Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172453 (US9090625, 5 | US9260450, 5 | US9938289, 5) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 12.9 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172455 (US9090625, 7 | US9260450, 7 | US9938289, 7) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 6.65 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172449 (US9090625, 1 | US9260450, 1 | US9938289, 1) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 23.4 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172458 (US9090625, 13 | US9260450, 13 | US9938289, 13) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 18.9 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172452 (US9090625, 4 | US9260450, 4 | US9938289, 4) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | MCE PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.33 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172454 (US9090625, 6 | US9260450, 6 | US9938289, 6) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 35.2 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172457 (US9090625, 12 | US9260450, 12 | US9938289, 12) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 7.94 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172451 (US9090625, 3 | US9260450, 3 | US9938289, 3) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 108 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
TGF-beta receptor type-1 (Homo sapiens (Human)) | BDBM172450 (US9090625, 2 | US9260450, 2 | US9938289, 2) | PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 94.1 | n/a | n/a | n/a | n/a | n/a | n/a |
THESAN PHARMACEUTICALS, INC. US Patent | Assay Description Pharmacol 2002, 62 58-62) The compounds named in the specified Examples were tested as follows for inhibition of ALK-5 autophosphorylation activity a... | US Patent US9090625 (2015) BindingDB Entry DOI: 10.7270/Q2BG2MRM | |||||||||||
More data for this Ligand-Target Pair |