Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50027366 (Ketazocine | US10081602, Example Ketazocine | US10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM168148 (US10081602, Example 20 | US10865186, Compound 20 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.86 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM168147 (US10081602, Example 12 | US9688638, 12) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM168148 (US10081602, Example 20 | US10865186, Compound 20 |...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 44.3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM168147 (US10081602, Example 12 | US9688638, 12) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 58.5 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285849 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-{2-[2-(2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 203 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM168150 (US10081602, Example 24 | US10865186, Compound 24 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 494 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285847 ((2S,6R,11R)-3-(Cyclopropylmethyl)-6,11-dimethyl-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 549 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285816 ((2S, 6R, 11R)-3-(Cyclopropylmethyl)-8-({2-[2-(2-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 619 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285848 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-(2,5,8,11,14,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 769 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM168151 (US10081602, Example 25 | US9688638, 25) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 955 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM168149 (US10081602, Example 23 | US10865186, Compound 23 |...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.06E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285851 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-(2,5,8,11,14,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.40E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM168150 (US10081602, Example 24 | US10865186, Compound 24 |...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 1.81E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285850 ((2S,6R,11R)-3-(Cyclopropylmethyl)-6,11-dimethyl-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 2.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM168151 (US10081602, Example 25 | US9688638, 25) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 3.92E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM168149 (US10081602, Example 23 | US10865186, Compound 23 |...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | 7.96E+3 | n/a | n/a | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM50027366 (Ketazocine | US10081602, Example Ketazocine | US10...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Mu-type opioid receptor (Homo sapiens (Human)) | BDBM50027366 (Ketazocine | US10081602, Example Ketazocine | US10...) | PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 8.40 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285849 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-{2-[2-(2-metho...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 879 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285847 ((2S,6R,11R)-3-(Cyclopropylmethyl)-6,11-dimethyl-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.38E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285816 ((2S, 6R, 11R)-3-(Cyclopropylmethyl)-8-({2-[2-(2-me...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 2.68E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285848 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-(2,5,8,11,14,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 3.33E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285851 ((2S,6R,11R)-3-(Cyclopropylmethyl)-8-(2,5,8,11,14,1...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 6.08E+3 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Kappa-type opioid receptor (Homo sapiens (Human)) | BDBM285850 ((2S,6R,11R)-3-(Cyclopropylmethyl)-6,11-dimethyl-8-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 1.28E+4 | n/a | n/a | n/a | n/a | 7.5 | n/a |
Nektar Therapeutics US Patent | Assay Description The binding affinities of certain compounds of the present invention were evaluated using radioligand binding assays in membranes prepared from CHO-K... | US Patent US10081602 (2018) BindingDB Entry DOI: 10.7270/Q2N87CT7 | |||||||||||
More data for this Ligand-Target Pair |