Compile Data Set for Download or QSAR

Found 74 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 7068   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172358 (US9090596, 38) Show SMILES CC(C)c1coc(c1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H29N3O6/c1-13(2)14-9-17(34-10-14)23(25(3)11-33-12-25)27-19-18(21(30)22(19)31)26-16-8-6-7-15(20(16)29)24(32)28(4)5/h6-10,13,23,26-27,29H,11-12H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172368 (US9090596, 48) Show SMILES CN(CC(F)(F)F)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C24H24F3N3O6/c1-12-7-8-15(36-12)21(23(2)10-35-11-23)29-17-16(19(32)20(17)33)28-14-6-4-5-13(18(14)31)22(34)30(3)9-24(25,26)27/h4-8,21,28-29,31H,9-11H2,1-3H3/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	26	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172372 (US9090596, 53) Show SMILES CN1CCN(CC1)S(=O)(=O)c1c(Cl)ccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C25H29ClN4O7S/c1-14-4-7-17(37-14)24(25(2)12-36-13-25)28-19-18(21(32)22(19)33)27-16-6-5-15(26)23(20(16)31)38(34,35)30-10-8-29(3)9-11-30/h4-7,24,27-28,31H,8-13H2,1-3H3/t24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172342 (US9090596, 22) Show SMILES CN(C)S(=O)(=O)c1c(Cl)ccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H24ClN3O7S/c1-11-5-8-14(33-11)21(22(2)9-32-10-22)25-16-15(18(28)19(16)29)24-13-7-6-12(23)20(17(13)27)34(30,31)26(3)4/h5-8,21,24-25,27H,9-10H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172357 (US9090596, 37a | US9090596, 37b) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cc(C)co3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H25N3O6/c1-12-8-15(32-9-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172328 (US9090596, 8) Show SMILES COC(=O)[C@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C27H29N3O8/c1-14-9-10-18(38-14)24(27(2)12-37-13-27)29-20-19(22(32)23(20)33)28-16-7-4-6-15(21(16)31)25(34)30-11-5-8-17(30)26(35)36-3/h4,6-7,9-10,17,24,28-29,31H,5,8,11-13H2,1-3H3/t17-,24+/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	37	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172329 (US9090596, 9) Show SMILES COC(=O)[C@@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C27H29N3O8/c1-14-9-10-18(38-14)24(27(2)12-37-13-27)29-20-19(22(32)23(20)33)28-16-7-4-6-15(21(16)31)25(34)30-11-5-8-17(30)26(35)36-3/h4,6-7,9-10,17,24,28-29,31H,5,8,11-13H2,1-3H3/t17-,24-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172369 (US9090596, 50) Show SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C23H25N3O6/c1-12-8-9-15(32-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172370 (US9090596, 51) Show SMILES CCN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C24H27N3O6/c1-5-27(4)23(31)14-7-6-8-15(19(14)28)25-17-18(21(30)20(17)29)26-22(24(3)11-32-12-24)16-10-9-13(2)33-16/h6-10,22,25-26,28H,5,11-12H2,1-4H3/t22-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172345 (US9090596, 25) Show SMILES CN(C)C(=O)c1scc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C21H23N3O6S/c1-10-5-6-12(30-10)19(21(2)8-29-9-21)23-14-13(16(26)17(14)27)22-11-7-31-18(15(11)25)20(28)24(3)4/h5-7,19,22-23,25H,8-9H2,1-4H3/t19-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	96	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172327 (US9090596, 7) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CCC[C@@H]3C(=O)OC(C)(C)C)c2O)c(=O)c1=O)C1(C)COC1 |r| Show InChI InChI=1S/C30H35N3O8/c1-16-11-12-20(40-16)26(30(5)14-39-15-30)32-22-21(24(35)25(22)36)31-18-9-6-8-17(23(18)34)27(37)33-13-7-10-19(33)28(38)41-29(2,3)4/h6,8-9,11-12,19,26,31-32,34H,7,10,13-15H2,1-5H3/t19-,26?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172332 (US9090596, 12) Show SMILES CC(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C24H26N2O6/c1-12(2)19(27)14-6-5-7-15(20(14)28)25-17-18(22(30)21(17)29)26-23(24(4)10-31-11-24)16-9-8-13(3)32-16/h5-9,12,23,25-26,28H,10-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172323 (US9090596, 3) Show SMILES CCC1(COC1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 Show InChI InChI=1S/C24H27N3O6/c1-5-24(11-32-12-24)22(16-10-9-13(2)33-16)26-18-17(20(29)21(18)30)25-15-8-6-7-14(19(15)28)23(31)27(3)4/h6-10,22,25-26,28H,5,11-12H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172354 (US9090596, 34) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cccs3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H23N3O5S/c1-22(10-30-11-22)20(14-8-5-9-31-14)24-16-15(18(27)19(16)28)23-13-7-4-6-12(17(13)26)21(29)25(2)3/h4-9,20,23-24,26H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	106	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172372 (US9090596, 53) Show SMILES CN1CCN(CC1)S(=O)(=O)c1c(Cl)ccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C25H29ClN4O7S/c1-14-4-7-17(37-14)24(25(2)12-36-13-25)28-19-18(21(32)22(19)33)27-16-6-5-15(26)23(20(16)31)38(34,35)30-10-8-29(3)9-11-30/h4-7,24,27-28,31H,8-13H2,1-3H3/t24-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	115	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172342 (US9090596, 22) Show SMILES CN(C)S(=O)(=O)c1c(Cl)ccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H24ClN3O7S/c1-11-5-8-14(33-11)21(22(2)9-32-10-22)25-16-15(18(28)19(16)29)24-13-7-6-12(23)20(17(13)27)34(30,31)26(3)4/h5-8,21,24-25,27H,9-10H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	117	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172355 (US9090596, 35) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)s3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H25N3O5S/c1-12-8-9-15(32-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	146	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172356 (US9090596, 36) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccco3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H23N3O6/c1-22(10-30-11-22)20(14-8-5-9-31-14)24-16-15(18(27)19(16)28)23-13-7-4-6-12(17(13)26)21(29)25(2)3/h4-9,20,23-24,26H,10-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	198	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172357 (US9090596, 37a | US9090596, 37b) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cc(C)co3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H25N3O6/c1-12-8-15(32-9-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	207	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172347 (US9090596, 27) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cc(C)c(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C24H27N3O6/c1-12-9-16(33-13(12)2)22(24(3)10-32-11-24)26-18-17(20(29)21(18)30)25-15-8-6-7-14(19(15)28)23(31)27(4)5/h6-9,22,25-26,28H,10-11H2,1-5H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	244	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172341 (US9090596, 21) Show SMILES CN(C)S(=O)(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H25N3O7S/c1-12-8-9-14(32-12)21(22(2)10-31-11-22)24-17-16(19(27)20(17)28)23-13-6-5-7-15(18(13)26)33(29,30)25(3)4/h5-9,21,23-24,26H,10-11H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	257	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172334 (US9090596, 14) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CCCC3)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O6/c1-14-8-9-17(34-14)23(25(2)12-33-13-25)27-19-18(21(30)22(19)31)26-16-7-5-6-15(20(16)29)24(32)28-10-3-4-11-28/h5-9,23,26-27,29H,3-4,10-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	262	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172322 (US9090596, 2) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(CF)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H24FN3O6/c1-12-7-8-15(33-12)21(23(9-24)10-32-11-23)26-17-16(19(29)20(17)30)25-14-6-4-5-13(18(14)28)22(31)27(2)3/h4-8,21,25-26,28H,9-11H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	272	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172362 (US9090596, 42) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C#N)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C21H19N3O5/c1-11-6-7-14(29-11)20(21(2)9-28-10-21)24-16-15(18(26)19(16)27)23-13-5-3-4-12(8-22)17(13)25/h3-7,20,23-25H,9-10H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	311	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172369 (US9090596, 50) Show SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C23H25N3O6/c1-12-8-9-15(32-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	312	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172358 (US9090596, 38) Show SMILES CC(C)c1coc(c1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H29N3O6/c1-13(2)14-9-17(34-10-14)23(25(3)11-33-12-25)27-19-18(21(30)22(19)31)26-16-8-6-7-15(20(16)29)24(32)28(4)5/h6-10,13,23,26-27,29H,11-12H2,1-5H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	322	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172340 (US9090596, 20) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccnc2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C19H19N3O5/c1-10-5-6-12(27-10)17(19(2)8-26-9-19)22-14-13(15(23)16(14)24)21-11-4-3-7-20-18(11)25/h3-7,17,21-22H,8-9H2,1-2H3,(H,20,25)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	335	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172325 (US9090596, 5) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CC[C@@H](O)C3)c2O)c(=O)c1=O)C1(C)COC1 |r| Show InChI InChI=1S/C25H27N3O7/c1-13-6-7-17(35-13)23(25(2)11-34-12-25)27-19-18(21(31)22(19)32)26-16-5-3-4-15(20(16)30)24(33)28-9-8-14(29)10-28/h3-7,14,23,26-27,29-30H,8-12H2,1-2H3/t14-,23?/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	341	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172350 (US9090596, 30) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3ccc4OCOc4c3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C25H25N3O7/c1-25(10-33-11-25)23(13-7-8-16-17(9-13)35-12-34-16)27-19-18(21(30)22(19)31)26-15-6-4-5-14(20(15)29)24(32)28(2)3/h4-9,23,26-27,29H,10-12H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	349	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172371 (US9090596, 52) Show SMILES CN(C)C(=O)c1c(Cl)ccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C23H24ClN3O6/c1-11-5-8-14(33-11)21(23(2)9-32-10-23)26-17-16(19(29)20(17)30)25-13-7-6-12(24)15(18(13)28)22(31)27(3)4/h5-8,21,25-26,28H,9-10H2,1-4H3/t21-/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	373	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172339 (US9090596, 19) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccn(C)c2=O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C20H21N3O5/c1-11-6-7-13(28-11)18(20(2)9-27-10-20)22-15-14(16(24)17(15)25)21-12-5-4-8-23(3)19(12)26/h4-8,18,21-22H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	394	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172349 (US9090596, 29) Show SMILES COc1ccc(cc1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O6/c1-25(12-34-13-25)23(14-8-10-15(33-4)11-9-14)27-19-18(21(30)22(19)31)26-17-7-5-6-16(20(17)29)24(32)28(2)3/h5-11,23,26-27,29H,12-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	433	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172348 (US9090596, 28) Show SMILES COc1cccc(c1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O6/c1-25(12-34-13-25)23(14-7-5-8-15(11-14)33-4)27-19-18(21(30)22(19)31)26-17-10-6-9-16(20(17)29)24(32)28(2)3/h5-11,23,26-27,29H,12-13H2,1-4H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	475	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172360 (US9090596, 40) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2ccc(Cl)nc2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C19H18ClN3O5/c1-9-3-5-11(28-9)17(19(2)7-27-8-19)23-14-13(15(24)16(14)25)21-10-4-6-12(20)22-18(10)26/h3-6,17,21,23H,7-8H2,1-2H3,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	502	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172331 (US9090596, 11) Show SMILES CC(O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H24N2O6/c1-11-7-8-15(30-11)21(22(3)9-29-10-22)24-17-16(19(27)20(17)28)23-14-6-4-5-13(12(2)25)18(14)26/h4-8,12,21,23-26H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	549	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172368 (US9090596, 48) Show SMILES CN(CC(F)(F)F)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C24H24F3N3O6/c1-12-7-8-15(36-12)21(23(2)10-35-11-23)29-17-16(19(32)20(17)33)28-14-6-4-5-13(18(14)31)22(34)30(3)9-24(25,26)27/h4-8,21,28-29,31H,9-11H2,1-3H3/t21-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	566	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172328 (US9090596, 8) Show SMILES COC(=O)[C@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C27H29N3O8/c1-14-9-10-18(38-14)24(27(2)12-37-13-27)29-20-19(22(32)23(20)33)28-16-7-4-6-15(21(16)31)25(34)30-11-5-8-17(30)26(35)36-3/h4,6-7,9-10,17,24,28-29,31H,5,8,11-13H2,1-3H3/t17-,24+/m1/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	604	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172335 (US9090596, 15) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CCOCC3)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O7/c1-14-6-7-17(35-14)23(25(2)12-34-13-25)27-19-18(21(30)22(19)31)26-16-5-3-4-15(20(16)29)24(32)28-8-10-33-11-9-28/h3-7,23,26-27,29H,8-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	626	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172370 (US9090596, 51) Show SMILES CCN(C)C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C24H27N3O6/c1-5-27(4)23(31)14-7-6-8-15(19(14)28)25-17-18(21(30)20(17)29)26-22(24(3)11-32-12-24)16-10-9-13(2)33-16/h6-10,22,25-26,28H,5,11-12H2,1-4H3/t22-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	650	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172329 (US9090596, 9) Show SMILES COC(=O)[C@@H]1CCCN1C(=O)c1cccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C27H29N3O8/c1-14-9-10-18(38-14)24(27(2)12-37-13-27)29-20-19(22(32)23(20)33)28-16-7-4-6-15(21(16)31)25(34)30-11-5-8-17(30)26(35)36-3/h4,6-7,9-10,17,24,28-29,31H,5,8,11-13H2,1-3H3/t17-,24-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	666	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172351 (US9090596, 31) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(c2)C(=O)N2CCC(O)C2)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O6/c1-14-6-7-18(34-14)23(25(2)12-33-13-25)27-20-19(21(30)22(20)31)26-16-5-3-4-15(10-16)24(32)28-9-8-17(29)11-28/h3-7,10,17,23,26-27,29H,8-9,11-13H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	716	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172374 (US9090596, 49) Show SMILES CN(C)C(=O)c1cccc(Nc2c(N[C@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C23H25N3O6/c1-12-8-9-15(32-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3/t21-/m1/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	733	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172357 (US9090596, 37a | US9090596, 37b) Show SMILES CN(C)C(=O)c1cccc(Nc2c(NC(c3cc(C)co3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C23H25N3O6/c1-12-8-15(32-9-12)21(23(2)10-31-11-23)25-17-16(19(28)20(17)29)24-14-7-5-6-13(18(14)27)22(30)26(3)4/h5-9,21,24-25,27H,10-11H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	827	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172371 (US9090596, 52) Show SMILES CN(C)C(=O)c1c(Cl)ccc(Nc2c(N[C@@H](c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O |r| Show InChI InChI=1S/C23H24ClN3O6/c1-11-5-8-14(33-11)21(23(2)9-32-10-23)26-17-16(19(29)20(17)30)25-13-7-6-12(24)15(18(13)28)22(31)27(3)4/h5-8,21,25-26,28H,9-10H2,1-4H3/t21-/m0/s1	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	897	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172353 (US9090596, 33) Show SMILES COC(=O)C1CCCN1C(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C27H29N3O8/c1-14-9-10-18(38-14)24(27(2)12-37-13-27)29-20-19(22(32)23(20)33)28-16-7-4-6-15(21(16)31)25(34)30-11-5-8-17(30)26(35)36-3/h4,6-7,9-10,17,24,28-29,31H,5,8,11-13H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	962	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172359 (US9090596, 39) Show SMILES COc1ccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c(O)n1 Show InChI InChI=1S/C20H21N3O6/c1-10-4-6-12(29-10)18(20(2)8-28-9-20)23-15-14(16(24)17(15)25)21-11-5-7-13(27-3)22-19(11)26/h4-7,18,21,23H,8-9H2,1-3H3,(H,22,26)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.04E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 2 (Homo sapiens (Human))	BDBM172326 (US9090596, 6) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CC[C@H](O)C3)c2O)c(=O)c1=O)C1(C)COC1 |r| Show InChI InChI=1S/C25H27N3O7/c1-13-6-7-17(35-13)23(25(2)11-34-12-25)27-19-18(21(31)22(19)32)26-16-5-3-4-15(20(16)30)24(33)28-9-8-14(29)10-28/h3-7,14,23,26-27,29-30H,8-12H2,1-2H3/t14-,23?/m0/s1	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.09E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172323 (US9090596, 3) Show SMILES CCC1(COC1)C(Nc1c(Nc2cccc(C(=O)N(C)C)c2O)c(=O)c1=O)c1ccc(C)o1 Show InChI InChI=1S/C24H27N3O6/c1-5-24(11-32-12-24)22(16-10-9-13(2)33-16)26-18-17(20(29)21(18)30)25-15-8-6-7-14(19(15)28)23(31)27(3)4/h6-10,22,25-26,28H,5,11-12H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.15E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172334 (US9090596, 14) Show SMILES Cc1ccc(o1)C(Nc1c(Nc2cccc(C(=O)N3CCCC3)c2O)c(=O)c1=O)C1(C)COC1 Show InChI InChI=1S/C25H27N3O6/c1-14-8-9-17(34-14)23(25(2)12-33-13-25)27-19-18(21(30)22(19)31)26-16-7-5-6-15(20(16)29)24(32)28-10-3-4-11-28/h5-9,23,26-27,29H,3-4,10-13H2,1-2H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair
C-X-C chemokine receptor type 1 (Homo sapiens (Human))	BDBM172341 (US9090596, 21) Show SMILES CN(C)S(=O)(=O)c1cccc(Nc2c(NC(c3ccc(C)o3)C3(C)COC3)c(=O)c2=O)c1O Show InChI InChI=1S/C22H25N3O7S/c1-12-8-9-14(32-12)21(22(2)10-31-11-22)24-17-16(19(27)20(17)28)23-13-6-5-7-15(18(13)26)33(29,30)25(3)4/h5-9,21,23-24,26H,10-11H2,1-4H3	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	1.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
GALDERMA RESEARCH & DEVELOPMENT US Patent					Assay Description The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors was determined on a functional test of the .beta.-a...				US Patent US9090596 (2015) BindingDB Entry DOI: 10.7270/Q2M04462
					More data for this Ligand-Target Pair

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