Compile Data Set for Download or QSAR

Found 51 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 925   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Estrogen receptor (Homo sapiens (Human))	BDBM299114 ((6S,8S)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...) Show SMILES CC(C)(F)CN1[C@@H](Cc2c(ccc3[nH]ncc23)[C@@]1(C)c1c(F)cc(OCCN2CC(CF)C2)cc1F)C(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299113 ((6S,8S)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...) Show SMILES CC(C)(F)CN1[C@@H](Cc2c(ccc3[nH]ncc23)[C@H]1c1c(F)cc(OCCN2CC(CF)C2)cc1F)C(F)F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.520	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299149 ((6S,8R)-6-(4-(2- (3- (difluoromethyl) azetidin-1- ...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(C)F)c1c(F)cc(OCCN2CC(C2)C(F)F)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.580	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299143 ((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@](C)(N1CC1(F)COC1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299144 ((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...) Show SMILES CC(C)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299141 ((6R,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(4-(...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@](C)(N1CC1(F)CC1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.980	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299148 (6-(2,6-difluoro- 4-(2-(3- (fluoromethyl) azetidin-...) Show SMILES CC(C)(F)CN1C(c2ccc3[nH]ncc3c2CC1(C)C)c1c(F)cc(OCCN2CC(CF)C2)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299131 ((6S,8R)-7-(2,3- difluoro-2- methylpropyl)-6- (4-(2...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(C)(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299158 (3,5-difluoro-4- ((6S,8R)-7-(2- fluoro-2- methylpro...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(C)F)c1c(F)cc(NCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299111 (US10125135, Example 1) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(C)F)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299119 ((6S,8R)-7-((l-fluorocyclopropyl)methyl)-6-(5-(2-(3...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299122 ((6S,8R)-7-(2,2- difluoropropyl)-6- (4-(2-(3- (fluo...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(C)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299136 ((6S,8R)-7-(2,2- difluoropropyl)-6- (2-fluoro-4-(2-...) Show SMILES COc1cc(OCCN2CC(CF)C2)cc(F)c1[C@H]1N(CC(C)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299142 ((6R,8R)-6-(4- (2-(3- (fluoromethyl) azetidin-1- yl...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)COC1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299112 ((6S,8R)-6-(2,6-difluoro-4-(2-(3-(fluoromethyl)azet...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@](C)(N1CC(C)(C)F)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299152 ((6S,8R)-7-(2,2- difluoropropyl)- 6-(5-(2-(3- (fluo...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(C)(F)F)c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299139 ((6R,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...) Show SMILES CC(C)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299133 ((6S,8R)-6-(4-(2- (3- (fluoromethyl) azetidin-1- yl...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299147 (6-(2,6-difluoro- 4-(2-(3- (fluoromethyl) azetidin-...) Show SMILES CC(C)CN1C(c2ccc3[nH]ncc3c2CC1(C)C)c1c(F)cc(OCCN2CC(CF)C2)cc1F Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299118 ((6S,8R)-7-(2,2-difluoroethyl)-6-(4-(2-(3-(fluorome...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299131 ((6S,8R)-7-(2,3- difluoro-2- methylpropyl)-6- (4-(2...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(C)(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299161 ((6S,8R)-6-(3-fluoro-5-(2-(3-(fluoromethyl)azetidin...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)(F)F)c1ncc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299160 ((6S,8R)-6-(5-(2-(3-(fluoromethyl)azetidin-1-yl)eth...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)C(N1CC(F)(F)F)c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299154 ((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]nc(F)c23)[C@H](N1CC1(F)COC1)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299129 ((6S,8R)-7-(2,3- difluoropropyl)- 6-(4-(2-(3- (fluo...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299129 ((6S,8R)-7-(2,3- difluoropropyl)- 6-(4-(2-(3- (fluo...