Compile Data Set for Download or QSAR

Found 29 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 50041922   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50143697 (8-{2-[4-(2,5-Dichloro-phenyl)-piperazin-1-yl]-ethy...) Show SMILES Clc1ccc(Cl)c(c1)N1CCN(CCN2C(=O)CC3(CCCC3)CC2=O)CC1 Show InChI InChI=1S/C21H27Cl2N3O2/c22-16-3-4-17(23)18(13-16)25-10-7-24(8-11-25)9-12-26-19(27)14-21(15-20(26)28)5-1-2-6-21/h3-4,13H,1-2,5-12,14-15H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	0.129	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50006952 (2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...) Show SMILES COc1ccccc1N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C23H25N5O3/c1-31-19-9-5-4-8-18(19)27-13-10-26(11-14-27)12-15-28-22(29)21-20(25-23(28)30)16-6-2-3-7-17(16)24-21/h2-9,24H,10-15H2,1H3,(H,25,30)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.363	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418765 (CHEMBL1796046) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC(C)(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C27H35N3O3/c1-27(22-10-4-3-5-11-22)20-25(31)30(26(32)21-27)15-9-8-14-28-16-18-29(19-17-28)23-12-6-7-13-24(23)33-2/h3-7,10-13H,8-9,14-21H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	14.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418752 (CHEMBL1796033) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C26H33N3O3/c1-32-24-12-6-5-11-23(24)28-17-15-27(16-18-28)13-7-8-14-29-25(30)19-22(20-26(29)31)21-9-3-2-4-10-21/h2-6,9-12,22H,7-8,13-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	15.8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418769 (CHEMBL1796050) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC3(CCc4ccccc34)CC2=O)CC1 Show InChI InChI=1S/C28H35N3O3/c1-34-25-11-5-4-10-24(25)30-18-16-29(17-19-30)14-6-7-15-31-26(32)20-28(21-27(31)33)13-12-22-8-2-3-9-23(22)28/h2-5,8-11H,6-7,12-21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	16.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418745 (CHEMBL319972) Show SMILES CC(C)(C)c1ccc(cc1)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C26H31N5O2/c1-26(2,3)18-8-10-19(11-9-18)30-15-12-29(13-16-30)14-17-31-24(32)23-22(28-25(31)33)20-6-4-5-7-21(20)27-23/h4-11,27H,12-17H2,1-3H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	19.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418755 (CHEMBL1796036) Show SMILES COc1ccccc1N1CCN(CCCCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C27H35N3O3/c1-33-25-13-7-6-12-24(25)29-18-16-28(17-19-29)14-8-3-9-15-30-26(31)20-23(21-27(30)32)22-10-4-2-5-11-22/h2,4-7,10-13,23H,3,8-9,14-21H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	30.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418753 (CHEMBL1796034) Show SMILES Clc1ccccc1N1CCN(CCCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C25H30ClN3O2/c26-22-10-4-5-11-23(22)28-16-14-27(15-17-28)12-6-7-13-29-24(30)18-21(19-25(29)31)20-8-2-1-3-9-20/h1-5,8-11,21H,6-7,12-19H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	33.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418771 (CHEMBL100434) Show SMILES CC(C)c1ccc(cc1)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C25H29N5O2/c1-17(2)18-7-9-19(10-8-18)29-14-11-28(12-15-29)13-16-30-24(31)23-22(27-25(30)32)20-5-3-4-6-21(20)26-23/h3-10,17,26H,11-16H2,1-2H3,(H,27,32)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	35.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418754 (CHEMBL1796035) Show SMILES COc1ccc(Cl)cc1N1CCN(CCCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C26H32ClN3O3/c1-33-24-10-9-22(27)19-23(24)29-15-13-28(14-16-29)11-5-6-12-30-25(31)17-21(18-26(30)32)20-7-3-2-4-8-20/h2-4,7-10,19,21H,5-6,11-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	38.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418750 (CHEMBL1796031) Show SMILES Clc1ccccc1N1CCN(CCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C24H28ClN3O2/c25-21-9-4-5-10-22(21)27-15-13-26(14-16-27)11-6-12-28-23(29)17-20(18-24(28)30)19-7-2-1-3-8-19/h1-5,7-10,20H,6,11-18H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	43.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418749 (CHEMBL1796030) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C25H31N3O3/c1-31-23-11-6-5-10-22(23)27-16-14-26(15-17-27)12-7-13-28-24(29)18-21(19-25(28)30)20-8-3-2-4-9-20/h2-6,8-11,21H,7,12-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	45.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418763 (CHEMBL1796044) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC(C)(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C26H33N3O3/c1-26(21-9-4-3-5-10-21)19-24(30)29(25(31)20-26)14-8-13-27-15-17-28(18-16-27)22-11-6-7-12-23(22)32-2/h3-7,9-12H,8,13-20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	51.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418762 (CHEMBL1796043) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC(CC2=O)c2ccc(cc2)[N+]([O-])=O)CC1 Show InChI InChI=1S/C26H32N4O5/c1-35-24-7-3-2-6-23(24)28-16-14-27(15-17-28)12-4-5-13-29-25(31)18-21(19-26(29)32)20-8-10-22(11-9-20)30(33)34/h2-3,6-11,21H,4-5,12-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	53.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418746 (CHEMBL95191) Show SMILES CCC(C)c1ccc(cc1)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C26H31N5O2/c1-3-18(2)19-8-10-20(11-9-19)30-15-12-29(13-16-30)14-17-31-25(32)24-23(28-26(31)33)21-6-4-5-7-22(21)27-24/h4-11,18,27H,3,12-17H2,1-2H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	60.3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418759 (CHEMBL1796040) Show SMILES Clc1ccc(cc1)C1CC(=O)N(CCCN2CCN(CC2)c2ccccc2Cl)C(=O)C1 Show InChI InChI=1S/C24H27Cl2N3O2/c25-20-8-6-18(7-9-20)19-16-23(30)29(24(31)17-19)11-3-10-27-12-14-28(15-13-27)22-5-2-1-4-21(22)26/h1-2,4-9,19H,3,10-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	63.1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418761 (CHEMBL1796042) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC(CC2=O)c2ccc(cc2)[N+]([O-])=O)CC1 Show InChI InChI=1S/C25H30N4O5/c1-34-23-6-3-2-5-22(23)27-15-13-26(14-16-27)11-4-12-28-24(30)17-20(18-25(28)31)19-7-9-21(10-8-19)29(32)33/h2-3,5-10,20H,4,11-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	67.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418758 (CHEMBL1796039) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC(CC2=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C25H30ClN3O3/c1-32-23-6-3-2-5-22(23)28-15-13-27(14-16-28)11-4-12-29-24(30)17-20(18-25(29)31)19-7-9-21(26)10-8-19/h2-3,5-10,20H,4,11-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	69.2	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418760 (CHEMBL1796041) Show SMILES COc1ccccc1N1CCN(CCCCN2C(=O)CC(CC2=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C26H32ClN3O3/c1-33-24-7-3-2-6-23(24)29-16-14-28(15-17-29)12-4-5-13-30-25(31)18-21(19-26(30)32)20-8-10-22(27)11-9-20/h2-3,6-11,21H,4-5,12-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	72.4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418768 (CHEMBL1796049) Show SMILES COc1ccccc1N1CCN(CCCN2C(=O)CC3(CCc4ccccc34)CC2=O)CC1 Show InChI InChI=1S/C27H33N3O3/c1-33-24-10-5-4-9-23(24)29-17-15-28(16-18-29)13-6-14-30-25(31)19-27(20-26(30)32)12-11-21-7-2-3-8-22(21)27/h2-5,7-10H,6,11-20H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	75.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418766 (CHEMBL1796047) Show SMILES COc1ccc(Cl)cc1N1CCN(CCCCN2C(=O)CC(C)(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C27H34ClN3O3/c1-27(21-8-4-3-5-9-21)19-25(32)31(26(33)20-27)13-7-6-12-29-14-16-30(17-15-29)23-18-22(28)10-11-24(23)34-2/h3-5,8-11,18H,6-7,12-17,19-20H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	77.6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418764 (CHEMBL1796045) Show SMILES COc1ccc(Cl)cc1N1CCN(CCCN2C(=O)CC(C)(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C26H32ClN3O3/c1-26(20-7-4-3-5-8-20)18-24(31)30(25(32)19-26)12-6-11-28-13-15-29(16-14-28)22-17-21(27)9-10-23(22)33-2/h3-5,7-10,17H,6,11-16,18-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	97.7	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418772 (CHEMBL330198) Show SMILES CCCCc1ccc(cc1)N1CCN(CCn2c(=O)[nH]c3c4ccccc4[nH]c3c2=O)CC1 Show InChI InChI=1S/C26H31N5O2/c1-2-3-6-19-9-11-20(12-10-19)30-16-13-29(14-17-30)15-18-31-25(32)24-23(28-26(31)33)21-7-4-5-8-22(21)27-24/h4-5,7-12,27H,2-3,6,13-18H2,1H3,(H,28,33)	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	245	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418751 (CHEMBL1796032) Show SMILES COc1ccc(Cl)cc1N1CCN(CCCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C25H30ClN3O3/c1-32-23-9-8-21(26)18-22(23)28-14-12-27(13-15-28)10-5-11-29-24(30)16-20(17-25(29)31)19-6-3-2-4-7-19/h2-4,6-9,18,20H,5,10-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	389	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418748 (CHEMBL1796029) Show SMILES Clc1ccccc1N1CCN(CCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C23H26ClN3O2/c24-20-8-4-5-9-21(20)26-13-10-25(11-14-26)12-15-27-22(28)16-19(17-23(27)29)18-6-2-1-3-7-18/h1-9,19H,10-17H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	631	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418756 (CHEMBL1796037) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC(CC2=O)c2ccc(Cl)cc2)CC1 Show InChI InChI=1S/C24H28ClN3O3/c1-31-22-5-3-2-4-21(22)27-13-10-26(11-14-27)12-15-28-23(29)16-19(17-24(28)30)18-6-8-20(25)9-7-18/h2-9,19H,10-17H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	692	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418767 (CHEMBL1796048) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC3(CCc4ccccc34)CC2=O)CC1 Show InChI InChI=1S/C26H31N3O3/c1-32-23-9-5-4-8-22(23)28-15-12-27(13-16-28)14-17-29-24(30)18-26(19-25(29)31)11-10-20-6-2-3-7-21(20)26/h2-9H,10-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	912	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418747 (CHEMBL1796028) Show SMILES COc1ccccc1N1CCN(CCN2C(=O)CC(CC2=O)c2ccccc2)CC1 Show InChI InChI=1S/C24H29N3O3/c1-30-22-10-6-5-9-21(22)26-14-11-25(12-15-26)13-16-27-23(28)17-20(18-24(27)29)19-7-3-2-4-8-19/h2-10,20H,11-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.32E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair
Alpha-1D adrenergic receptor (Homo sapiens (Human))	BDBM50418757 (CHEMBL1796038) Show SMILES Clc1ccc(cc1)C1CC(=O)N(CCN2CCN(CC2)c2ccccc2Cl)C(=O)C1 Show InChI InChI=1S/C23H25Cl2N3O2/c24-19-7-5-17(6-8-19)18-15-22(29)28(23(30)16-18)14-11-26-9-12-27(13-10-26)21-4-2-1-3-20(21)25/h1-8,18H,9-16H2	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.51E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ di Catania Curated by ChEMBL					Assay Description Displacement of [125I]BE-2254 from human adrenergic Alpha-1D receptor expressed in HEK293 cells				Eur J Med Chem 46: 2676-90 (2011) Article DOI: 10.1016/j.ejmech.2011.03.054 BindingDB Entry DOI: 10.7270/Q25140G9
					More data for this Ligand-Target Pair