Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Trypanothione reductase (Crithidia fasciculata) | BDBM50240622 (3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50240622 (3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pontificia Universidad Catolica del Peru Curated by ChEMBL | Assay Description Inhibition of Crithidia fasciculata free trypanothione reductase | Bioorg Med Chem 16: 6689-95 (2008) Article DOI: 10.1016/j.bmc.2008.05.074 BindingDB Entry DOI: 10.7270/Q2F18ZHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50240622 (3-(3,4-Dihydroxy-phenyl)-N-[3-(4-{3-[3-(3,4-dihydr...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | 1.30E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Pontificia Universidad Catolica del Peru Curated by ChEMBL | Assay Description Inhibition of Crithidia fasciculata trypanothione reductase-substrate complex | Bioorg Med Chem 16: 6689-95 (2008) Article DOI: 10.1016/j.bmc.2008.05.074 BindingDB Entry DOI: 10.7270/Q2F18ZHB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50615384 (CHEMBL80264) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | UniChem | 8.50E+4 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a | |
TBA | Citation and Details | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50242977 (CHEMBL500862 | Cepharanthine | cepharantine) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.50E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85440 (Lindoldhamine (R,R)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.70E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85441 (Daphnoline (R,S)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.00E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50241641 ((+)-Homoaromoline | CHEMBL509855 | Homoaromoline |...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.50E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85442 (Gyrocarpine (S,R)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 5.80E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM50292467 (Antioquine | Antioquine (S,R) | CHEMBL446564 | CHE...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM41947 ((-)-BEBEERINE | MLS000069827 | SMR000058852 | bebe...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 6.00E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85443 (Limacine (R,R)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 9.00E+4 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85444 (CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 1.22E+5 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85444 (CHEMBL506025 | Isotetrandrine (R,S) | Pheanthine (...) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase CHEMBL MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 2.35E+5 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Trypanothione reductase (Crithidia fasciculata) | BDBM85446 (Cycleanine (R,R)) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | Purchase MCE KEGG PC cid PC sid UniChem Similars | Article PubMed | n/a | n/a | 3.03E+5 | n/a | n/a | n/a | n/a | 7.8 | 25 |
ORSTOM | Assay Description Crithidia fasciculata trypanothione reductase (cfTR) was purifed from E.coli using the expression system. The activity of the cfTR was observed from... | J Enzym Inhib 13: 1-9 (1998) Article DOI: 10.3109/14756369809035823 BindingDB Entry DOI: 10.7270/Q29Z93FJ | |||||||||||
More data for this Ligand-Target Pair |