Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2C8 (Homo sapiens (Human)) | BDBM50397663 (CHEMBL2181817) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem | Article PubMed | 5.20E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Celgene Corporation Curated by ChEMBL | Assay Description Inhibition of CYP2C8 in human liver microsomes using paclitaxel as substrate preincubated for 2 to 40 mins followed by NADPH-generating system additi... | J Med Chem 60: 8691-8705 (2017) Article DOI: 10.1021/acs.jmedchem.7b00510 BindingDB Entry DOI: 10.7270/Q2TT4T34 | |||||||||||
More data for this Ligand-Target Pair |