Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Non-receptor tyrosine-protein kinase TYK2/Tyrosine-protein kinase JAK2 (Homo sapiens (Human)) | BDBM50583442 (CHEMBL5077096) | PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 299 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of JAK2/TYK2 signalling in human PBMC assessed as inhibition of IL-23 stimulated phosphorylation of STAT3 preincubated for 60 mins followe... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01137 BindingDB Entry DOI: 10.7270/Q2KK9GQC | |||||||||||
More data for this Ligand-Target Pair |