Compile Data Set for Download or QSAR

Found 25 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50037935   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Glucocorticoid receptor (Homo sapiens (Human))	BDBM18627 ((10S,11S,14S,15S,17R)-17-[4-(dimethylamino)phenyl]...) Show SMILES [H][C@@]12CC[C@@](O)(C#CC)[C@@]1(C)C[C@@H](C1=C3CCC(=O)C=C3CC[C@@]21[H])c1ccc(cc1)N(C)C |r,c:14,20| Show InChI InChI=1S/C29H35NO2/c1-5-15-29(32)16-14-26-24-12-8-20-17-22(31)11-13-23(20)27(24)25(18-28(26,29)2)19-6-9-21(10-7-19)30(3)4/h6-7,9-10,17,24-26,32H,8,11-14,16,18H2,1-4H3/t24-,25+,26-,28-,29-/m0/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair				3D Structure (crystal)
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206107 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(C)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-5-7-23(8-6-22)15-17-34(37)18-16-30-32-31(28-14-13-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-9-11-26(12-10-24)35(3)4/h5-12,19,29-30,32,37H,13-14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	22.1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206109 ((8S,11R,13S,14R,17S)-17-(4-bromo-phenylethynyl)-11...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(Br)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34BrNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	31.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206097 ((8S,11R,13S,14R,17S)-17-(3,5-difluoro-phenylethyny...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cc(F)cc(F)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C33H33F2NO3/c1-32-18-28(21-4-6-25(7-5-21)36(2)3)30-27-9-8-26(37)16-22(27)19-39-31(30)29(32)11-13-33(32,38)12-10-20-14-23(34)17-24(35)15-20/h4-7,14-17,28-29,31,38H,8-9,11,13,18-19H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	34.4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206111 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(C)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-6-5-7-23(18-22)14-16-34(37)17-15-30-32-31(28-13-12-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-8-10-26(11-9-24)35(3)4/h5-11,18-19,29-30,32,37H,12-13,15,17,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	36.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206106 ((8S,11R,13S,14R)-11-(4-dimethylamino-phenyl)-17-(4...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(F)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |r,t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	37.6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206113 (4-[(8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(cc2)C#N)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:34,41| Show InChI InChI=1S/C34H34N2O3/c1-33-19-29(24-8-10-26(11-9-24)36(2)3)31-28-13-12-27(37)18-25(28)21-39-32(31)30(33)15-17-34(33,38)16-14-22-4-6-23(20-35)7-5-22/h4-11,18,29-30,32,38H,12-13,15,17,19,21H2,1-3H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	41.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206114 ((8S,11R,13S,14R,17S)-17-(4-chloro-phenylethynyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(Cl)cc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34ClNO3/c1-32-19-28(22-6-10-25(11-7-22)35(2)3)30-27-13-12-26(36)18-23(27)20-38-31(30)29(32)15-17-33(32,37)16-14-21-4-8-24(34)9-5-21/h4-11,18,28-29,31,37H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	43.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206102 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(c2)C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-28(22-7-9-25(10-8-22)38(2)3)30-27-12-11-26(39)18-23(27)20-41-31(30)29(32)14-16-33(32,40)15-13-21-5-4-6-24(17-21)34(35,36)37/h4-10,17-18,28-29,31,40H,11-12,14,16,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	45.4	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206112 ((8S,11R,13S,14R,17S)-17-(3-chloro-phenylethynyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(Cl)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34ClNO3/c1-32-19-28(22-7-9-25(10-8-22)35(2)3)30-27-12-11-26(36)18-23(27)20-38-31(30)29(32)14-16-33(32,37)15-13-21-5-4-6-24(34)17-21/h4-10,17-18,28-29,31,37H,11-12,14,16,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	48.9	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206104 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-27(21-8-10-24(11-9-21)38(2)3)30-26-13-12-25(39)18-23(26)20-41-31(30)29(32)15-17-33(32,40)16-14-22-6-4-5-7-28(22)34(35,36)37/h4-11,18,27,29,31,40H,12-13,15,17,19-20H2,1-3H3/t27-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	51	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206115 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccsc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:31,38| Show InChI InChI=1S/C31H33NO3S/c1-30-17-26(21-4-6-23(7-5-21)32(2)3)28-25-9-8-24(33)16-22(25)18-35-29(28)27(30)11-14-31(30,34)13-10-20-12-15-36-19-20/h4-7,12,15-16,19,26-27,29,34H,8-9,11,14,17-18H2,1-3H3/t26-,27+,29+,30+,31+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206101 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccc(F)c2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-28(22-7-9-25(10-8-22)35(2)3)30-27-12-11-26(36)18-23(27)20-38-31(30)29(32)14-16-33(32,37)15-13-21-5-4-6-24(34)17-21/h4-10,17-18,28-29,31,37H,11-12,14,16,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	56.6	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206103 ((8S,11R,13S,14R,17S)-17-(2-bromo-phenylethynyl)-11...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2Br)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34BrNO3/c1-32-19-27(21-8-10-24(11-9-21)35(2)3)30-26-13-12-25(36)18-23(26)20-38-31(30)28(32)15-17-33(32,37)16-14-22-6-4-5-7-29(22)34/h4-11,18,27-28,31,37H,12-13,15,17,19-20H2,1-3H3/t27-,28+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	62.7	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206098 ((8S,11R,13S,14R,17S)-17-(2-chloro-phenylethynyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2Cl)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34ClNO3/c1-32-19-27(21-8-10-24(11-9-21)35(2)3)30-26-13-12-25(36)18-23(26)20-38-31(30)28(32)15-17-33(32,37)16-14-22-6-4-5-7-29(22)34/h4-11,18,27-28,31,37H,12-13,15,17,19-20H2,1-3H3/t27-,28+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	64.8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206100 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C33H34FNO3/c1-32-19-27(21-8-10-24(11-9-21)35(2)3)30-26-13-12-25(36)18-23(26)20-38-31(30)28(32)15-17-33(32,37)16-14-22-6-4-5-7-29(22)34/h4-11,18,27-28,31,37H,12-13,15,17,19-20H2,1-3H3/t27-,28+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	65.1	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206116 ((8S,11R,13S,14R,17S)-17-(4-tert-butyl-phenylethyny...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(cc2)C(C)(C)C)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C37H43NO3/c1-35(2,3)27-11-7-24(8-12-27)17-19-37(40)20-18-32-34-33(30-16-15-29(39)21-26(30)23-41-34)31(22-36(32,37)4)25-9-13-28(14-10-25)38(5)6/h7-14,21,31-32,34,40H,15-16,18,20,22-23H2,1-6H3/t31-,32+,34+,36+,37+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	65.8	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206117 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES COc1ccc(cc1)C#C[C@]1(O)CC[C@H]2[C@@H]3OCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C |c:26,t:19| Show InChI InChI=1S/C34H37NO4/c1-33-20-29(23-7-9-25(10-8-23)35(2)3)31-28-14-11-26(36)19-24(28)21-39-32(31)30(33)16-18-34(33,37)17-15-22-5-12-27(38-4)13-6-22/h5-10,12-13,19,29-30,32,37H,11,14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	80.3	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50200655 ((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...) Show SMILES CC#C[C@]1(O)CC[C@H]2[C@@H]3OCC4=CC(=O)CCC4=C3[C@H](C[C@]12C)c1ccc(cc1)N(C)C |r,c:18,t:11| Show InChI InChI=1S/C28H33NO3/c1-5-13-28(31)14-12-24-26-25(22-11-10-21(30)15-19(22)17-32-26)23(16-27(24,28)2)18-6-8-20(9-7-18)29(3)4/h6-9,15,23-24,26,31H,10-12,14,16-17H2,1-4H3/t23-,24+,26+,27+,28+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	86.5	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206108 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccc(cc2)C(F)(F)F)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:36,43| Show InChI InChI=1S/C34H34F3NO3/c1-32-19-28(22-6-10-25(11-7-22)38(2)3)30-27-13-12-26(39)18-23(27)20-41-31(30)29(32)15-17-33(32,40)16-14-21-4-8-24(9-5-21)34(35,36)37/h4-11,18,28-29,31,40H,12-13,15,17,19-20H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	111	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206099 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2C)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:33,40| Show InChI InChI=1S/C34H37NO3/c1-22-7-5-6-8-23(22)15-17-34(37)18-16-30-32-31(28-14-13-27(36)19-25(28)21-38-32)29(20-33(30,34)2)24-9-11-26(12-10-24)35(3)4/h5-12,19,29-30,32,37H,13-14,16,18,20-21H2,1-4H3/t29-,30+,32+,33+,34+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	113	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206105 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccn2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:32,39| Show InChI InChI=1S/C32H34N2O3/c1-31-19-27(21-7-9-24(10-8-21)34(2)3)29-26-12-11-25(35)18-22(26)20-37-30(29)28(31)14-16-32(31,36)15-13-23-6-4-5-17-33-23/h4-10,17-18,27-28,30,36H,11-12,14,16,19-20H2,1-3H3/t27-,28+,30+,31+,32+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	175	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206096 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccncc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:32,39| Show InChI InChI=1S/C32H34N2O3/c1-31-19-27(22-4-6-24(7-5-22)34(2)3)29-26-9-8-25(35)18-23(26)20-37-30(29)28(31)11-15-32(31,36)14-10-21-12-16-33-17-13-21/h4-7,12-13,16-18,27-28,30,36H,8-9,11,15,19-20H2,1-3H3/t27-,28+,30+,31+,32+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	247	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50200660 ((8S,11R,13S,14R,17S)-11-(4-Dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2ccccc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |r,t:32,39| Show InChI InChI=1S/C33H35NO3/c1-32-20-28(23-9-11-25(12-10-23)34(2)3)30-27-14-13-26(35)19-24(27)21-37-31(30)29(32)16-18-33(32,36)17-15-22-7-5-4-6-8-22/h4-12,19,28-29,31,36H,13-14,16,18,20-21H2,1-3H3/t28-,29+,31+,32+,33+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	304	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair
Glucocorticoid receptor (Homo sapiens (Human))	BDBM50206110 ((8S,11R,13S,14R,17S)-11-(4-dimethylamino-phenyl)-1...) Show SMILES CN(C)c1ccc(cc1)[C@H]1C[C@@]2(C)[C@@H](CC[C@@]2(O)C#Cc2cccnc2)[C@@H]2OCC3=CC(=O)CCC3=C12 |t:32,39| Show InChI InChI=1S/C32H34N2O3/c1-31-18-27(22-6-8-24(9-7-22)34(2)3)29-26-11-10-25(35)17-23(26)20-37-30(29)28(31)13-15-32(31,36)14-12-21-5-4-16-33-19-21/h4-9,16-17,19,27-28,30,36H,10-11,13,15,18,20H2,1-3H3/t27-,28+,30+,31+,32+/m1/s1	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	342	n/a	n/a	n/a	n/a	n/a	n/a
Johnson and Johnson Pharmaceutical Research and Development Curated by ChEMBL					Assay Description Antagonist activity at human glucocorticoid receptor assessed as inhibition of corticoid-induced transcription in human A549 cells by GRE-linked luci...				Bioorg Med Chem Lett 17: 2531-4 (2007) Article DOI: 10.1016/j.bmcl.2007.02.013 BindingDB Entry DOI: 10.7270/Q2RV0PH2
					More data for this Ligand-Target Pair