BindingDB logo
myBDB logout

Patent code US9409892

Compile Data Set for Download or QSAR

Found 368 hits of Enzyme Inhibition Constant Data   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240913
PNG
(US9409892, 8)
Show SMILES CC(C)(CCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H22N2O5/c1-22(2,21(27)28)10-11-23-20(26)18-19(25)17-9-8-16(12-14(17)13-24-18)29-15-6-4-3-5-7-15/h3-9,12-13,25H,10-11H2,1-2H3,(H,23,26)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.16E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240916
PNG
(US9409892, 11)
Show SMILES CC(CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H17N3O5/c1-12(9-18(25)26)23-21(28)19-20(27)15-8-7-14(10-16(15)17(11-22)24-19)29-13-5-3-2-4-6-13/h2-8,10,12,27H,9H2,1H3,(H,23,28)(H,25,26)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.37E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240918
PNG
(US9409892, 13)
Show SMILES OC(=O)C1(CNC(=O)c2ncc3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C22H20N2O5/c25-19-17-8-7-16(29-15-5-2-1-3-6-15)11-14(17)12-23-18(19)20(26)24-13-22(21(27)28)9-4-10-22/h1-3,5-8,11-12,25H,4,9-10,13H2,(H,24,26)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.51E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240919
PNG
(US9409892, 14)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C23H19N3O5/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 310n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240924
PNG
(US9409892, 19)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCCC1
Show InChI InChI=1S/C24H21N3O5/c25-13-19-18-12-16(32-15-6-2-1-3-7-15)8-9-17(18)21(28)20(27-19)22(29)26-14-24(23(30)31)10-4-5-11-24/h1-3,6-9,12,28H,4-5,10-11,14H2,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.73E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240925
PNG
(US9409892, 20)
Show SMILES COc1ccc(Oc2ccc3c(O)c(nc(C#N)c3c2)C(=O)NCC(C)(C)C(O)=O)cc1
Show InChI InChI=1S/C23H21N3O6/c1-23(2,22(29)30)12-25-21(28)19-20(27)16-9-8-15(10-17(16)18(11-24)26-19)32-14-6-4-13(31-3)5-7-14/h4-10,27H,12H2,1-3H3,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 350n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240927
PNG
(US9409892, 22)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3c(F)cccc3F)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H17F2N3O5/c1-22(2,21(30)31)10-26-20(29)17-18(28)12-7-6-11(8-13(12)16(9-25)27-17)32-19-14(23)4-3-5-15(19)24/h3-8,28H,10H2,1-2H3,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 930n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240929
PNG
(US9409892, 24)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(Oc3cccnc3)ccc2c1O
Show InChI InChI=1S/C18H15N3O5/c22-15(23)5-7-20-18(25)16-17(24)14-4-3-12(8-11(14)9-21-16)26-13-2-1-6-19-10-13/h1-4,6,8-10,24H,5,7H2,(H,20,25)(H,22,23)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.31E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240937
PNG
(US9409892, 32)
Show SMILES OC(=O)[C@@H]1CCCCC1NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O |r|
Show InChI InChI=1S/C24H21N3O5/c25-13-20-18-12-15(32-14-6-2-1-3-7-14)10-11-16(18)22(28)21(26-20)23(29)27-19-9-5-4-8-17(19)24(30)31/h1-3,6-7,10-12,17,19,28H,4-5,8-9H2,(H,27,29)(H,30,31)/t17-,19?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.80E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240938
PNG
(US9409892, 33)
Show SMILES OC(=O)[C@@H]1CCCC1NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O |r|
Show InChI InChI=1S/C23H19N3O5/c24-12-19-17-11-14(31-13-5-2-1-3-6-13)9-10-15(17)21(27)20(25-19)22(28)26-18-8-4-7-16(18)23(29)30/h1-3,5-6,9-11,16,18,27H,4,7-8H2,(H,26,28)(H,29,30)/t16-,18?/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.69E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241051
PNG
(US9409892, 146)
Show SMILES CC(C)(CNC(=O)c1ncc2cc(Cc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H22N2O4/c1-22(2,21(27)28)13-24-20(26)18-19(25)17-9-8-15(11-16(17)12-23-18)10-14-6-4-3-5-7-14/h3-9,11-12,25H,10,13H2,1-2H3,(H,24,26)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.37E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241056
PNG
(US9409892, 151)
Show SMILES Cn1nc(cc1-c1nc(C(=O)NCC(C)(C)C(O)=O)c(O)c2ccc(Oc3ccccc3)cc12)C(F)(F)F
Show InChI InChI=1S/C26H23F3N4O5/c1-25(2,24(36)37)13-30-23(35)21-22(34)16-10-9-15(38-14-7-5-4-6-8-14)11-17(16)20(31-21)18-12-19(26(27,28)29)32-33(18)3/h4-12,34H,13H2,1-3H3,(H,30,35)(H,36,37)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.28E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241059
PNG
(US9409892, 154)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Sc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C23H19N3O4S/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 110n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241075
PNG
(US9409892, 170)
Show SMILES OC(=O)C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1ccccc1F |r|
Show InChI InChI=1S/C26H18FN3O5/c27-20-9-5-4-8-18(20)21(13-23(31)32)30-26(34)24-25(33)17-11-10-16(12-19(17)22(14-28)29-24)35-15-6-2-1-3-7-15/h1-12,21,33H,13H2,(H,30,34)(H,31,32)/t21-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.76E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241076
PNG
(US9409892, 171)
Show SMILES Cc1ccccc1[C@H](CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O |r|
Show InChI InChI=1S/C27H21N3O5/c1-16-7-5-6-10-19(16)22(14-24(31)32)30-27(34)25-26(33)20-12-11-18(13-21(20)23(15-28)29-25)35-17-8-3-2-4-9-17/h2-13,22,33H,14H2,1H3,(H,30,34)(H,31,32)/t22-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.26E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241080
PNG
(US9409892, 175)
Show SMILES OC(=O)C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1cccnc1 |r|
Show InChI InChI=1S/C25H18N4O5/c26-13-21-19-11-17(34-16-6-2-1-3-7-16)8-9-18(19)24(32)23(28-21)25(33)29-20(12-22(30)31)15-5-4-10-27-14-15/h1-11,14,20,32H,12H2,(H,29,33)(H,30,31)/t20-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.51E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241083
PNG
(US9409892, 178)
Show SMILES OC(=O)C(CNC(=O)c1nc(C#N)c2cc(Oc3cccnc3)ccc2c1O)C1CC1
Show InChI InChI=1S/C22H18N4O5/c23-9-18-16-8-13(31-14-2-1-7-24-10-14)5-6-15(16)20(27)19(26-18)21(28)25-11-17(22(29)30)12-3-4-12/h1-2,5-8,10,12,17,27H,3-4,11H2,(H,25,28)(H,29,30)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.65E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241085
PNG
(US9409892, 180)
Show SMILES OC(=O)C(CNC(=O)c1nc(C#N)c2cc(Oc3c(F)cccc3F)ccc2c1O)C1CC1
Show InChI InChI=1S/C23H17F2N3O5/c24-16-2-1-3-17(25)21(16)33-12-6-7-13-14(8-12)18(9-26)28-19(20(13)29)22(30)27-10-15(23(31)32)11-4-5-11/h1-3,6-8,11,15,29H,4-5,10H2,(H,27,30)(H,31,32)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.57E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240906
PNG
(US9409892, 1)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C19H16N2O5/c22-16(23)8-9-20-19(25)17-18(24)15-7-6-14(10-12(15)11-21-17)26-13-4-2-1-3-5-13/h1-7,10-11,24H,8-9H2,(H,20,25)(H,22,23)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.04E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240910
PNG
(US9409892, 5)
Show SMILES OC(=O)CCCCNC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H20N2O5/c24-18(25)8-4-5-11-22-21(27)19-20(26)17-10-9-16(12-14(17)13-23-19)28-15-6-2-1-3-7-15/h1-3,6-7,9-10,12-13,26H,4-5,8,11H2,(H,22,27)(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.17E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240911
PNG
(US9409892, 6)
