Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Coagulation factor VIII (159/159 = 100%)† (Homo sapiens (Human)) | BDBM50423622 (CHEMBL1614804) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 7.80E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Maastricht University Curated by ChEMBL | Assay Description Inhibition of human factor 8 binding to immobilized phospholipid by surface plasmon resonance assay | Proc Natl Acad Sci USA 104: 12697-702 (2007) Article DOI: 10.1073/pnas.0701051104 BindingDB Entry DOI: 10.7270/Q2F190MG | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |