Compile Data Set for Download or QSAR

Found 36 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 294   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262997 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-isopropylpipe...) Show SMILES CC(C)C1CCCNC1C(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C21H25N3O2/c1-13(2)16-4-3-8-23-20(16)21(25)24-15-5-6-18-17-7-9-22-11-14(17)12-26-19(18)10-15/h5-7,9-11,13,16,20,23H,3-4,8,12H2,1-2H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262991 ((S)-2-amino-4-methyl-N¿((S)-5-methyl-5H-chromeno[3...) Show SMILES CC(C)C[C@H](N)C(=O)Nc1ccc-2c(O[C@H](C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C19H23N3O2/c1-11(2)8-17(20)19(23)22-13-4-5-15-14-6-7-21-10-16(14)12(3)24-18(15)9-13/h4-7,9-12,17H,8,20H2,1-3H3,(H,22,23)/t12-,17+/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262988 ((R)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-4-m...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1 |r| Show InChI InChI=1S/C18H21N3O2/c1-11(2)7-16(19)18(22)21-13-3-4-15-14-5-6-20-9-12(14)10-23-17(15)8-13/h3-6,8-9,11,16H,7,10,19H2,1-2H3,(H,21,22)/t16-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262989 ((S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-4-m...) Show SMILES CC(C)C[C@H](N)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1 |r| Show InChI InChI=1S/C18H21N3O2/c1-11(2)7-16(19)18(22)21-13-3-4-15-14-5-6-20-9-12(14)10-23-17(15)8-13/h3-6,8-9,11,16H,7,10,19H2,1-2H3,(H,21,22)/t16-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262992 ((2R)-2-amino-4-methyl-N-(5-methyl-5H-chromeno[3,4-...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc-2c(OC(C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C19H23N3O2/c1-11(2)8-17(20)19(23)22-13-4-5-15-14-6-7-21-10-16(14)12(3)24-18(15)9-13/h4-7,9-12,17H,8,20H2,1-3H3,(H,22,23)/t12?,17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262993 ( (R)-2-amino-4-methyl-N—((R)-5-methyl-5H-chro...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc-2c(O[C@@H](C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C19H23N3O2/c1-11(2)8-17(20)19(23)22-13-4-5-15-14-6-7-21-10-16(14)12(3)24-18(15)9-13/h4-7,9-12,17H,8,20H2,1-3H3,(H,22,23)/t12-,17+/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263022 ((S)-2-amino-N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-p...) Show SMILES N[C@H](C(=O)Nc1ccc-2c(OCc3cnccc-23)c1)c1ccccc1 |r| Show InChI InChI=1S/C20H17N3O2/c21-19(13-4-2-1-3-5-13)20(24)23-15-6-7-17-16-8-9-22-11-14(16)12-25-18(17)10-15/h1-11,19H,12,21H2,(H,23,24)/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.90	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262990 ( (S)-2-amino-4-methyl-N¿((R)-5-methyl-5H-chromeno[...) Show SMILES CC(C)C[C@H](N)C(=O)Nc1ccc-2c(O[C@@H](C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C19H23N3O2/c1-11(2)8-17(20)19(23)22-13-4-5-15-14-6-7-21-10-16(14)12(3)24-18(15)9-13/h4-7,9-12,17H,8,20H2,1-3H3,(H,22,23)/t12-,17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	11	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263001 (N-(5H-chromeno[3,4-c]pyridin-8-yl)pentanamide | US...) Show SMILES CCCCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C17H18N2O2/c1-2-3-4-17(20)19-13-5-6-15-14-7-8-18-10-12(14)11-21-16(15)9-13/h5-10H,2-4,11H2,1H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262995 ((R)-2-amino-N-(5,5-dimethyl-5H-chromeno[3,4-c]pyri...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc-2c(OC(C)(C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C20H25N3O2/c1-12(2)9-17(21)19(24)23-13-5-6-15-14-7-8-22-11-16(14)20(3,4)25-18(15)10-13/h5-8,10-12,17H,9,21H2,1-4H3,(H,23,24)/t17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262994 ((R)-2-amino-4-methyl-N—((S)-5-methyl-5H-chrom...) Show SMILES CC(C)C[C@@H](N)C(=O)Nc1ccc-2c(O[C@H](C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C19H23N3O2/c1-11(2)8-17(20)19(23)22-13-4-5-15-14-6-7-21-10-16(14)12(3)24-18(15)9-13/h4-7,9-12,17H,8,20H2,1-3H3,(H,22,23)/t12-,17-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263023 ((S)—N1-(5H-chromeno[3,4-c]pyridin-8-yl)-2-phe...) Show SMILES N[C@H](CNc1ccc-2c(OCc3cnccc-23)c1)c1ccccc1 |r| Show InChI InChI=1S/C20H19N3O/c21-19(14-4-2-1-3-5-14)12-23-16-6-7-18-17-8-9-22-11-15(17)13-24-20(18)10-16/h1-11,19,23H,12-13,21H2/t19-/m1/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263021 ((S)—N-(2-acetamido-5H-chromeno[3,4-c]pyridin-...) Show SMILES CC(C)C[C@H](N)C(=O)Nc1ccc-2c(OCc3cnc(NC(C)=O)cc-23)c1 |r| Show InChI InChI=1S/C20H24N4O3/c1-11(2)6-17(21)20(26)24-14-4-5-15-16-8-19(23-12(3)25)22-9-13(16)10-27-18(15)7-14/h4-5,7-9,11,17H,6,10,21H2,1-3H3,(H,24,26)(H,22,23,25)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263020 (N-(9-bromo-5H-chromeno[3,4-c]pyridin-8-yl)pentanam...) Show SMILES CCCCC(=O)Nc1cc2OCc3cnccc3-c2cc1Br Show InChI InChI=1S/C17H17BrN2O2/c1-2-3-4-17(21)20-15-8-16-13(7-14(15)18)12-5-6-19-9-11(12)10-22-16/h5-9H,2-4,10H2,1H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263017 (N-(5H-chromeno[3,4-c]pyridin-8-yl)butyramide | US9...) Show SMILES CCCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H16N2O2/c1-2-3-16(19)18-12-4-5-14-13-6-7-17-9-11(13)10-20-15(14)8-12/h4-9H,2-3,10H2,1H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263016 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-4-methylpentana...) Show SMILES CC(C)CCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C18H20N2O2/c1-12(2)3-6-18(21)20-14-4-5-16-15-7-8-19-10-13(15)11-22-17(16)9-14/h4-5,7-10,12H,3,6,11H2,1-2H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263013 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-methylbutanam...) Show SMILES CC(C)CC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C17H18N2O2/c1-11(2)7-17(20)19-13-3-4-15-14-5-6-18-9-12(14)10-21-16(15)8-13/h3-6,8-9,11H,7,10H2,1-2H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263012 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3,3-dimethylbut...) Show SMILES CC(C)(C)CC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C18H20N2O2/c1-18(2,3)9-17(21)20-13-4-5-15-14-6-7-19-10-12(14)11-22-16(15)8-13/h4-8,10H,9,11H2,1-3H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263000 (N-(5H-chromeno[3,4-c]pyridin-8-yl)pent-4-ynamide |...) Show SMILES O=C(CCC#C)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C17H14N2O2/c1-2-3-4-17(20)19-13-5-6-15-14-7-8-18-10-12(14)11-21-16(15)9-13/h1,5-10H,3-4,11H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	55	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262996 ((S)-2-amino-N-(5,5-dimethyl-5H-chromeno[3,4-c]pyri...) Show SMILES CC(C)C[C@H](N)C(=O)Nc1ccc-2c(OC(C)(C)c3cnccc-23)c1 |r| Show InChI InChI=1S/C20H25N3O2/c1-12(2)9-17(21)19(24)23-13-5-6-15-14-7-8-22-11-16(14)20(3,4)25-18(15)10-13/h5-8,10-12,17H,9,21H2,1-4H3,(H,23,24)/t17-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	129	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263010 (N-(5H-chromeno[3,4-c]pyridin-8-yl)isobutyramide | ...) Show SMILES CC(C)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H16N2O2/c1-10(2)16(19)18-12-3-4-14-13-5-6-17-8-11(13)9-20-15(14)7-12/h3-8,10H,9H2,1-2H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263011 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-cyanoacetamid...) Show SMILES O=C(CC#N)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C15H11N3O2/c16-5-3-15(19)18-11-1-2-13-12-4-6-17-8-10(12)9-20-14(13)7-11/h1-2,4,6-8H,3,9H2,(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263018 (N-(5H-chromeno[3,4-c]pyridin-8-yl)pivalamide | US9...) Show SMILES CC(C)(C)C(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C17H18N2O2/c1-17(2,3)16(20)19-12-4-5-14-13-6-7-18-9-11(13)10-21-15(14)8-12/h4-9H,10H2,1-3H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263019 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-2-(dimethylamin...) Show SMILES