Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidylate synthase (Lactobacillus casei) | BDBM50008291 (2-{4-[(2-Amino-4-oxo-1,4-dihydro-pteridin-6-ylmeth...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | n/a | n/a | 3.90E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Southern Research Institute Curated by ChEMBL | Assay Description The compound was tested for its inhibitory activity (IC50) against thymidylate synthase(TS) derived from L. casei | J Med Chem 35: 332-7 (1992) BindingDB Entry DOI: 10.7270/Q2N58KBS | |||||||||||
More data for this Ligand-Target Pair |