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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with all data for assayid = 8 entry = 50015172   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2


(Homo sapiens (Human))
BDBM50583442
PNG
(CHEMBL5077096)
Show SMILES Cc1cnc(Nc2cnn(c2)C(F)F)nc1N1CCC2(CCNC2=O)CC1
PDB

UniProtKB/SwissProt

antibodypedia
antibodypedia
GoogleScholar
AffyNet 
Purchase

MCE
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 299n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of JAK2/TYK2 signalling in human PBMC assessed as inhibition of IL-23 stimulated phosphorylation of STAT3 preincubated for 60 mins followe...


Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01137
BindingDB Entry DOI: 10.7270/Q2KK9GQC
More data for this
Ligand-Target Pair