Compile Data Set for Download or QSAR

Found 26 hits of ec50 data for polymerid = 2041,2051   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM19993 (CHEMBL62136 | N-[4-(1,1,1,3,3,3-hexafluoro-2-hydro...) Show SMILES OC(c1ccc(cc1)N(CC(F)(F)F)S(=O)(=O)c1ccccc1)(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C17H12F9NO3S/c18-14(19,20)10-27(31(29,30)13-4-2-1-3-5-13)12-8-6-11(7-9-12)15(28,16(21,22)23)17(24,25)26/h1-9,28H,10H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	DrugBank PDB Article PubMed	n/a	n/a	13	n/a	140	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20001 (2-{4-[({3-[3-benzyl-8-(trifluoromethyl)quinolin-4-...) Show SMILES OC(=O)Cc1ccc(CNc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C32H25F3N2O2/c33-32(34,35)28-11-5-10-27-30(25(20-37-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)36-19-23-14-12-22(13-15-23)17-29(38)39/h1-15,18,20,36H,16-17,19H2,(H,38,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	8	n/a	160	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20000 (2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...) Show SMILES OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	9.5	n/a	238	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM20000 (2-(4-{3-[3-benzyl-8-(trifluoromethyl)quinolin-4-yl...) Show SMILES OC(=O)Cc1ccc(COc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)cc1 Show InChI InChI=1S/C32H24F3NO3/c33-32(34,35)28-11-5-10-27-30(25(19-36-31(27)28)16-21-6-2-1-3-7-21)24-8-4-9-26(18-24)39-20-23-14-12-22(13-15-23)17-29(37)38/h1-15,18-19H,16-17,20H2,(H,37,38)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL KEGG PC cid PC sid PDB UniChem Patents Similars	Article PubMed	n/a	n/a	10	n/a	240	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35107 (biarylether amide quinoline, 4g) Show SMILES FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCOCC2)c1 Show InChI InChI=1S/C34H27F3N2O3/c35-34(36,37)30-14-6-13-29-31(26(22-38-32(29)30)19-23-7-2-1-3-8-23)24-9-4-11-27(20-24)42-28-12-5-10-25(21-28)33(40)39-15-17-41-18-16-39/h1-14,20-22H,15-19H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	345	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35105 (biarylether amide quinoline, 4e) Show SMILES FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCCC2)c1 Show InChI InChI=1S/C34H27F3N2O2/c35-34(36,37)30-16-8-15-29-31(26(22-38-32(29)30)19-23-9-2-1-3-10-23)24-11-6-13-27(20-24)41-28-14-7-12-25(21-28)33(40)39-17-4-5-18-39/h1-3,6-16,20-22H,4-5,17-19H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	435	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35106 (biarylether amide quinoline, 4f) Show SMILES FC(F)(F)c1cccc2c(c(Cc3ccccc3)cnc12)-c1cccc(Oc2cccc(c2)C(=O)N2CCCCC2)c1 Show InChI InChI=1S/C35H29F3N2O2/c36-35(37,38)31-17-9-16-30-32(27(23-39-33(30)31)20-24-10-3-1-4-11-24)25-12-7-14-28(21-25)42-29-15-8-13-26(22-29)34(41)40-18-5-2-6-19-40/h1,3-4,7-17,21-23H,2,5-6,18-20H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	20	n/a	477	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM19992 (2-[3-[3-[[2-chloro-3-(trifluoromethyl)phenyl]methy...) Show SMILES OC(=O)Cc1cccc(OCCCN(CC(c2ccccc2)c2ccccc2)Cc2cccc(c2Cl)C(F)(F)F)c1 Show InChI InChI=1S/C33H31ClF3NO3/c34-32-27(15-8-17-30(32)33(35,36)37)22-38(18-9-19-41-28-16-7-10-24(20-28)21-31(39)40)23-29(25-11-3-1-4-12-25)26-13-5-2-6-14-26/h1-8,10-17,20,29H,9,18-19,21-23H2,(H,39,40)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	100	n/a	660	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair				3D Structure (crystal)
