Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Leucine--tRNA ligase (Candida albicans (Ascomycetes)) | BDBM163674 (AN2690-AMP) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | n/a | 700 | n/a | n/a | n/a | 8.0 | 25 |
Grenoble Outstation and Unit of Virus Host-Cell Interactions, UJF-EMBL-CNRS, UMI 3265 | Assay Description ITC was performed using LeuRS CP1 domain wild-type, K510E mutant, or K510A mutant against AN2690-AMP at 25 °C by an ITC200 system (MicroCal, GE Healt... | ACS Chem Biol 10: 2277-85 (2015) Article DOI: 10.1021/acschembio.5b00291 BindingDB Entry DOI: 10.7270/Q29Z93N7 | |||||||||||
More data for this Ligand-Target Pair |