Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50008290   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50513919 (CHEMBL4457162) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3cccnc23)cc1 Show InChI InChI=1S/C19H15N3O2S/c23-19(21-24)14-9-7-13(8-10-14)12-22-15-4-1-2-5-16(15)25-17-6-3-11-20-18(17)22/h1-11,24H,12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM22449 (CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...) Show SMILES OCc1ccc(cc1)[C@@H]1C[C@H](CSc2nc(c(o2)-c2ccccc2)-c2ccccc2)O[C@@H](O1)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1 |r| Show InChI InChI=1S/C41H43N3O7S/c45-26-28-17-19-29(20-18-28)35-25-34(27-52-41-43-38(30-11-5-3-6-12-30)39(51-41)31-13-7-4-8-14-31)49-40(50-35)32-21-23-33(24-22-32)42-36(46)15-9-1-2-10-16-37(47)44-48/h3-8,11-14,17-24,34-35,40,45,48H,1-2,9-10,15-16,25-27H2,(H,42,46)(H,44,47)/t34-,35+,40+/m1/s1	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517576 (CHEMBL4468273) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccncc23)cc1 Show InChI InChI=1S/C19H15N3O2S/c23-19(21-24)14-7-5-13(6-8-14)12-22-15-3-1-2-4-17(15)25-18-9-10-20-11-16(18)22/h1-11,24H,12H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517583 (CHEMBL4556275) Show SMILES ONC(=O)c1ccc(CN2c3ccncc3Sc3ccncc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-18(21-24)13-3-1-12(2-4-13)11-22-14-5-7-20-10-17(14)25-16-6-8-19-9-15(16)22/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	9	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517567 (CHEMBL4545246) Show SMILES COc1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1 Show InChI InChI=1S/C21H18N2O3S/c1-26-16-10-11-20-18(12-16)23(17-4-2-3-5-19(17)27-20)13-14-6-8-15(9-7-14)21(24)22-25/h2-12,25H,13H2,1H3,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517585 (CHEMBL4443794) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccnnc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-18(21-24)13-7-5-12(6-8-13)11-22-14-3-1-2-4-15(14)25-16-9-10-19-20-17(16)22/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	11	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517570 (CHEMBL4530950) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(Cl)cc23)cc1 Show InChI InChI=1S/C20H15ClN2O2S/c21-15-9-10-19-17(11-15)23(16-3-1-2-4-18(16)26-19)12-13-5-7-14(8-6-13)20(24)22-25/h1-11,25H,12H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517572 (CHEMBL4439108) Show SMILES ONC(=O)c1ccc(CN2c3ccncc3Sc3ncccc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-17(21-24)13-5-3-12(4-6-13)11-22-14-7-9-19-10-16(14)25-18-15(22)2-1-8-20-18/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	12	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517574 (CHEMBL4444811) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3S(=O)(=O)c3ccccc23)cc1 Show InChI InChI=1S/C20H16N2O4S/c23-20(21-24)15-11-9-14(10-12-15)13-22-16-5-1-3-7-18(16)27(25,26)19-8-4-2-6-17(19)22/h1-12,24H,13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	13	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517578 (CHEMBL4546254) Show SMILES ONC(=O)c1ccc(CN2c3cccnc3Sc3cccnc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-17(21-24)13-7-5-12(6-8-13)11-22-14-3-1-10-20-18(14)25-15-4-2-9-19-16(15)22/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	14	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517569 (CHEMBL4450965) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3cccc(Cl)c23)cc1 Show InChI InChI=1S/C20H15ClN2O2S/c21-15-4-3-7-18-19(15)23(16-5-1-2-6-17(16)26-18)12-13-8-10-14(11-9-13)20(24)22-25/h1-11,25H,12H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	16	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517577 (CHEMBL4442266) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3nccnc23)cc1 Show InChI InChI=1S/C18H14N4O2S/c23-17(21-24)13-7-5-12(6-8-13)11-22-14-3-1-2-4-15(14)25-18-16(22)19-9-10-20-18/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517581 (CHEMBL4581606) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3cc(Cl)nnc23)cc1 Show InChI InChI=1S/C18H13ClN4O2S/c19-16-9-15-17(21-20-16)23(13-3-1-2-4-14(13)26-15)10-11-5-7-12(8-6-11)18(24)22-25/h1-9,25H,10H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	18	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517566 (CHEMBL4436946) Show SMILES ONC(=O)c1ccc(CN2N=CC=C3Sc4ccccc4N=C23)cc1 |c:10,t:12,22| Show InChI InChI=1S/C18H14N4O2S/c23-18(21-24)13-7-5-12(6-8-13)11-22-17-16(9-10-19-22)25-15-4-2-1-3-14(15)20-17/h1-10,24H,11H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517568 (CHEMBL4438566) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccccc23)cc1 Show InChI InChI=1S/C20H16N2O2S/c23-20(21-24)15-11-9-14(10-12-15)13-22-16-5-1-3-7-18(16)25-19-8-4-2-6-17(19)22/h1-12,24H,13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517565 (CHEMBL4472834) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3Sc3ccc(cc23)C(F)(F)F)cc1 Show InChI InChI=1S/C21H15F3N2O2S/c22-21(23,24)15-9-10-19-17(11-15)26(16-3-1-2-4-18(16)29-19)12-13-5-7-14(8-6-13)20(27)25-28/h1-11,28H,12H2,(H,25,27)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50380399 (CHEMBL2018302 | Tubastatin A | US10227295, Compoun...) Show SMILES CN1CCc2c(C1)c1ccccc1n2Cc1ccc(cc1)C(=O)NO Show InChI InChI=1S/C20H21N3O2/c1-22-11-10-19-17(13-22)16-4-2-3-5-18(16)23(19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517571 (CHEMBL4551531) Show SMILES CCSc1ccc2Sc3ccccc3N(Cc3ccc(cc3)C(=O)NO)c2c1 Show InChI InChI=1S/C22H20N2O2S2/c1-2-27-17-11-12-21-19(13-17)24(18-5-3-4-6-20(18)28-21)14-15-7-9-16(10-8-15)22(25)23-26/h3-13,26H,2,14H2,1H3,(H,23,25)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517573 (CHEMBL4436806) Show SMILES CN1CCC2=C(C1)N(Cc1ccc(cc1)C(=O)NO)c1ccccc1S2 |c:4| Show InChI InChI=1S/C20H21N3O2S/c1-22-11-10-19-17(13-22)23(16-4-2-3-5-18(16)26-19)12-14-6-8-15(9-7-14)20(24)21-25/h2-9,25H,10-13H2,1H3,(H,21,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517579 (CHEMBL4442157) Show SMILES Cc1nc2N(Cc3ccc(cc3)C(=O)NO)c3ccccc3Sc2s1 Show InChI InChI=1S/C18H15N3O2S2/c1-11-19-16-18(24-11)25-15-5-3-2-4-14(15)21(16)10-12-6-8-13(9-7-12)17(22)20-23/h2-9,23H,10H2,1H3,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517575 (CHEMBL4473451) Show SMILES ONC(=O)c1ccc(CN2c3ccccc3[S+]([O-])c3ccccc23)cc1 Show InChI InChI=1S/C20H16N2O3S/c23-20(21-24)15-11-9-14(10-12-15)13-22-16-5-1-3-7-18(16)26(25)19-8-4-2-6-17(19)22/h1-12,24H,13H2,(H,21,23)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	77	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM19149 (CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...) Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1 Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank Article PubMed	n/a	n/a	104	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517584 (CHEMBL4447453) Show SMILES ONC(=O)c1ccc(CN2N=C(Cl)C=C3Sc4ccccc4N=C23)cc1 |t:10,13,23| Show InChI InChI=1S/C18H13ClN4O2S/c19-16-9-15-17(20-13-3-1-2-4-14(13)26-15)23(21-16)10-11-5-7-12(8-6-11)18(24)22-25/h1-9,25H,10H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517582 (CHEMBL4534310) Show SMILES ONC(=O)c1ccc(CCN2c3ccccc3Sc3ccccc23)cc1 Show InChI InChI=1S/C21H18N2O2S/c24-21(22-25)16-11-9-15(10-12-16)13-14-23-17-5-1-3-7-19(17)26-20-8-4-2-6-18(20)23/h1-12,25H,13-14H2,(H,22,24)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	136	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair
Histone deacetylase 6 (Homo sapiens (Human))	BDBM50517580 (CHEMBL4442134) Show SMILES ONC(=O)c1ccc(cc1)N1c2ccccc2Sc2ccccc12 Show InChI InChI=1S/C19H14N2O2S/c22-19(20-23)13-9-11-14(12-10-13)21-15-5-1-3-7-17(15)24-18-8-4-2-6-16(18)21/h1-12,23H,(H,20,22)	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.67E+3	n/a	n/a	n/a	n/a	n/a	n/a
Ludwig-Maximilians University Munich Curated by ChEMBL					Assay Description Inhibition of recombinant N-terminal GST-tagged human HDAC6 expressed in baculovirus expression system using fluorogenic ZMAL as substrate incubated ...				J Med Chem 62: 1138-1166 (2019) Article DOI: 10.1021/acs.jmedchem.8b01090 BindingDB Entry DOI: 10.7270/Q2J67MB7
					More data for this Ligand-Target Pair