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35104 (biarylether amide quinoline, 4d) Show SMILES CCN(CC)C(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C34H29F3N2O2/c1-3-39(4-2)33(40)25-14-9-16-28(21-25)41-27-15-8-13-24(20-27)31-26(19-23-11-6-5-7-12-23)22-38-32-29(31)17-10-18-30(32)34(35,36)37/h5-18,20-22H,3-4,19H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	12	n/a	675	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35115 (biarylether amide quinoline, 4p) Show SMILES Cc1cnc2c(Cl)cccc2c1-c1cccc(Oc2cccc(c2)C(=O)N2CCOCC2)c1 Show InChI InChI=1S/C27H23ClN2O3/c1-18-17-29-26-23(9-4-10-24(26)28)25(18)19-5-2-7-21(15-19)33-22-8-3-6-20(16-22)27(31)30-11-13-32-14-12-30/h2-10,15-17H,11-14H2,1H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	158	n/a	1.24E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35108 (biarylether amide quinoline, 4i) Show SMILES CNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 Show InChI InChI=1S/C24H19ClN2O2/c1-15-14-27-23-20(10-5-11-21(23)25)22(15)16-6-3-8-18(12-16)29-19-9-4-7-17(13-19)24(28)26-2/h3-14H,1-2H3,(H,26,28)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	125	n/a	1.31E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35110 (biarylether amide quinoline, 4k) Show SMILES CCCNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 Show InChI InChI=1S/C26H23ClN2O2/c1-3-13-28-26(30)19-8-5-10-21(15-19)31-20-9-4-7-18(14-20)24-17(2)16-29-25-22(24)11-6-12-23(25)27/h4-12,14-16H,3,13H2,1-2H3,(H,28,30)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	280	n/a	1.63E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26065 (2-[(2,4-dimethylphenyl)methyl]-3-(4-fluorophenyl)-...) Show SMILES Cc1ccc(Cn2nc3c(cccc3c2-c2ccc(F)cc2)C(F)(F)F)c(C)c1 Show InChI InChI=1S/C23H18F4N2/c1-14-6-7-17(15(2)12-14)13-29-22(16-8-10-18(24)11-9-16)19-4-3-5-20(21(19)28-29)23(25,26)27/h3-12H,13H2,1-2H3	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	78	n/a	1.81E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35109 (biarylether amide quinoline, 4j) Show SMILES CCNC(=O)c1cccc(Oc2cccc(c2)-c2c(C)cnc3c(Cl)cccc23)c1 Show InChI InChI=1S/C25H21ClN2O2/c1-3-27-25(29)18-8-5-10-20(14-18)30-19-9-4-7-17(13-19)23-16(2)15-28-24-21(23)11-6-12-22(24)26/h4-15H,3H2,1-2H3,(H,27,29)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	272	n/a	2.10E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM35102 (biarylether amide quinoline, 4b) Show SMILES CCCNC(=O)c1cccc(Oc2cccc(c2)-c2c(Cc3ccccc3)cnc3c(cccc23)C(F)(F)F)c1 Show InChI InChI=1S/C33H27F3N2O2/c1-2-17-37-32(39)24-12-7-14-27(20-24)40-26-13-6-11-23(19-26)30-25(18-22-9-4-3-5-10-22)21-38-31-28(30)15-8-16-29(31)33(34,35)36/h3-16,19-21H,2,17-18H2,1H3,(H,37,39)	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	91	n/a	2.71E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				Bioorg Med Chem 17: 1663-70 (2009) Article DOI: 10.1016/j.bmc.2008.12.048 BindingDB Entry DOI: 10.7270/Q2QR4VGV
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26064 (2-benzyl-3-aryl-7-trifluoromethylindazole, 5 | 2-b...) Show SMILES FC(F)(F)c1cccc2c(-c3ccccc3)n(Cc3ccccc3)nc12 Show InChI InChI=1S/C21H15F3N2/c22-21(23,24)18-13-7-12-17-19(18)25-26(14-15-8-3-1-4-9-15)20(17)16-10-5-2-6-11-16/h1-13H,14H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	279	n/a	4.27E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26068 (2-[(2-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(t...) Show SMILES Fc1ccc(cc1)-c1n(Cc2ccccc2Cl)nc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C21H13ClF4N2/c22-18-7-2-1-4-14(18)12-28-20(13-8-10-15(23)11-9-13)16-5-3-6-17(19(16)27-28)21(24,25)26/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	297	n/a	5.02E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26067 (3-(4-fluorophenyl)-2-[(2-fluorophenyl)methyl]-7-(t...) Show SMILES Fc1ccc(cc1)-c1n(Cc2ccccc2F)nc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C21H13F5N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	248	n/a	6.10E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26066 (2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-fluorophe...) Show SMILES Fc1ccc(cc1)-c1n(Cc2ccc(F)cc2Cl)nc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C21H12ClF5N2/c22-18-10-15(24)9-6-13(18)11-29-20(12-4-7-14(23)8-5-12)16-2-1-3-17(19(16)28-29)21(25,26)27/h1-10H,11H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	179	n/a	6.66E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26069 (2-benzyl-3-aryl-7-trifluoromethylindazole, 15 | 3-...) Show SMILES Fc1ccc(Cn2nc3c(cccc3c2-c2ccc(F)cc2)C(F)(F)F)cc1 Show InChI InChI=1S/C21H13F5N2/c22-15-8-4-13(5-9-15)12-28-20(14-6-10-16(23)11-7-14)17-2-1-3-18(19(17)27-28)21(24,25)26/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	317	n/a	8.40E+3	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26070 (2-[(4-chlorophenyl)methyl]-3-(4-fluorophenyl)-7-(t...) Show SMILES Fc1ccc(cc1)-c1n(Cc2ccc(Cl)cc2)nc2c(cccc12)C(F)(F)F Show InChI InChI=1S/C21H13ClF4N2/c22-15-8-4-13(5-9-15)12-28-20(14-6-10-16(23)11-7-14)17-2-1-3-18(19(17)27-28)21(24,25)26/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	401	n/a	1.28E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26071 (2-[(4-chloro-2-fluorophenyl)methyl]-3-(4-chlorophe...) Show SMILES Fc1cc(Cl)ccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C21H12Cl2F4N2/c22-14-7-4-12(5-8-14)20-16-2-1-3-17(21(25,26)27)19(16)28-29(20)11-13-6-9-15(23)10-18(13)24/h1-10H,11H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	260	n/a	1.33E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26074 (2-benzyl-3-aryl-7-trifluoromethylindazole, 20 | 3-...) Show SMILES Fc1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C21H13ClF4N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	304	n/a	1.34E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26072 (2-[(2-chloro-4-fluorophenyl)methyl]-3-(4-chlorophe...) Show SMILES Fc1ccc(Cn2nc3c(cccc3c2-c2ccc(Cl)cc2)C(F)(F)F)c(Cl)c1 Show InChI InChI=1S/C21H12Cl2F4N2/c22-14-7-4-12(5-8-14)20-16-2-1-3-17(21(25,26)27)19(16)28-29(20)11-13-6-9-15(24)10-18(13)23/h1-10H,11H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	252	n/a	1.44E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26073 (2-benzyl-3-aryl-7-trifluoromethylindazole, 19 | 3-...) Show SMILES FC(F)(F)c1cccc2c(-c3ccc(Cl)cc3)n(Cc3ccccc3Cl)nc12 Show InChI InChI=1S/C21H13Cl2F3N2/c22-15-10-8-13(9-11-15)20-16-5-3-6-17(21(24,25)26)19(16)27-28(20)12-14-4-1-2-7-18(14)23/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	379	n/a	1.52E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair
Oxysterols receptor LXR-alpha [197-447] (Homo sapiens (Human))	BDBM26075 (2-benzyl-3-aryl-7-trifluoromethylindazole, 21 | 3-...) Show SMILES FC(F)(F)c1ccccc1Cn1nc2c(cccc2c1-c1ccc(Cl)cc1)C(F)(F)F Show InChI InChI=1S/C22H13ClF6N2/c23-15-10-8-13(9-11-15)20-16-5-3-7-18(22(27,28)29)19(16)30-31(20)12-14-4-1-2-6-17(14)21(24,25)26/h1-11H,12H2	PDB MMDB Reactome pathway UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	465	n/a	1.58E+4	n/a	n/a	n/a	n/a
Wyeth Research					Assay Description Binding reaction was initiated by adding a dilution series of test compound in tracer solution to LXR-coated flash plates. Each concentration of test...				J Med Chem 51: 7161-8 (2008) Article DOI: 10.1021/jm800799q BindingDB Entry DOI: 10.7270/Q2XW4H4G
					More data for this Ligand-Target Pair