Affinity Data by PDB ID

PDB code 3DPE

Found 1 hit Enzyme Inhibition Constant Data
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Neutrophil collagenase (163/163 = 100%)^† (Homo sapiens (Human))	BDBM27877 (N-{[2-(2-amino-3,4-dioxocyclobut-1-en-1-yl)-1,2,3,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	MMDB PC cid PC sid PDB UniChem Patents	MMDB PDB Article PubMed	n/a	n/a	57	n/a	n/a	n/a	n/a	7.5	22
Universita degli Studi					Assay Description Inhibition of the matrix metalloproteinases MMPs has been determined by continuously monitoring the hydrolysis of the fluorescent substrate. The hydr...				J Med Chem 52: 1040-9 (2009) Article DOI: 10.1021/jm801166j BindingDB Entry DOI: 10.7270/Q28S4N80
Universita degli Studi					More data for this Ligand-Target Pair				3D Structure (crystal)

_* indicates data uncertainty>20%
* 0.9 Tanimoto similarity
† Identities from BLAST output