Show SMILES CC(C)(CC(O)=O)NC(=O)c1ncc2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H20N2O5/c1-21(2,11-17(24)25)23-20(27)18-19(26)16-9-8-15(10-13(16)12-22-18)28-14-6-4-3-5-7-14/h3-10,12,26H,11H2,1-2H3,(H,23,27)(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.92E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240918
PNG
(US9409892, 13)
Show SMILES OC(=O)C1(CNC(=O)c2ncc3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C22H20N2O5/c25-19-17-8-7-16(29-15-5-2-1-3-6-15)11-14(17)12-23-18(19)20(26)24-13-22(21(27)28)9-4-10-22/h1-3,5-8,11-12,25H,4,9-10,13H2,(H,24,26)(H,27,28)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.08E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240919
PNG
(US9409892, 14)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(Oc4ccccc4)ccc3c2O)CCC1
Show InChI InChI=1S/C23H19N3O5/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h1-3,5-8,11,27H,4,9-10,13H2,(H,25,28)(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.52E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240967
PNG
(US9409892, 62)
Show SMILES CCc1ccccc1Oc1ccc2c(O)c(nc(C#N)c2c1)C(=O)NCC(C)(C)C(O)=O
Show InChI InChI=1S/C24H23N3O5/c1-4-14-7-5-6-8-19(14)32-15-9-10-16-17(11-15)18(12-25)27-20(21(16)28)22(29)26-13-24(2,3)23(30)31/h5-11,28H,4,13H2,1-3H3,(H,26,29)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 480n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240977
PNG
(US9409892, 72)
Show SMILES C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@@H](C)C(O)=O |r|
Show InChI InChI=1S/C22H19N3O5/c1-12(22(28)29)13(2)24-21(27)19-20(26)16-9-8-15(10-17(16)18(11-23)25-19)30-14-6-4-3-5-7-14/h3-10,12-13,26H,1-2H3,(H,24,27)(H,28,29)/t12-,13+/m1/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.18E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240983
PNG
(US9409892, 78)
Show SMILES C[C@@H](CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O |r|
Show InChI InChI=1S/C21H17N3O5/c1-12(9-18(25)26)23-21(28)19-20(27)15-8-7-14(10-16(15)17(11-22)24-19)29-13-5-3-2-4-6-13/h2-8,10,12,27H,9H2,1H3,(H,23,28)(H,25,26)/t12-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.27E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240991
PNG
(US9409892, 86)
Show SMILES N[C@@H](CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O |r|
Show InChI InChI=1S/C20H16N4O5/c21-9-16-14-8-12(29-11-4-2-1-3-5-11)6-7-13(14)18(25)17(24-16)19(26)23-10-15(22)20(27)28/h1-8,15,25H,10,22H2,(H,23,26)(H,27,28)/t15-/m0/s1
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.51E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240994
PNG
(US9409892, 89)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)CC(O)=O
Show InChI InChI=1S/C23H21N3O5/c1-23(2,11-19(27)28)13-25-22(30)20-21(29)16-9-8-15(10-17(16)18(12-24)26-20)31-14-6-4-3-5-7-14/h3-10,29H,11,13H2,1-2H3,(H,25,30)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.86E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM240996
PNG
(US9409892, 91)
Show SMILES OC(=O)CC(NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)c1ccccc1
Show InChI InChI=1S/C26H19N3O5/c27-15-22-20-13-18(34-17-9-5-2-6-10-17)11-12-19(20)25(32)24(28-22)26(33)29-21(14-23(30)31)16-7-3-1-4-8-16/h1-13,21,32H,14H2,(H,29,33)(H,30,31)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.91E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241026
PNG
(US9409892, 121)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Sc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H19N3O4S/c1-22(2,21(28)29)12-24-20(27)18-19(26)15-9-8-14(10-16(15)17(11-23)25-18)30-13-6-4-3-5-7-13/h3-10,26H,12H2,1-2H3,(H,24,27)(H,28,29)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 840n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Prolyl hydroxylase EGLN2


