Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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Polyunsaturated fatty acid lipoxygenase ALOX15 (547/552 > 99%)† (Sus scrofa) | BDBM50054838 (3-(4-Tridec-2-ynyloxymethyl-phenyl)-propionic acid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | n/a | n/a | 35 | n/a | n/a | n/a | n/a | n/a | n/a |
Wayne State University Curated by ChEMBL | Assay Description Inhibitory activity against conversion of [1-14C]-arachidonic acid to 12-HPETE and its reduction product 12-HETE by porcine leukocyte type 12-lipoxyg... | J Med Chem 39: 4871-8 (1997) Article DOI: 10.1021/jm9606047 BindingDB Entry DOI: 10.7270/Q2BR8R81 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |