Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Thymidine phosphorylase (Mus musculus) | BDBM50452155 (3''-FFdUrd | CHEMBL1098358) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | PubMed | 1.70E+6 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Compound was evaluated in vitro for non-competitive inhibition of cleavage of Thymidine (dThd) phosphorylase isolated from Lewis lung carcinoma. | J Med Chem 27: 11-4 (1984) BindingDB Entry DOI: 10.7270/Q2J67FXS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Thymidine phosphorylase (Mus musculus) | BDBM50134397 (5-Methyl-1H-pyrimidine-2,4-dione | CHEMBL993 | THY...) | Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE KEGG MMDB PC cid PC sid PDB UniChem Patents Similars | PubMed | 3.47E+8 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
University of Manchester Curated by ChEMBL | Assay Description Inhibitory activity against mouse liver thymidine phosphorylase at 0.15 mM thymidine substrate | Bioorg Med Chem Lett 13: 3705-9 (2003) BindingDB Entry DOI: 10.7270/Q2SQ90ZZ | |||||||||||
More data for this Ligand-Target Pair |