CN(C)CC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H17N3O2/c1-19(2)9-16(20)18-12-3-4-14-13-5-6-17-8-11(13)10-21-15(14)7-12/h3-8H,9-10H2,1-2H3,(H,18,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263015 (US9708337, 29 | methyl 4-((5H-chromeno[3,4-c]pyrid...) Show SMILES COC(=O)CCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C17H16N2O4/c1-22-17(21)5-4-16(20)19-12-2-3-14-13-6-7-18-9-11(13)10-23-15(14)8-12/h2-3,6-9H,4-5,10H2,1H3,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262999 (1-(5H-chromeno[3,4-c]pyridin-8-yl)-3-cyclohexylure...) Show SMILES O=C(NC1CCCCC1)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C19H21N3O2/c23-19(21-14-4-2-1-3-5-14)22-15-6-7-17-16-8-9-20-11-13(16)12-24-18(17)10-15/h6-11,14H,1-5,12H2,(H2,21,22,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263009 (N-(5H-chromeno[3,4-c]pyridin-8-yl)cyclohexanecarbo...) Show SMILES O=C(Nc1ccc-2c(OCc3cnccc-23)c1)C1CCCCC1 Show InChI InChI=1S/C19H20N2O2/c22-19(13-4-2-1-3-5-13)21-15-6-7-17-16-8-9-20-11-14(16)12-23-18(17)10-15/h6-11,13H,1-5,12H2,(H,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263007 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-4-sulfamoylbuta...) Show SMILES NS(=O)(=O)CCCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H17N3O4S/c17-24(21,22)7-1-2-16(20)19-12-3-4-14-13-5-6-18-9-11(13)10-23-15(14)8-12/h3-6,8-9H,1-2,7,10H2,(H,19,20)(H2,17,21,22)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263006 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-1-cyanocyclopro...) Show SMILES O=C(Nc1ccc-2c(OCc3cnccc-23)c1)C1(CC1)C#N Show InChI InChI=1S/C17H13N3O2/c18-10-17(4-5-17)16(21)20-12-1-2-14-13-3-6-19-8-11(13)9-22-15(14)7-12/h1-3,6-8H,4-5,9H2,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263005 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-hydroxypropan...) Show SMILES OCCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C15H14N2O3/c18-6-4-15(19)17-11-1-2-13-12-3-5-16-8-10(12)9-20-14(13)7-11/h1-3,5,7-8,18H,4,6,9H2,(H,17,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263004 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-methoxypropan...) Show SMILES COCCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H16N2O3/c1-20-7-5-16(19)18-12-2-3-14-13-4-6-17-9-11(13)10-21-15(14)8-12/h2-4,6,8-9H,5,7,10H2,1H3,(H,18,19)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263003 (N-(5H-chromeno[3,4-c]pyridin-8-yl)acetamide | US97...) Show SMILES CC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C14H12N2O2/c1-9(17)16-11-2-3-13-12-4-5-15-7-10(12)8-18-14(13)6-11/h2-7H,8H2,1H3,(H,16,17)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263002 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-cyanopropanam...) Show SMILES O=C(CCC#N)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C16H13N3O2/c17-6-1-2-16(20)19-12-3-4-14-13-5-7-18-9-11(13)10-21-15(14)8-12/h3-5,7-9H,1-2,10H2,(H,19,20)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM262998 (US9708337, 12 | neopentyl 5H-chromeno[3,4-c]pyridi...) Show SMILES CC(C)(C)COC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C18H20N2O3/c1-18(2,3)11-23-17(21)20-13-4-5-15-14-6-7-19-9-12(14)10-22-16(15)8-13/h4-9H,10-11H2,1-3H3,(H,20,21)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263014 (N-(5H-chromeno[3,4-c]pyridin-8-yl)propionamide | U...) Show SMILES CCC(=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C15H14N2O2/c1-2-15(18)17-11-3-4-13-12-5-6-16-8-10(12)9-19-14(13)7-11/h3-8H,2,9H2,1H3,(H,17,18)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	652	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM263008 (N-(5H-chromeno[3,4-c]pyridin-8-yl)-3-(2-oxopyrroli...) Show SMILES O=C(CCN1CCCC1=O)Nc1ccc-2c(OCc3cnccc-23)c1 Show InChI InChI=1S/C19H19N3O3/c23-18(6-9-22-8-1-2-19(22)24)21-14-3-4-16-15-5-7-20-11-13(15)12-25-17(16)10-14/h3-5,7,10-11H,1-2,6,8-9,12H2,(H,21,23)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	7.4	25
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US9708337 (2017) BindingDB Entry DOI: 10.7270/Q29W0HH9
					More data for this Ligand-Target Pair