Compile Data Set for Download or QSAR

Found 313 hits of ic50 data for polymerid = 50007112   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465164 (CHEMBL4288408) Show SMILES Cl.CN(C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C22H22F3NO2/c1-26(16-18-8-11-20-21(15-18)28-14-13-27-20)12-4-2-3-5-17-6-9-19(10-7-17)22(23,24)25/h2-11,15H,12-14,16H2,1H3/b4-2+,5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<0.100	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241355 (CHEMBL4075121) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C25H25NO/c1-26(19-21-11-14-25-24(18-21)15-17-27-25)16-5-6-20-9-12-23(13-10-20)22-7-3-2-4-8-22/h2-14,18H,15-17,19H2,1H3/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.330	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241304 (CHEMBL4077944) Show SMILES Cl.CN(C\C=C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C28H29NO/c1-29(22-24-15-18-27-12-8-20-30-28(27)21-24)19-7-3-4-9-23-13-16-26(17-14-23)25-10-5-2-6-11-25/h2-7,9-11,13-18,21H,8,12,19-20,22H2,1H3/b7-3+,9-4+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.360	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50177022 (CHEMBL3814424) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1cccc2ccoc12 Show InChI InChI=1S/C20H18F3NO.ClH/c1-24(14-17-6-2-5-16-11-13-25-19(16)17)12-3-4-15-7-9-18(10-8-15)20(21,22)23;/h2-11,13H,12,14H2,1H3;1H/b4-3+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247169 (CHEMBL4101749) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1cccc2cc[nH]c12 Show InChI InChI=1S/C25H24N2/c1-27(19-24-11-5-10-23-16-17-26-25(23)24)18-6-7-20-12-14-22(15-13-20)21-8-3-2-4-9-21/h2-17,26H,18-19H2,1H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465160 (CHEMBL4284707) Show SMILES Cl.CN(C\C=C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C24H24F3NO2/c1-28(18-20-10-13-22-23(17-20)30-16-15-29-22)14-6-4-2-3-5-7-19-8-11-21(12-9-19)24(25,26)27/h2-13,17H,14-16,18H2,1H3/b3-2+,6-4+,7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.400	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187723 (CHEMBL3827961) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCCCc3c2)cc1 Show InChI InChI=1S/C23H29NO.ClH/c1-24(16-6-7-19-11-14-23(25-2)15-12-19)18-20-10-13-21-8-4-3-5-9-22(21)17-20;/h6-7,10-15,17H,3-5,8-9,16,18H2,1-2H3;1H/b7-6+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.490	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187723 (CHEMBL3827961) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCCCc3c2)cc1 Show InChI InChI=1S/C23H29NO.ClH/c1-24(16-6-7-19-11-14-23(25-2)15-12-19)18-20-10-13-21-8-4-3-5-9-22(21)17-20;/h6-7,10-15,17H,3-5,8-9,16,18H2,1-2H3;1H/b7-6+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465164 (CHEMBL4288408) Show SMILES Cl.CN(C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C22H22F3NO2/c1-26(16-18-8-11-20-21(15-18)28-14-13-27-20)12-4-2-3-5-17-6-9-19(10-7-17)22(23,24)25/h2-11,15H,12-14,16H2,1H3/b4-2+,5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.600	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247168 (CHEMBL4086008) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1coc2ccccc12 Show InChI InChI=1S/C25H23NO/c1-26(18-23-19-27-25-12-6-5-11-24(23)25)17-7-8-20-13-15-22(16-14-20)21-9-3-2-4-10-21/h2-16,19H,17-18H2,1H3/b8-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465159 (CHEMBL4278050) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C20H20F3NO2/c1-24(14-16-6-9-18-19(13-16)26-12-11-25-18)10-2-3-15-4-7-17(8-5-15)20(21,22)23/h2-9,13H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in linezolid-resistant Staphylococcus aureus NRS271 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotome...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465160 (CHEMBL4284707) Show SMILES Cl.CN(C\C=C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C24H24F3NO2/c1-28(18-20-10-13-22-23(17-20)30-16-15-29-22)14-6-4-2-3-5-7-19-8-11-21(12-9-19)24(25,26)27/h2-13,17H,14-16,18H2,1H3/b3-2+,6-4+,7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465159 (CHEMBL4278050) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C20H20F3NO2/c1-24(14-16-6-9-18-19(13-16)26-12-11-25-18)10-2-3-15-4-7-17(8-5-15)20(21,22)23/h2-9,13H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in vancomycin-intermediate Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophoto...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241288 (CHEMBL4064940) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C26H27NO/c1-27(20-22-13-16-25-10-6-18-28-26(25)19-22)17-5-7-21-11-14-24(15-12-21)23-8-3-2-4-9-23/h2-5,7-9,11-16,19H,6,10,17-18,20H2,1H3/b7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187727 (CHEMBL3827744) Show SMILES Cl.CN(C\C=C\c1ccc(Br)cc1)Cc1ccc2CCCCc2c1 Show InChI InChI=1S/C21H24BrN.ClH/c1-23(14-4-5-17-9-12-21(22)13-10-17)16-18-8-11-19-6-2-3-7-20(19)15-18;/h4-5,8-13,15H,2-3,6-7,14,16H2,1H3;1H/b5-4+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formation after 48 hrs by spe...				J Med Chem 59: 4831-48 (2016) Article DOI: 10.1021/acs.jmedchem.6b00122 BindingDB Entry DOI: 10.7270/Q2FQ9ZKH
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465160 (CHEMBL4284707) Show SMILES Cl.CN(C\C=C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C24H24F3NO2/c1-28(18-20-10-13-22-23(17-20)30-16-15-29-22)14-6-4-2-3-5-7-19-8-11-21(12-9-19)24(25,26)27/h2-13,17H,14-16,18H2,1H3/b3-2+,6-4+,7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247168 (CHEMBL4086008) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1coc2ccccc12 Show InChI InChI=1S/C25H23NO/c1-26(18-23-19-27-25-12-6-5-11-24(23)25)17-7-8-20-13-15-22(16-14-20)21-9-3-2-4-10-21/h2-16,19H,17-18H2,1H3/b8-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.80	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman after 12 resistant development passages under 0.15% v/v H2O2 assessed as reduction in staphyloxant...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247168 (CHEMBL4086008) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1coc2ccccc12 Show InChI InChI=1S/C25H23NO/c1-26(18-23-19-27-25-12-6-5-11-24(23)25)17-7-8-20-13-15-22(16-14-20)21-9-3-2-4-10-21/h2-16,19H,17-18H2,1H3/b8-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187728 (CHEMBL3828585) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2CCCCc2c1 Show InChI InChI=1S/C22H24F3N.ClH/c1-26(16-18-8-11-19-6-2-3-7-20(19)15-18)14-4-5-17-9-12-21(13-10-17)22(23,24)25;/h4-5,8-13,15H,2-3,6-7,14,16H2,1H3;1H/b5-4+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187728 (CHEMBL3828585) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2CCCCc2c1 Show InChI InChI=1S/C22H24F3N.ClH/c1-26(16-18-8-11-19-6-2-3-7-20(19)15-18)14-4-5-17-9-12-21(13-10-17)22(23,24)25;/h4-5,8-13,15H,2-3,6-7,14,16H2,1H3;1H/b5-4+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formation after 48 hrs by spe...				J Med Chem 59: 4831-48 (2016) Article DOI: 10.1021/acs.jmedchem.6b00122 BindingDB Entry DOI: 10.7270/Q2FQ9ZKH
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247168 (CHEMBL4086008) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1coc2ccccc12 Show InChI InChI=1S/C25H23NO/c1-26(18-23-19-27-25-12-6-5-11-24(23)25)17-7-8-20-13-15-22(16-14-20)21-9-3-2-4-10-21/h2-16,19H,17-18H2,1H3/b8-7+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241368 (CHEMBL4096875) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C20H20F3NO/c1-24(14-16-6-9-19-17(13-16)10-12-25-19)11-2-3-15-4-7-18(8-5-15)20(21,22)23/h2-9,13H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of [3H]baclofen binding to rat gamma-aminobutyric acid type B receptor.				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241368 (CHEMBL4096875) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C20H20F3NO/c1-24(14-16-6-9-19-17(13-16)10-12-25-19)11-2-3-15-4-7-18(8-5-15)20(21,22)23/h2-9,13H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Mu50 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241355 (CHEMBL4075121) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C25H25NO/c1-26(19-21-11-14-25-24(18-21)15-17-27-25)16-5-6-20-9-12-23(13-10-20)22-7-3-2-4-8-22/h2-14,18H,15-17,19H2,1H3/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465164 (CHEMBL4288408) Show SMILES Cl.CN(C\C=C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C22H22F3NO2/c1-26(16-18-8-11-20-21(15-18)28-14-13-27-20)12-4-2-3-5-17-6-9-19(10-7-17)22(23,24)25/h2-11,15H,12-14,16H2,1H3/b4-2+,5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247338 (CHEMBL4062732) Show SMILES Cl.CN(C\C=C\c1ccc(Br)cc1)Cc1coc2ccccc12 Show InChI InChI=1S/C19H18BrNO/c1-21(12-4-5-15-8-10-17(20)11-9-15)13-16-14-22-19-7-3-2-6-18(16)19/h2-11,14H,12-13H2,1H3/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247169 (CHEMBL4101749) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1cccc2cc[nH]c12 Show InChI InChI=1S/C25H24N2/c1-27(19-24-11-5-10-23-16-17-26-25(23)24)18-6-7-20-12-14-22(15-13-20)21-8-3-2-4-9-21/h2-17,26H,18-19H2,1H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman after 12 resistant development passages under 0.15% v/v H2O2 assessed as reduction in staphyloxant...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465159 (CHEMBL4278050) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C20H20F3NO2/c1-24(14-16-6-9-18-19(13-16)26-12-11-25-18)10-2-3-15-4-7-17(8-5-15)20(21,22)23/h2-9,13H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	2.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241304 (CHEMBL4077944) Show SMILES Cl.CN(C\C=C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C28H29NO/c1-29(22-24-15-18-27-12-8-20-30-28(27)21-24)19-7-3-4-9-23-13-16-26(17-14-23)25-10-5-2-6-11-25/h2-7,9-11,13-18,21H,8,12,19-20,22H2,1H3/b7-3+,9-4+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465165 (CHEMBL4288709) Show SMILES Cl.CN(C\C=C\c1ccc(C)cc1)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C20H23NO2/c1-16-5-7-17(8-6-16)4-3-11-21(2)15-18-9-10-19-20(14-18)23-13-12-22-19/h3-10,14H,11-13,15H2,1-2H3/b4-3+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247169 (CHEMBL4101749) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1cccc2cc[nH]c12 Show InChI InChI=1S/C25H24N2/c1-27(19-24-11-5-10-23-16-17-26-25(23)24)18-6-7-20-12-14-22(15-13-20)21-8-3-2-4-9-21/h2-17,26H,18-19H2,1H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.30	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241288 (CHEMBL4064940) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C26H27NO/c1-27(20-22-13-16-25-10-6-18-28-26(25)19-22)17-5-7-21-11-14-24(15-12-21)23-8-3-2-4-9-23/h2-5,7-9,11-16,19H,6,10,17-18,20H2,1H3/b7-5+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247169 (CHEMBL4101749) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1cccc2cc[nH]c12 Show InChI InChI=1S/C25H24N2/c1-27(19-24-11-5-10-23-16-17-26-25(23)24)18-6-7-20-12-14-22(15-13-20)21-8-3-2-4-9-21/h2-17,26H,18-19H2,1H3/b7-6+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187723 (CHEMBL3827961) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCCCc3c2)cc1 Show InChI InChI=1S/C23H29NO.ClH/c1-24(16-6-7-19-11-14-23(25-2)15-12-19)18-20-10-13-21-8-4-3-5-9-22(21)17-20;/h6-7,10-15,17H,3-5,8-9,16,18H2,1-2H3;1H/b7-6+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50465177 (CHEMBL4290446) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)-c1ccccc1)Cc1ccc2OCCOc2c1 Show InChI InChI=1S/C25H25NO2/c1-26(19-21-11-14-24-25(18-21)28-17-16-27-24)15-5-6-20-9-12-23(13-10-20)22-7-3-2-4-8-22/h2-14,18H,15-17,19H2,1H3/b6-5+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187723 (CHEMBL3827961) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCCCc3c2)cc1 Show InChI InChI=1S/C23H29NO.ClH/c1-24(16-6-7-19-11-14-23(25-2)15-12-19)18-20-10-13-21-8-4-3-5-9-22(21)17-20;/h6-7,10-15,17H,3-5,8-9,16,18H2,1-2H3;1H/b7-6+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				ACS Med Chem Lett 9: 233-237 (2018) Article DOI: 10.1021/acsmedchemlett.7b00501 BindingDB Entry DOI: 10.7270/Q2V127GN
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50187723 (CHEMBL3827961) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCCCc3c2)cc1 Show InChI InChI=1S/C23H29NO.ClH/c1-24(16-6-7-19-11-14-23(25-2)15-12-19)18-20-10-13-21-8-4-3-5-9-22(21)17-20;/h6-7,10-15,17H,3-5,8-9,16,18H2,1-2H3;1H/b7-6+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.10	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of diapophytoene desaturase in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin pigment formation after 48 hrs by spe...				J Med Chem 59: 4831-48 (2016) Article DOI: 10.1021/acs.jmedchem.6b00122 BindingDB Entry DOI: 10.7270/Q2FQ9ZKH
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241314 (CHEMBL4072535) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)F)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C21H23F2NO/c1-24(12-2-4-16-6-10-19(11-7-16)21(22)23)15-17-8-9-18-5-3-13-25-20(18)14-17/h2,4,6-11,14,21H,3,5,12-13,15H2,1H3/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241334 (CHEMBL4094016) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C21H22F3NO/c1-25(15-17-6-9-18-5-3-13-26-20(18)14-17)12-2-4-16-7-10-19(11-8-16)21(22,23)24/h2,4,6-11,14H,3,5,12-13,15H2,1H3/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.60	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241421 (CHEMBL4065307) Show SMILES Cl.CN(C\C=C\c1ccc(cc1F)C(F)(F)F)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C21H21F4NO/c1-26(14-15-6-7-17-5-3-11-27-20(17)12-15)10-2-4-16-8-9-18(13-19(16)22)21(23,24)25/h2,4,6-9,12-13H,3,5,10-11,14H2,1H3/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.70	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241273 (CHEMBL4069757) Show SMILES Cl.CN(C\C=C\c1ccc(Br)cc1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C20H22BrNO/c1-22(12-2-4-16-7-10-19(21)11-8-16)15-17-6-9-18-5-3-13-23-20(18)14-17/h2,4,6-11,14H,3,5,12-13,15H2,1H3/b4-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	4.80	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247173 (CHEMBL4100870) Show SMILES Cl.CN(C\C=C\c1ccc(Cl)cc1)Cc1coc2ccccc12 Show InChI InChI=1S/C19H18ClNO/c1-21(12-4-5-15-8-10-17(20)11-9-15)13-16-14-22-19-7-3-2-6-18(16)19/h2-11,14H,12-13H2,1H3/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241278 (CHEMBL4088312) Show SMILES Cl.CN(C\C=C\c1ccc2ccccc2c1)Cc1ccc2CCCOc2c1 Show InChI InChI=1S/C24H25NO/c1-25(18-20-11-13-22-9-5-15-26-24(22)17-20)14-4-6-19-10-12-21-7-2-3-8-23(21)16-19/h2-4,6-8,10-13,16-17H,5,9,14-15,18H2,1H3/b6-4+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241397 (CHEMBL4078841) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)F)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C20H21F2NO/c1-23(14-16-6-9-19-18(13-16)10-12-24-19)11-2-3-15-4-7-17(8-5-15)20(21)22/h2-9,13,20H,10-12,14H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL MMDB PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241248 (CHEMBL4102178) Show SMILES Cl.CN(C\C=C\c1ccc2ccccc2c1)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C23H23NO/c1-24(17-19-9-11-23-22(16-19)12-14-25-23)13-4-5-18-8-10-20-6-2-3-7-21(20)15-18/h2-11,15-16H,12-14,17H2,1H3/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Binding affinity for human placental microsome cytochrome P450 19A1 with 1 uM [1-beta-3H]-androstenedione				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50177022 (CHEMBL3814424) Show SMILES Cl.CN(C\C=C\c1ccc(cc1)C(F)(F)F)Cc1cccc2ccoc12 Show InChI InChI=1S/C20H18F3NO.ClH/c1-24(14-17-6-2-5-16-11-13-25-19(16)17)12-3-4-15-7-9-18(10-8-15)20(21,22)23;/h2-11,13H,12,14H2,1H3;1H/b4-3+;	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in methicillin-resistant Staphylococcus aureus LAC USA300 assessed as reduction in staphyloxanthin levels after 48 hrs by spectrop...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241401 (CHEMBL4102707) Show SMILES Cl.CN(C\C=C\c1ccc(cc1F)C(F)(F)F)Cc1ccc2OCCc2c1 Show InChI InChI=1S/C20H19F4NO/c1-25(13-14-4-7-19-16(11-14)8-10-26-19)9-2-3-15-5-6-17(12-18(15)21)20(22,23)24/h2-7,11-12H,8-10,13H2,1H3/b3-2+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.80	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241392 (CHEMBL4103161) Show SMILES Cl.COc1ccc(\C=C\CN(C)Cc2ccc3CCCOc3c2)c(F)c1 Show InChI InChI=1S/C21H24FNO2/c1-23(11-3-5-17-9-10-19(24-2)14-20(17)22)15-16-7-8-18-6-4-12-25-21(18)13-16/h3,5,7-10,13-14H,4,6,11-12,15H2,1-2H3/b5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50241285 (CHEMBL4084875) Show SMILES Cl.COC(=O)c1ccc(\C=C\CN(C)Cc2ccc3CCCOc3c2)cc1 Show InChI InChI=1S/C22H25NO3/c1-23(16-18-9-10-19-6-4-14-26-21(19)15-18)13-3-5-17-7-11-20(12-8-17)22(24)25-2/h3,5,7-12,15H,4,6,13-14,16H2,1-2H3/b5-3+	UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.90	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric analysis				J Med Chem 60: 8145-8159 (2017) Article DOI: 10.1021/acs.jmedchem.7b00949 BindingDB Entry DOI: 10.7270/Q2445PNX
					More data for this Ligand-Target Pair
4,4'-diapophytoene desaturase (4,4'-diaponeurosporene-forming) (Staphylococcus aureus (strain Newman))	BDBM50247237 (CHEMBL4087908) Show SMILES Cl.CN(C\C=C\c1ccc(Cl)cc1Cl)Cc1coc2ccccc12 Show InChI InChI=1S/C19H17Cl2NO/c1-22(10-4-5-14-8-9-16(20)11-18(14)21)12-15-13-23-19-7-3-2-6-17(15)19/h2-9,11,13H,10,12H2,1H3/b5-4+	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20	n/a	n/a	n/a	n/a	n/a	n/a
East China University of Science and Technology Curated by ChEMBL					Assay Description Inhibition of CrtN in Staphylococcus aureus Newman assessed as reduction in staphyloxanthin levels after 48 hrs by spectrophotometric method-based pi...				J Med Chem 61: 224-250 (2018) Article DOI: 10.1021/acs.jmedchem.7b01300 BindingDB Entry DOI: 10.7270/Q289189X
					More data for this Ligand-Target Pair

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