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299155 ((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...) Show SMILES CC(C)CN1[C@H](C)Cc2c(ccc3[nH]nc(F)c23)[C@H]1c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299138 ((6S,8R)-6-(2- fluoro-4-(2-(3- (fluoromethyl) azeti...) Show SMILES COc1cc(OCCN2CC(CF)C2)cc(F)c1[C@H]1N(CC(F)(F)CF)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299145 ((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)CF)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299150 (2-((6S,8R)-7-((1- fluorocyclo- propyl)methyl)- 8-m...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ccc(OCCN2CC(CF)C2)cc1C#N |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299134 ((6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methox...) Show SMILES COc1cc(OCCN2CC(C)C2)ccc1[C@H]1N(CC(C)(C)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299123 ((6S,8R)-6-(4-(2- (3-(fluoromethyl) azetidin-1- yl)...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)(F)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299115 ((6S,8R)-7-(2-fluoro-2-methylpropyl)-6-(4-(2-(3-(fl...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(C)(C)F)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299125 (2,2-difluoro-3- ((6S,8R)-6-(4-(2- (3-(fluoromethyl...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299124 ((6S,8R)-6-(4-(2- (3-(fluoromethyl) azetidin-1- yl)...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC2(F)COC2)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299135 ((6S,8R)-7-(2- fluoro-2- methylpropyl)-6- (2-methox...) Show SMILES COC1CN(CCOc2ccc([C@H]3N(CC(C)(C)F)[C@H](C)Cc4c3ccc3[nH]ncc43)c(OC)c2)C1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299137 (2,2-difluoro-3- ((6S,8R)-6-(2- fluoro-4-(2-(3- (fl...) Show SMILES COc1cc(OCCN2CC(CF)C2)cc(F)c1[C@H]1N(CC(F)(F)CO)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299145 ((6S,8R)-6-(2,6- difluoro-4-(2-(3- (fluoromethyl) a...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)CF)c1c(F)cc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299159 ((6S,8R)-7-(2,2- difluoroethyl)-6- (3-fluoro-5-(2-(...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1ncc(OCCN2CC(CF)C2)cc1F |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299127 ((6S,8R)-7-(2- fluoro-3- methoxy-2- methylpropyl)-6...) Show SMILES COCC(C)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cc1OC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299157 ((6S,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(6-(...) Show SMILES COc1nc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299126 ((6S,8R)-7-(2,2- difluoro-3- methoxypropyl)- 6-(4-(...) Show SMILES COCC(F)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cc1OC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299120 ((6S,8R)-6-(4-(2-(3-(fluoromethyl)azetidin-1-yl)eth...) Show SMILES COc1cc(OCCN2CC(CF)C2)ccc1[C@H]1N(CC(C)C)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299162 ((6S,8R)-7-(2,2-difluoroethyl)-6-(5-(2-(3-(fluorome...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC(F)F)c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299153 ((6-chloro-4-methoxypyridin-3-yl)methanol | US10125...) Show SMILES COc1cc(OCCN2CC(CF)C2)ncc1[C@H]1N(CC2(F)CC2)[C@H](C)Cc2c1ccc1[nH]ncc21 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	6.60	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299156 (7-(2,2- difluoroethyl)- 6-(5-(2-(3- (fluoromethyl)...) Show SMILES CC1(C)Cc2c(ccc3[nH]ncc23)C(N1CC(F)F)c1ccc(OCCN2CC(CF)C2)cn1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299121 ((6S,8R)-7-(2,2-difluoro-3-methoxypropyl)-6-(5-(2-(...) Show SMILES COCC(F)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.90	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299140 ((6R,8R)-7-((1- fluorocyclo- propyl)methyl)- 6-(4-(...) Show SMILES C[C@@H]1Cc2c(ccc3[nH]ncc23)[C@H](N1CC1(F)CC1)c1ccc(OCCN2CC(CF)C2)cc1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.20	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299151 ((6S,8R)-6-(5-(2- (3-(fluoromethyl) azetidin-1- yl)...) Show SMILES CC(C)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cn1 |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.40	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair
Estrogen receptor (Homo sapiens (Human))	BDBM299127 ((6S,8R)-7-(2- fluoro-3- methoxy-2- methylpropyl)-6...) Show SMILES COCC(C)(F)CN1[C@H](C)Cc2c(ccc3[nH]ncc23)[C@H]1c1ccc(OCCN2CC(CF)C2)cc1OC |r| Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	9.70	n/a	n/a	n/a	n/a	n/a	n/a
AstraZeneca AB US Patent					Assay Description The ability of compounds to bind to isolated Estrogen Receptor Alpha Ligand binding domain (ER alpha LBD (GST)) was assessed in competition assays us...				US Patent US10125135 (2018) BindingDB Entry DOI: 10.7270/Q25B04KW
					More data for this Ligand-Target Pair

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