Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM119676 (US8680119, 15) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.0820 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1... | US Patent US8680119 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM119679 (US8680119, 68) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 0.510 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1... | US Patent US8680119 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM119677 (US8680119, 52) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1... | US Patent US8680119 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MB0 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 2A (Homo sapiens (Human)) | BDBM119678 (US8680119, 50) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Similars | US Patent | n/a | n/a | 52 | n/a | n/a | n/a | n/a | 7.4 | n/a |
Arena Pharmaceuticals, Inc. US Patent | Assay Description Radioligand binding assays for human 5-HT2A receptor was conducted using the 5-HT2 agonist [125I]DOI as radioligand. To define nonspecific binding, 1... | US Patent US8680119 (2014) BindingDB Entry DOI: 10.7270/Q2RV0MB0 | |||||||||||
More data for this Ligand-Target Pair |