Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50000310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A (Homo sapiens (Human))	BDBM50335099 (4-chlorobenzo[d]thiazol-2-amine | CHEMBL1413383 | ...) Show SMILES Nc1nc2c(Cl)cccc2s1 Show InChI InChI=1S/C7H5ClN2S/c8-4-2-1-3-5-6(4)10-7(9)11-5/h1-3H,(H2,9,10)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents	PDB Article PubMed	2.10E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
IOTA Pharmaceuticals Curated by ChEMBL					Assay Description Inhibition of N-terminal 6xHis-tagged PDE10A (unknown origin) expressed in BL21 (DE3) RIL cells using 3',5'-cGMP as substrate by microcalorimetric as...				J Med Chem 61: 1415-1424 (2018) Article DOI: 10.1021/acs.jmedchem.7b00404 BindingDB Entry DOI: 10.7270/Q2GX4DZ9
					More data for this Ligand-Target Pair				3D Structure (crystal)