Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Tyrosinase (Homo sapiens (Human)) | BDBM50293593 (4-(2-aminothiazol-4-yl)benzene-1,3-diol | CHEMBL54...) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | n/a | n/a | n/a | n/a | 51 | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Tyrosinase (Homo sapiens (Human)) | BDBM50322068 ((-)-N-Formylanonaine | CHEMBL1170090) | KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a |
Kaohsiung Medical University Curated by ChEMBL | Assay Description Inhibition of tyrosinase in human HEMn-MP assessed as reduction of melanin level after 2 days by spectrophotometric analysis | Bioorg Med Chem 18: 5241-7 (2010) Article DOI: 10.1016/j.bmc.2010.05.045 BindingDB Entry DOI: 10.7270/Q2JS9RFV | |||||||||||
More data for this Ligand-Target Pair |