Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Neutrophil collagenase (163/163 = 100%)† (Homo sapiens (Human)) | BDBM50035235 (CHEMBL2372437 | N-[1-(Carbamoylmethyl-carbamoyl)-e...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | 1.21E+5 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Institut für Biochemie Curated by ChEMBL | Assay Description Inhibition of Matrix metalloproteinase-8 (Human neutrophil collagenase, MMP-8) | J Med Chem 41: 339-45 (1998) Article DOI: 10.1021/jm9706426 BindingDB Entry DOI: 10.7270/Q2639NWF | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |