Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Prothrombin (259/259 = 100%)† (Homo sapiens (Human)) | BDBM50126652 (2-METHANESULFONYL-BENZENESULFONIC ACID 3-METHYL-5-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB PubMed | 7.70 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
3-Dimensional Pharmaceuticals, Inc. Curated by ChEMBL | Assay Description Inhibitory activity of the compound was tested against alpha-human thrombin | Bioorg Med Chem Lett 13: 1495-8 (2003) BindingDB Entry DOI: 10.7270/Q2668CJ9 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |