Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (94/94 = 100%)† (Homo sapiens (Human)) | BDBM26357 (3-chloroindole compound, 18 | methyl (2Z)-3-[(3-ch...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 8.90 | n/a | n/a | n/a | n/a | 7.4 | 22 |
Bristol-Myers Squibb Company | Assay Description Time-dependent optical density change was followed at 405 nm using a kinetic microplate reader at room temperature. Enzyme activity in the presence o... | J Med Chem 51: 7541-51 (2008) Article DOI: 10.1021/jm800855x BindingDB Entry DOI: 10.7270/Q2V12332 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |