Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50161093 ((R)-2-chloro-6-(2-hydroxy-3-(2-methyl-1-(naphthale...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 0.0450 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50175387 ((R)-2-(2-hydroxy-3-(2-methyl-1-(naphthalen-2-yl)pr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 0.100 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50268077 ((S)-4-(2-hydroxy-3-(1-(4-methoxyphenyl)-2-methylpr...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.30 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50378146 (CHEMBL1204009) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50299546 (3-{3-Cyano-4-[((2R)-3-{[1,1-dimethyl-2-(2-naphthal...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | >50 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cytochrome P450 2D6 (Homo sapiens (Human)) | BDBM50299545 (3-{4-[((2R)-3-{[1,1-Dimethyl-2-(2-naphthalenyl)eth...) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 52 | n/a | n/a | n/a | n/a | n/a | n/a |
GlaxoSmithKline Curated by ChEMBL | Assay Description Inhibition of CYP2D6 | J Med Chem 52: 6599-605 (2009) Article DOI: 10.1021/jm900563e BindingDB Entry DOI: 10.7270/Q2WM1FB4 | |||||||||||
More data for this Ligand-Target Pair |