(Homo sapiens (Human))		BDBM241030
PNG
(US9409892, 125)
Show SMILES COc1ccc(CNc2ccc3c(O)c(ncc3c2)C(=O)NCCCCC(O)=O)cc1
Show InChI InChI=1S/C23H25N3O5/c1-31-18-8-5-15(6-9-18)13-25-17-7-10-19-16(12-17)14-26-21(22(19)29)23(30)24-11-3-2-4-20(27)28/h5-10,12,14,25,29H,2-4,11,13H2,1H3,(H,24,30)(H,27,28)
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.92E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240950
PNG
(US9409892, 45)
Show SMILES N[C@@H](CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O |r|
Show InChI InChI=1S/C21H18N4O5/c22-11-17-15-10-13(30-12-4-2-1-3-5-12)6-7-14(15)19(26)18(25-17)20(27)24-9-8-16(23)21(28)29/h1-7,10,16,26H,8-9,23H2,(H,24,27)(H,28,29)/t16-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.67E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240961
PNG
(US9409892, 56)
Show SMILES OC(=O)C(=O)CCNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C21H15N3O6/c22-11-16-15-10-13(30-12-4-2-1-3-5-12)6-7-14(15)19(26)18(24-16)20(27)23-9-8-17(25)21(28)29/h1-7,10,26H,8-9H2,(H,23,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
KEGG
PC cid
PC sid
UniChem
US Patent
n/an/a 1.80E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240971
PNG
(US9409892, 66)
Show SMILES CC(C)CC(CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C24H23N3O5/c1-14(2)10-15(11-21(28)29)26-24(31)22-23(30)18-9-8-17(12-19(18)20(13-25)27-22)32-16-6-4-3-5-7-16/h3-9,12,14-15,30H,10-11H2,1-2H3,(H,26,31)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.35E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240972
PNG
(US9409892, 67)
Show SMILES OC(=O)C[C@H](Cc1ccccc1)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O |r|
Show InChI InChI=1S/C27H21N3O5/c28-16-23-22-15-20(35-19-9-5-2-6-10-19)11-12-21(22)26(33)25(30-23)27(34)29-18(14-24(31)32)13-17-7-3-1-4-8-17/h1-12,15,18,33H,13-14H2,(H,29,34)(H,31,32)/t18-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.21E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240976
PNG
(US9409892, 71)
Show SMILES C[C@H](NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)[C@H](C)C(O)=O |r|
Show InChI InChI=1S/C22H19N3O5/c1-12(22(28)29)13(2)24-21(27)19-20(26)16-9-8-15(10-17(16)18(11-23)25-19)30-14-6-4-3-5-7-14/h3-10,12-13,26H,1-2H3,(H,24,27)(H,28,29)/t12-,13-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.07E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240978
PNG
(US9409892, 73)
Show SMILES C[C@](O)(CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O |r|
Show InChI InChI=1S/C21H17N3O6/c1-21(29,20(27)28)11-23-19(26)17-18(25)14-8-7-13(9-15(14)16(10-22)24-17)30-12-5-3-2-4-6-12/h2-9,25,29H,11H2,1H3,(H,23,26)(H,27,28)/t21-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.38E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240987
PNG
(US9409892, 82)
Show SMILES CC(C)(CC(O)=O)NC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O
Show InChI InChI=1S/C22H19N3O5/c1-22(2,11-18(26)27)25-21(29)19-20(28)15-9-8-14(10-16(15)17(12-23)24-19)30-13-6-4-3-5-7-13/h3-10,28H,11H2,1-2H3,(H,25,29)(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.04E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM240992
PNG
(US9409892, 87)
Show SMILES OC(=O)[C@H](CNC(=O)c1nc(C#N)c2cc(Oc3ccccc3)ccc2c1O)NC(=O)OCc1ccccc1 |r|
Show InChI InChI=1S/C28H22N4O7/c29-14-22-21-13-19(39-18-9-5-2-6-10-18)11-12-20(21)25(33)24(31-22)26(34)30-15-23(27(35)36)32-28(37)38-16-17-7-3-1-4-8-17/h1-13,23,33H,15-16H2,(H,30,34)(H,32,37)(H,35,36)/t23-/m0/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.75E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241002
PNG
(US9409892, 97)
Show SMILES OC(=O)CCNC(=O)c1nc(C#N)c2cc(Oc3ccc(F)cc3Cl)ccc2c1O
Show InChI InChI=1S/C20H13ClFN3O5/c21-14-7-10(22)1-4-16(14)30-11-2-3-12-13(8-11)15(9-23)25-18(19(12)28)20(29)24-6-5-17(26)27/h1-4,7-8,28H,5-6H2,(H,24,29)(H,26,27)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.43E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241006
PNG
