Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dipeptidyl peptidase 4 (642/728 = 88%)† (Homo sapiens (Human)) | BDBM50050521 ((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article | 3 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description In vitro test for inhibitory activity against human dipeptidyl peptidase IV. | Bioorg Med Chem Lett 6: 1163-1166 (1996) Article DOI: 10.1016/0960-894X(96)00190-4 BindingDB Entry DOI: 10.7270/Q279455Q | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dipeptidyl peptidase 4 (642/728 = 88%)† (Homo sapiens (Human)) | BDBM50050521 ((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 1.10 | n/a | n/a | n/a | n/a | 2.0 | n/a |
Trustees of Tufts College US Patent | Assay Description The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq... | US Patent US8933056 (2015) BindingDB Entry DOI: 10.7270/Q2ST7NJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dipeptidyl peptidase 4 (642/728 = 88%)† (Homo sapiens (Human)) | BDBM50050521 ((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 20 | n/a | n/a | n/a | n/a | n/a | n/a |
Boehringer Ingelheim Pharmaceuticals Inc. Curated by ChEMBL | Assay Description In vitro for inhibition of Dipeptidylpeptidase IV. | J Med Chem 39: 2087-94 (1996) Article DOI: 10.1021/jm950732f BindingDB Entry DOI: 10.7270/Q29Z95K5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dipeptidyl peptidase 4 (642/728 = 88%)† (Homo sapiens (Human)) | BDBM50050521 ((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 2.30E+4 | n/a | n/a | n/a | n/a | 8.0 | n/a |
Trustees of Tufts College US Patent | Assay Description The inhibitor solution is prepared by dissolving 3-5 mg of inhibitor in pH 2 solution (0.01 N HCl), such that the concentration of the solution is eq... | US Patent US8933056 (2015) BindingDB Entry DOI: 10.7270/Q2ST7NJQ | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Dipeptidyl peptidase 4 (642/728 = 88%)† (Homo sapiens (Human)) | BDBM50050521 ((2-Dihydroxyborane-pyrrolidin-1-yl)-pyrrolidin-2-y...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 8.48E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
University of Tokyo Curated by ChEMBL | Assay Description Inhibitory activity against dipeptidyl peptidase IV (DPP- IV) | J Med Chem 41: 263-5 (1998) Article DOI: 10.1021/jm970624o BindingDB Entry DOI: 10.7270/Q24X5BJC | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |