Compile Data Set for Download or QSAR

Found 55 hits Enz. Inhib. hit(s) with all data for assayid = 1 entry = 975   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301418 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-...) Show SMILES CC(c1cn(nn1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H14F4N10/c1-11(15-9-35(34-33-15)16-5-3-2-4-14(16)23)18-13(6-27)17(19-20(28)31-10-32-36(18)19)12-7-29-21(30-8-12)22(24,25)26/h2-5,7-11H,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	51.1	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301473 (1-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES C[C@@H](c1cn(nn1)-c1cc(F)ccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 |r| Show InChI InChI=1S/C21H14F5N9/c1-10(15-8-34(33-32-15)17-4-12(22)2-3-14(17)23)16-5-13(18-19(27)30-9-31-35(16)18)11-6-28-20(29-7-11)21(24,25)26/h2-10H,1H3,(H2,27,30,31)/t10-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	29.2	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301420 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CC(c1cn(nn1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H13F5N10/c1-10(15-8-36(35-34-15)16-3-2-12(23)4-14(16)24)18-13(5-28)17(19-20(29)32-9-33-37(18)19)11-6-30-21(31-7-11)22(25,26)27/h2-4,6-10H,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	14.6	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301421 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H16F4N10/c1-2-13(16-10-36(35-34-16)17-6-4-3-5-15(17)24)19-14(7-28)18(20-21(29)32-11-33-37(19)20)12-8-30-22(31-9-12)23(25,26)27/h3-6,8-11,13H,2H2,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	20.5	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301421 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H16F4N10/c1-2-13(16-10-36(35-34-16)17-6-4-3-5-15(17)24)19-14(7-28)18(20-21(29)32-11-33-37(19)20)12-8-30-22(31-9-12)23(25,26)27/h3-6,8-11,13H,2H2,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3.02	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301423 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F5N10/c1-2-13(16-9-37(36-35-16)17-4-3-12(24)5-15(17)25)19-14(6-29)18(20-21(30)33-10-34-38(19)20)11-7-31-22(32-8-11)23(26,27)28/h3-5,7-10,13H,2H2,1H3,(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5.48	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301423 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F5N10/c1-2-13(16-9-37(36-35-16)17-4-3-12(24)5-15(17)25)19-14(6-29)18(20-21(30)33-10-34-38(19)20)11-7-31-22(32-8-11)23(26,27)28/h3-5,7-10,13H,2H2,1H3,(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	33.5	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301425 (4-amino-7-{1-[1-(2,5-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CCC(c1cn(nn1)-c1cc(F)ccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F5N10/c1-2-13(16-9-37(36-35-16)17-5-12(24)3-4-15(17)25)19-14(6-29)18(20-21(30)33-10-34-38(19)20)11-7-31-22(32-8-11)23(26,27)28/h3-5,7-10,13H,2H2,1H3,(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	13	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301426 (4-amino-7-{1-[1-(3,4-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)c(F)c1)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F5N10/c1-2-13(17-9-37(36-35-17)12-3-4-15(24)16(25)5-12)19-14(6-29)18(20-21(30)33-10-34-38(19)20)11-7-31-22(32-8-11)23(26,27)28/h3-5,7-10,13H,2H2,1H3,(H2,30,33,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	28.4	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301427 (4-amino-7-{1-[1-(propan-2-yl)-1H-pyrazol-4-yl]prop...) Show SMILES CCC(c1cnn(c1)C(C)C)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H20F3N9/c1-4-14(13-8-30-32(9-13)11(2)3)17-15(5-25)16(18-19(26)29-10-31-33(17)18)12-6-27-20(28-7-12)21(22,23)24/h6-11,14H,4H2,1-3H3,(H2,26,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	48	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301427 (4-amino-7-{1-[1-(propan-2-yl)-1H-pyrazol-4-yl]prop...) Show SMILES CCC(c1cnn(c1)C(C)C)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H20F3N9/c1-4-14(13-8-30-32(9-13)11(2)3)17-15(5-25)16(18-19(26)29-10-31-33(17)18)12-6-27-20(28-7-12)21(22,23)24/h6-11,14H,4H2,1-3H3,(H2,26,29,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.96	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301429 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]e...) Show SMILES CC(c1cnn(c1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F4N9/c1-12(14-9-33-35(10-14)17-5-3-2-4-16(17)24)19-15(6-28)18(20-21(29)32-11-34-36(19)20)13-7-30-22(31-8-13)23(25,26)27/h2-5,7-12H,1H3,(H2,29,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301429 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]e...) Show SMILES CC(c1cnn(c1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H15F4N9/c1-12(14-9-33-35(10-14)17-5-3-2-4-16(17)24)19-15(6-28)18(20-21(29)32-11-34-36(19)20)13-7-30-22(31-8-13)23(25,26)27/h2-5,7-12H,1H3,(H2,29,32,34)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.420	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301431 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]p...) Show SMILES CCC(c1cnn(c1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C24H17F4N9/c1-2-15(14-10-34-36(11-14)18-6-4-3-5-17(18)25)20-16(7-29)19(21-22(30)33-12-35-37(20)21)13-8-31-23(32-9-13)24(26,27)28/h3-6,8-12,15H,2H2,1H3,(H2,30,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301431 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-pyrazol-4-yl]p...) Show SMILES CCC(c1cnn(c1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C24H17F4N9/c1-2-15(14-10-34-36(11-14)18-6-4-3-5-17(18)25)20-16(7-29)19(21-22(30)33-12-35-37(20)21)13-8-31-23(32-9-13)24(26,27)28/h3-6,8-12,15H,2H2,1H3,(H2,30,33,35)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.200	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301433 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-pyrazol-4-...) Show SMILES CCC(c1cnn(c1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C24H16F5N9/c1-2-15(13-9-35-37(10-13)18-4-3-14(25)5-17(18)26)20-16(6-30)19(21-22(31)34-11-36-38(20)21)12-7-32-23(33-8-12)24(27,28)29/h3-5,7-11,15H,2H2,1H3,(H2,31,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.420	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301433 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-pyrazol-4-...) Show SMILES CCC(c1cnn(c1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C24H16F5N9/c1-2-15(13-9-35-37(10-13)18-4-3-14(25)5-17(18)26)20-16(6-30)19(21-22(31)34-11-36-38(20)21)12-7-32-23(33-8-12)24(27,28)29/h3-5,7-11,15H,2H2,1H3,(H2,31,34,36)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	3	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301435 (4-amino-7-{1-[3-(2-fluorophenyl)-1,2-oxazol-5-yl]e...) Show SMILES CC(c1cc(no1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H14F4N8O/c1-11(17-6-16(34-36-17)13-4-2-3-5-15(13)24)19-14(7-28)18(20-21(29)32-10-33-35(19)20)12-8-30-22(31-9-12)23(25,26)27/h2-6,8-11H,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.67	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301435 (4-amino-7-{1-[3-(2-fluorophenyl)-1,2-oxazol-5-yl]e...) Show SMILES CC(c1cc(no1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H14F4N8O/c1-11(17-6-16(34-36-17)13-4-2-3-5-15(13)24)19-14(7-28)18(20-21(29)32-10-33-35(19)20)12-8-30-22(31-9-12)23(25,26)27/h2-6,8-11H,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	5	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301437 (4-Amino-7-{1-[1-(2,4-difluorophenyl)-1H-pyrazol-4-...) Show SMILES C[C@H](c1cnn(c1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 |r| Show InChI InChI=1S/C23H14F5N9/c1-11(13-8-34-36(9-13)17-3-2-14(24)4-16(17)25)19-15(5-29)18(20-21(30)33-10-35-37(19)20)12-6-31-22(32-7-12)23(26,27)28/h2-4,6-11H,1H3,(H2,30,33,35)/t11-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	8.94	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301438 (4-amino-7-{(1R)-1-[1-(2,4-difluorophenyl)-1H-pyraz...) Show SMILES C[C@@H](c1cnn(c1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 |r| Show InChI InChI=1S/C23H14F5N9/c1-11(13-8-34-36(9-13)17-3-2-14(24)4-16(17)25)19-15(5-29)18(20-21(30)33-10-35-37(19)20)12-6-31-22(32-7-12)23(26,27)28/h2-4,6-11H,1H3,(H2,30,33,35)/t11-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.660	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301439 (4-amino-7-{[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-...) Show SMILES Nc1ncnn2c(Cc3cn(nn3)-c3ccccc3F)c(C#N)c(-c3cnc(nc3)C(F)(F)F)c12 Show InChI InChI=1S/C21H12F4N10/c22-14-3-1-2-4-15(14)34-9-12(32-33-34)5-16-13(6-26)17(18-19(27)30-10-31-35(16)18)11-7-28-20(29-8-11)21(23,24)25/h1-4,7-10H,5H2,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	27.1	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301420 (4-amino-7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-tria...) Show SMILES CC(c1cn(nn1)-c1ccc(F)cc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H13F5N10/c1-10(15-8-36(35-34-15)16-3-2-12(23)4-14(16)24)18-13(5-28)17(19-20(29)32-9-33-37(18)19)11-6-30-21(31-7-11)22(25,26)27/h2-4,6-10H,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	20.9	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301421 (4-amino-7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1c(C#N)c(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C23H16F4N10/c1-2-13(16-10-36(35-34-16)17-6-4-3-5-15(17)24)19-14(7-28)18(20-21(29)32-11-33-37(19)20)12-8-30-22(31-9-12)23(25,26)27/h3-6,8-11,13H,2H2,1H3,(H2,29,32,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.86	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301442 (4-amino-7-{[1-(2-fluorophenyl)-1H-pyrazol-4-yl]met...) Show SMILES Nc1ncnn2c(Cc3cnn(c3)-c3ccccc3F)c(C#N)c(-c3cnc(nc3)C(F)(F)F)c12 Show InChI InChI=1S/C22H13F4N9/c23-15-3-1-2-4-16(15)34-10-12(7-32-34)5-17-14(6-27)18(19-20(28)31-11-33-35(17)19)13-8-29-21(30-9-13)22(24,25)26/h1-4,7-11H,5H2,(H2,28,31,33)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	0.860	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301443 (4-amino-5-[2-(difluoromethyl)pyrimidin-5-yl]-7-{[1...) Show SMILES Nc1ncnn2c(Cc3cnn(c3)-c3ccccc3F)c(C#N)c(-c3cnc(nc3)C(F)F)c12 Show InChI InChI=1S/C22H14F3N9/c23-15-3-1-2-4-16(15)33-10-12(7-31-33)5-17-14(6-26)18(19-21(27)30-11-32-34(17)19)13-8-28-22(20(24)25)29-9-13/h1-4,7-11,20H,5H2,(H2,27,30,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.05	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301444 (4-Amino-7-{[3-(2-fluorophenyl)-1,2-oxazol-5-yl]met...) Show SMILES Nc1ncnn2c(Cc3cc(no3)-c3ccccc3F)c(C#N)c(-c3cnc(nc3)C(F)(F)F)c12 Show InChI InChI=1S/C22H12F4N8O/c23-15-4-2-1-3-13(15)16-5-12(35-33-16)6-17-14(7-27)18(19-20(28)31-10-32-34(17)19)11-8-29-21(30-9-11)22(24,25)26/h1-5,8-10H,6H2,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301445 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]eth...) Show SMILES CC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H15F4N9/c1-11(15-9-33(32-31-15)16-5-3-2-4-14(16)22)17-6-13(18-19(26)29-10-30-34(17)18)12-7-27-20(28-8-12)21(23,24)25/h2-11H,1H3,(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	171	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301445 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]eth...) Show SMILES CC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H15F4N9/c1-11(15-9-33(32-31-15)16-5-3-2-4-14(16)22)17-6-13(18-19(26)29-10-30-34(17)18)12-7-27-20(28-8-12)21(23,24)25/h2-11H,1H3,(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.48	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301447 (7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CC(c1cn(nn1)-c1ccc(F)cc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H14F5N9/c1-10(15-8-34(33-32-15)16-3-2-12(22)4-14(16)23)17-5-13(18-19(27)30-9-31-35(17)18)11-6-28-20(29-7-11)21(24,25)26/h2-10H,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	225	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301447 (7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CC(c1cn(nn1)-c1ccc(F)cc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H14F5N9/c1-10(15-8-34(33-32-15)16-3-2-12(22)4-14(16)23)17-5-13(18-19(27)30-9-31-35(17)18)11-6-28-20(29-7-11)21(24,25)26/h2-10H,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	7.48	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301449 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H17F4N9/c1-2-13(16-10-34(33-32-16)17-6-4-3-5-15(17)23)18-7-14(19-20(27)30-11-31-35(18)19)12-8-28-21(29-9-12)22(24,25)26/h3-11,13H,2H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301449 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H17F4N9/c1-2-13(16-10-34(33-32-16)17-6-4-3-5-15(17)23)18-7-14(19-20(27)30-11-31-35(18)19)12-8-28-21(29-9-12)22(24,25)26/h3-11,13H,2H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	36.6	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301451 (7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)cc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(16-9-35(34-33-16)17-4-3-12(23)5-15(17)24)18-6-14(19-20(28)31-10-32-36(18)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	115	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301451 (7-{1-[1-(2,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)cc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(16-9-35(34-33-16)17-4-3-12(23)5-15(17)24)18-6-14(19-20(28)31-10-32-36(18)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	2	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301453 (7-{1-[1-(2,5-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1cc(F)ccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(16-9-35(34-33-16)18-5-12(23)3-4-15(18)24)17-6-14(19-20(28)31-10-32-36(17)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	73.7	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301453 (7-{1-[1-(2,5-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1cc(F)ccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(16-9-35(34-33-16)18-5-12(23)3-4-15(18)24)17-6-14(19-20(28)31-10-32-36(17)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	9.95	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301455 (7-{1-[1-(3,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)c(F)c1)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(17-9-35(34-33-17)12-3-4-15(23)16(24)5-12)18-6-14(19-20(28)31-10-32-36(18)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	19.3	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301455 (7-{1-[1-(3,4-difluorophenyl)-1H-1,2,3-triazol-4-yl...) Show SMILES CCC(c1cn(nn1)-c1ccc(F)c(F)c1)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H16F5N9/c1-2-13(17-9-35(34-33-17)12-3-4-15(23)16(24)5-12)18-6-14(19-20(28)31-10-32-36(18)19)11-7-29-21(30-8-11)22(25,26)27/h3-10,13H,2H2,1H3,(H2,28,31,32)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	177	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301457 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CC[C@H](c1cn(nn1)-c1ccccc1F)c1cc(-c2cncnc2OC)c2c(N)ncnn12 |r| Show InChI InChI=1S/C22H20FN9O/c1-3-13(17-10-31(30-29-17)18-7-5-4-6-16(18)23)19-8-14(15-9-25-11-27-22(15)33-2)20-21(24)26-12-28-32(19)20/h4-13H,3H2,1-2H3,(H2,24,26,28)/t13-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	10.4	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301458 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CC[C@@H](c1cn(nn1)-c1ccccc1F)c1cc(-c2cncnc2OC)c2c(N)ncnn12 |r| Show InChI InChI=1S/C22H20FN9O/c1-3-13(17-10-31(30-29-17)18-7-5-4-6-16(18)23)19-8-14(15-9-25-11-27-22(15)33-2)20-21(24)26-12-28-32(19)20/h4-13H,3H2,1-2H3,(H2,24,26,28)/t13-/m0/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	123	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301459 (1-{4-amino-5-[2-(trifluoromethyl)pyrimidin-5-yl]py...) Show SMILES CC(O)(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C21H15F4N9O/c1-20(35,15-9-33(32-31-15)14-5-3-2-4-13(14)22)16-6-12(17-18(26)29-10-30-34(16)17)11-7-27-19(28-8-11)21(23,24)25/h2-10,35H,1H3,(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	147	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301449 (7-{1-[1-(2-fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnn12 Show InChI InChI=1S/C22H17F4N9/c1-2-13(16-10-34(33-32-16)17-6-4-3-5-15(17)23)18-7-14(19-20(27)30-11-31-35(18)19)12-8-28-21(29-9-12)22(24,25)26/h3-11,13H,2H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	4.93	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301462 (7-{1-[1-(2-Fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)c1cc(-c2cncnc2OC)c2c(N)ncnn12 Show InChI InChI=1S/C22H20FN9O/c1-3-13(17-10-31(30-29-17)18-7-5-4-6-16(18)23)19-8-14(15-9-25-11-27-22(15)33-2)20-21(24)26-12-28-32(19)20/h4-13H,3H2,1-2H3,(H2,24,26,28)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	16	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301463 (BDBM301464 | US10131670, Example 87 | {1-[1-(2-Flu...) Show SMILES CCC(c1cnn(c1)-c1ccccc1F)n1nc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H17F4N9/c1-2-15(13-9-32-34(10-13)16-6-4-3-5-14(16)23)35-20-17(19(27)30-11-31-20)18(33-35)12-7-28-21(29-8-12)22(24,25)26/h3-11,15H,2H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	1.53	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301463 (BDBM301464 | US10131670, Example 87 | {1-[1-(2-Flu...) Show SMILES CCC(c1cnn(c1)-c1ccccc1F)n1nc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C22H17F4N9/c1-2-15(13-9-32-34(10-13)16-6-4-3-5-14(16)23)35-20-17(19(27)30-11-31-20)18(33-35)12-7-28-21(29-8-12)22(24,25)26/h3-11,15H,2H2,1H3,(H2,27,30,31)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301465 (1-{1-[1-(2-Fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)n1nc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C21H16F4N10/c1-2-14(13-9-34(33-31-13)15-6-4-3-5-12(15)22)35-19-16(18(26)29-10-30-19)17(32-35)11-7-27-20(28-8-11)21(23,24)25/h3-10,14H,2H2,1H3,(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	189	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301465 (1-{1-[1-(2-Fluorophenyl)-1H-1,2,3-triazol-4-yl]pro...) Show SMILES CCC(c1cn(nn1)-c1ccccc1F)n1nc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnc12 Show InChI InChI=1S/C21H16F4N10/c1-2-14(13-9-34(33-31-13)15-6-4-3-5-12(15)22)35-19-16(18(26)29-10-30-19)17(32-35)11-7-27-20(28-8-11)21(23,24)25/h3-10,14H,2H2,1H3,(H2,26,29,30)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	31.5	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301467 (5-(4-Chlorophenyl)-7-{[1-(2-fluorophenyl)-1H-1,2,3...) Show SMILES Nc1ncnn2c(Cc3cn(nn3)-c3ccccc3F)nc(-c3ccc(Cl)cc3)c12 Show InChI InChI=1S/C20H14ClFN8/c21-13-7-5-12(6-8-13)18-19-20(23)24-11-25-30(19)17(26-18)9-14-10-29(28-27-14)16-4-2-1-3-15(16)22/h1-8,10-11H,9H2,(H2,23,24,25)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	116	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair
Cystic fibrosis transmembrane conductance regulator (Homo sapiens (Human))	BDBM301468 (1-[1-(1-phenyl-1H-1,2,3-triazol-4-yl)propyl]-3-[2-...) Show SMILES CC[C@H](c1cn(nn1)-c1ccccc1)n1nc(-c2cnc(nc2)C(F)(F)F)c2c(N)ncnc12 |r| Show InChI InChI=1S/C21H17F3N10/c1-2-15(14-10-33(32-30-14)13-6-4-3-5-7-13)34-19-16(18(25)28-11-29-19)17(31-34)12-8-26-20(27-9-12)21(22,23)24/h3-11,15H,2H2,1H3,(H2,25,28,29)/t15-/m1/s1	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	74.4	n/a	n/a	n/a	n/a
CYSTIC FIBROSIS FOUNDATION THERAPEUTICS, INC. US Patent					Assay Description Primary cystic fibrosis human bronchial epithelial (CF hBE) cells were expanded and cultured according to published methods (Neuberger et al., Ch. 4 ...				US Patent US10131670 (2018) BindingDB Entry DOI: 10.7270/Q29025VF
					More data for this Ligand-Target Pair

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