(US9409892, 101)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(Oc3ccc(F)cc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C22H18FN3O5/c1-22(2,21(29)30)11-25-20(28)18-19(27)15-8-7-14(9-16(15)17(10-24)26-18)31-13-5-3-12(23)4-6-13/h3-9,27H,11H2,1-2H3,(H,25,28)(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.65E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241023
PNG
(US9409892, 118)
Show SMILES OC(=O)CCNC(=O)c1ncc2cc(NC(=O)c3ccc(F)cc3)ccc2c1O
Show InChI InChI=1S/C20H16FN3O5/c21-13-3-1-11(2-4-13)19(28)24-14-5-6-15-12(9-14)10-23-17(18(15)27)20(29)22-8-7-16(25)26/h1-6,9-10,27H,7-8H2,(H,22,29)(H,24,28)(H,25,26)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.13E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241028
PNG
(US9409892, 123)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2ccc(Oc3ccccc3)cc2c1O)C(O)=O
Show InChI InChI=1S/C22H19N3O5/c1-22(2,21(28)29)12-24-20(27)18-19(26)16-10-14(30-13-6-4-3-5-7-13)8-9-15(16)17(11-23)25-18/h3-10,26H,12H2,1-2H3,(H,24,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.83E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241031
PNG
(US9409892, 126)
Show SMILES COc1ccc(CNc2ccc3c(O)c(ncc3c2)C(=O)NCC(C)(C)C(O)=O)cc1
Show InChI InChI=1S/C23H25N3O5/c1-23(2,22(29)30)13-26-21(28)19-20(27)18-9-6-16(10-15(18)12-25-19)24-11-14-4-7-17(31-3)8-5-14/h4-10,12,24,27H,11,13H2,1-3H3,(H,26,28)(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241041
PNG
(US9409892, 136)
Show SMILES CC(C)(CNC(=O)c1nc(-c2cncc(F)c2)c2cc(Oc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C26H22FN3O5/c1-26(2,25(33)34)14-29-24(32)22-23(31)19-9-8-18(35-17-6-4-3-5-7-17)11-20(19)21(30-22)15-10-16(27)13-28-12-15/h3-13,31H,14H2,1-2H3,(H,29,32)(H,33,34)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241045
PNG
(US9409892, 140)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(NC(=O)Nc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C23H21N5O5/c1-23(2,21(31)32)12-25-20(30)18-19(29)15-9-8-14(10-16(15)17(11-24)28-18)27-22(33)26-13-6-4-3-5-7-13/h3-10,29H,12H2,1-2H3,(H,25,30)(H,31,32)(H2,26,27,33)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.35E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241053
PNG
(US9409892, 148)
Show SMILES OC(=O)CCCNC(=O)c1ncc2cc(ccc2c1O)-c1ccc(F)cc1
Show InChI InChI=1S/C20H17FN2O4/c21-15-6-3-12(4-7-15)13-5-8-16-14(10-13)11-23-18(19(16)26)20(27)22-9-1-2-17(24)25/h3-8,10-11,26H,1-2,9H2,(H,22,27)(H,24,25)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.45E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241064
PNG
(US9409892, 159)
Show SMILES OC(=O)C1(CNC(=O)c2nc(C#N)c3cc(OC4CCCCC4)ccc3c2O)CCC1
Show InChI InChI=1S/C23H25N3O5/c24-12-18-17-11-15(31-14-5-2-1-3-6-14)7-8-16(17)20(27)19(26-18)21(28)25-13-23(22(29)30)9-4-10-23/h7-8,11,14,27H,1-6,9-10,13H2,(H,25,28)(H,29,30)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.90E+3n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241065
PNG
(US9409892, 160)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(ccc2c1O)S(=O)(=O)C1CCCCC1)C(O)=O
Show InChI InChI=1S/C22H25N3O6S/c1-22(2,21(28)29)12-24-20(27)18-19(26)15-9-8-14(10-16(15)17(11-23)25-18)32(30,31)13-6-4-3-5-7-13/h8-10,13,26H,3-7,12H2,1-2H3,(H,24,27)(H,28,29)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.00E+5n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Egl nine homolog 1


(Homo sapiens (Human))		BDBM241067
PNG
(US9409892, 162)
Show SMILES CC(C)(CNC(=O)c1nc(C#N)c2cc(NC(=O)NCc3ccccc3)ccc2c1O)C(O)=O
Show InChI InChI=1S/C24H23N5O5/c1-24(2,22(32)33)13-27-21(31)19-20(30)16-9-8-15(10-17(16)18(11-25)29-19)28-23(34)26-12-14-6-4-3-5-7-14/h3-10,30H,12-13H2,1-2H3,(H,27,31)(H,32,33)(H2,26,28,34)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.41E+4n/an/an/an/a7.4n/a



FibroGen, Inc.

US Patent


Assay Description
Ketoglutaric acid α-[1-14C]-sodium salt, alpha-ketoglutaric acid sodium salt, and HPLC purified peptide may be obtained from commercial sources...

US Patent US9409892 (2016)


BindingDB Entry DOI: 10.7270/Q2MG7NFC
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 368 total )  |  Next  |  Last  >>
* indicates data uncertainty>20%