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Compile Data Set for Download or QSAR

Found 1 hit of ec50 data for polymerid = 3417,3418,5020   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Trypanothione reductase


(Trypanosoma cruzi)		BDBM50313985
PNG
(8-methyl-8-azabicyclo[3.2.1]octan-3-one O-(4-chlor...)
Show SMILES [#6]-[#7]-1-[#6]-2-[#6]-[#6]-[#6]-1-[#6]\[#6](-[#6]-2)=[#7]\[#8]-[#6](-c1ccccc1)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H23ClN2O/c1-24-19-11-12-20(24)14-18(13-19)23-25-21(15-5-3-2-4-6-15)16-7-9-17(22)10-8-16/h2-10,19-21H,11-14H2,1H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 3.50E+4n/an/an/an/a



Institute of Medical Research

Curated by ChEMBL


Assay Description
Inhibition of Trypanosoma cruzi X10/1 recombinant trypanoythione reductase assessed as increase in absorbance at 410 nm due to the formation of TNB

Bioorg Med Chem Lett 20: 1816-8 (2010)


Article DOI: 10.1016/j.bmcl.2010.02.022
BindingDB Entry DOI: 10.7270/Q2J10396
More data for this
Ligand-Target Pair