1-22-7-13(10-5-12(20)14(28-2)6-11(10)19)26-18-16-15(24-8-25-18)9(17(21)27)3-4-23-16/h3-6,8,13,22H,7H2,1-2H3,(H2,21,27)(H,24,25,26)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369742 (US10233160, Compound 33 | US9981925, Compound 33) Show SMILES CCNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1ccc(Cl)c(c1)C(F)(F)F |r| Show InChI InChI=1S/C19H18ClF3N6O/c1-2-25-8-14(10-3-4-13(20)12(7-10)19(21,22)23)29-18-16-15(27-9-28-18)11(17(24)30)5-6-26-16/h3-7,9,14,25H,2,8H2,1H3,(H2,24,30)(H,27,28,29)/t14-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369744 (US10233160, Compound 35 | US9981925, Compound 35) Show SMILES CNC[C@@H](Nc1ncnc2c(ccnc12)C(N)=O)c1cc(F)cc(c1)C(F)(F)F |r| Show InChI InChI=1S/C18H16F4N6O/c1-24-7-13(9-4-10(18(20,21)22)6-11(19)5-9)28-17-15-14(26-8-27-17)12(16(23)29)2-3-25-15/h2-6,8,13,24H,7H2,1H3,(H2,23,29)(H,26,27,28)/t13-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair
Ribosomal protein S6 kinase beta-1 (Homo sapiens (Human))	BDBM369745 (US10233160, Compound 36 | US9981925, Compound 36) Show SMILES NC(=O)c1ccnc2c(N[C@H](CN3CCC3)c3ccc(Cl)cc3)ncnc12 |r| Show InChI InChI=1S/C19H19ClN6O/c20-13-4-2-12(3-5-13)15(10-26-8-1-9-26)25-19-17-16(23-11-24-19)14(18(21)27)6-7-22-17/h2-7,11,15H,1,8-10H2,(H2,21,27)(H,23,24,25)/t15-/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	<25	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens					Assay Description p70S6K inhibitor compounds were diluted and plated in 96 well plates. A reaction mixture including the following components were then added to the co...				J Med Chem 51: 2216-2226 (2008) BindingDB Entry DOI: 10.7270/Q27H1MWF
					More data for this Ligand-Target Pair

Displayed 1 to 50 (of 75 total )  |  Next  |  Last  >>

Jump to: