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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with all data for assayid = 2 entry = 50048047   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Arachidonate 5-lipoxygenase-activating protein


(Homo sapiens (Human))		BDBM50202473
PNG
(CHEMBL3954390)
Show SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2cc(ccc2n1Cc1ccccc1Cl)C#N
Show InChI InChI=1S/C27H26ClN3/c1-18(2)14-20-8-11-22(12-9-20)19(3)27-30-25-15-21(16-29)10-13-26(25)31(27)17-23-6-4-5-7-24(23)28/h4-13,15,18-19H,14,17H2,1-3H3
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Article
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n/an/a 26n/an/an/an/an/an/a



Gazi University

Curated by ChEMBL


Assay Description
Inhibition of FLAP in human monocytes assessed as suppression of A23187-stimulated 5-LO product formation preincubated for 15 mins followed by A23187...

Eur J Med Chem 122: 510-519 (2016)


Article DOI: 10.1016/j.ejmech.2016.07.004
BindingDB Entry DOI: 10.7270/Q2H41TCW
More data for this
Ligand-Target Pair