Compile Data Set for Download or QSAR

Found 7 hits Enz. Inhib. hit(s) with Target = 'Cytohesin-2'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cytohesin-2 (Homo sapiens (Human))	BDBM50441977 (CHEMBL2440208) Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	n/a	n/a	n/a	5.00E+5	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Binding affinity to human Arno Sec7 domain immobilized on CAP sensor chip after 15 mins by 1H 1D-NMR-700 MHz spectra analysis				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytohesin-2 (Homo sapiens (Human))	BDBM50441975 (CHEMBL2440216) Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C14H14N2O5S/c1-9-7-12(17)8-10(2)14(9)15-22(20,21)13-5-3-11(4-6-13)16(18)19/h3-8,15,17H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.40E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair
Cytohesin-2 (Homo sapiens (Human))	BDBM50441972 (CHEMBL2440207) Show SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)Nc1ccc(O)cc1C Show InChI InChI=1S/C16H19NO3S/c1-10-7-12(3)16(13(4)8-10)21(19,20)17-15-6-5-14(18)9-11(15)2/h5-9,17-18H,1-4H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9.80E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair
Cytohesin-2 (Homo sapiens (Human))	BDBM50441973 (CHEMBL2440218) Show SMILES COc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C Show InChI InChI=1S/C15H17NO4S/c1-10-8-12(17)9-11(2)15(10)16-21(18,19)14-6-4-13(20-3)5-7-14/h4-9,16-17H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	1.61E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytohesin-2 (Homo sapiens (Human))	BDBM50441976 (CHEMBL2440213) Show SMILES Cc1ccc(cc1)S(=O)(=O)Nc1c(C)cc(O)cc1C Show InChI InChI=1S/C15H17NO3S/c1-10-4-6-14(7-5-10)20(18,19)16-15-11(2)8-13(17)9-12(15)3/h4-9,16-17H,1-3H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.91E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair
Cytohesin-2 (Homo sapiens (Human))	BDBM50441977 (CHEMBL2440208) Show SMILES Cc1cc(O)cc(C)c1NS(=O)(=O)c1ccccc1 Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(16)9-11(2)14(10)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Similars	PDB Article PubMed	3.72E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair				3D Structure (crystal)
Cytohesin-2 (Homo sapiens (Human))	BDBM50441974 (CHEMBL236358) Show SMILES Cc1cc(NS(=O)(=O)c2ccccc2)cc(C)c1O Show InChI InChI=1S/C14H15NO3S/c1-10-8-12(9-11(2)14(10)16)15-19(17,18)13-6-4-3-5-7-13/h3-9,15-16H,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.12E+6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
UMR 5247 Curated by ChEMBL					Assay Description Inhibition of human Arno Sec7 domain-mediated nucleotide exchange in delta17 Arf1 (17 to 181) by BODIPY-GTP based time resolved fluorescence assay				J Med Chem 56: 8497-511 (2013) Article DOI: 10.1021/jm4009357 BindingDB Entry DOI: 10.7270/Q2251KMF
					More data for this Ligand-Target Pair