Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Disintegrin and metalloproteinase domain-containing protein 12 (Homo sapiens (Human)) | BDBM50062351 ((R)-N*4*-Hydroxy-N*1*-[(S)-2-(1H-indol-3-yl)-1-met...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents Similars | Article PubMed | n/a | n/a | 5.93 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Life Science and National Research Laboratory of Proteolysis Curated by ChEMBL | Assay Description Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay | Bioorg Med Chem Lett 14: 6071-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.082 BindingDB Entry DOI: 10.7270/Q29Z94DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 12 (Homo sapiens (Human)) | BDBM50156477 (CHEMBL366034 | {3-(3-Bromo-phenyl)-2-[(furan-2-car...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 16.7 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Life Science and National Research Laboratory of Proteolysis Curated by ChEMBL | Assay Description Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay | Bioorg Med Chem Lett 14: 6071-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.082 BindingDB Entry DOI: 10.7270/Q29Z94DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 12 (Homo sapiens (Human)) | BDBM50156475 (2-[2-[(5-Bromo-furan-2-carbonyl)-amino]-3-(4-bromo...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 24.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Life Science and National Research Laboratory of Proteolysis Curated by ChEMBL | Assay Description Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay | Bioorg Med Chem Lett 14: 6071-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.082 BindingDB Entry DOI: 10.7270/Q29Z94DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 12 (Homo sapiens (Human)) | BDBM50156476 (2-[2-Benzoylamino-3-(2-fluoro-phenyl)-acryloylamin...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem | Article PubMed | n/a | n/a | 40.5 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Life Science and National Research Laboratory of Proteolysis Curated by ChEMBL | Assay Description Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay | Bioorg Med Chem Lett 14: 6071-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.082 BindingDB Entry DOI: 10.7270/Q29Z94DH | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Disintegrin and metalloproteinase domain-containing protein 12 (Homo sapiens (Human)) | BDBM50156478 (2-{2-[(Furan-2-carbonyl)-amino]-3-furan-2-yl-acryl...) | NCI pathway Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 42.3 | n/a | n/a | n/a | n/a | n/a | n/a |
Department of Life Science and National Research Laboratory of Proteolysis Curated by ChEMBL | Assay Description Inhibition of A disintegrin and metalloproteinase domain 12 (ADAM12) binding in cell based assay | Bioorg Med Chem Lett 14: 6071-4 (2004) Article DOI: 10.1016/j.bmcl.2004.09.082 BindingDB Entry DOI: 10.7270/Q29Z94DH | |||||||||||
More data for this Ligand-Target Pair |