Affinity Data by Patent

Patent code US8481743

Found 8 hits of Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Mu-type opioid receptor (Homo sapiens (Human))	BDBM98008 (US8481743, 4) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	19.2	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM98007 (US8481743, 3) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	36.1	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM98009 (US8481743, 1) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	82.8	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Mu-type opioid receptor (Homo sapiens (Human))	BDBM98006 (US8481743, 2) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	331	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM98006 (US8481743, 2) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM98009 (US8481743, 1) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM98008 (US8481743, 4) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair
Nociceptin receptor (Homo sapiens (Human))	BDBM98007 (US8481743, 3) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	>2.00E+4	n/a	n/a	n/a	n/a	n/a	n/a	7.4	n/a
Purdue Pharma L.P. US Patent					Assay Description Radioligand binding assay (for screening and dose-displacement) using u-opioid and ORL-1 receptor.				US Patent US8481743 (2013) BindingDB Entry DOI: 10.7270/Q2BK19Z7
Purdue Pharma L.P. US Patent					More data for this Ligand-Target Pair

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* indicates data uncertainty>20%