Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Nitric oxide synthase, endothelial (414/415 > 99%)† (Homo sapiens (Human)) | BDBM50290811 (5-Chloro-3H-benzooxazol-2-one | 5-Chloro-benzooxaz...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL DrugBank MCE MMDB PC cid PC sid PDB UniChem Patents | PDB Article | n/a | n/a | 8.70E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA Curated by ChEMBL | Assay Description Inhibitory activity against Endothelial nitric oxide synthase | Bioorg Med Chem Lett 7: 2887-2892 (1997) Article DOI: 10.1016/S0960-894X(97)10101-9 BindingDB Entry DOI: 10.7270/Q28G8KQD | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |