Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Coagulation factor X (54/54 = 100%)† (Homo sapiens (Human)) | BDBM50338329 (CHEMBL1681798 | N-(2-{3-[(5-Chlorothiophen-2-yl)ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of human factor 10a using S-2222 as substrate by spectrophotometry | Bioorg Med Chem Lett 21: 7337-43 (2011) Article DOI: 10.1016/j.bmcl.2011.10.021 BindingDB Entry DOI: 10.7270/Q2V40VM5 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) | ||||||||||||
Coagulation factor X (54/54 = 100%)† (Homo sapiens (Human)) | BDBM50338329 (CHEMBL1681798 | N-(2-{3-[(5-Chlorothiophen-2-yl)ca...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | CHEMBL MMDB PC cid PC sid PDB UniChem Similars | PDB Article PubMed | n/a | n/a | 1.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Daiichi Sankyo Co., Ltd Curated by ChEMBL | Assay Description Inhibition of factor 10a by S2222 chromogenic substrate assay by chromogenic assay | Bioorg Med Chem 19: 1623-42 (2011) Article DOI: 10.1016/j.bmc.2011.01.035 BindingDB Entry DOI: 10.7270/Q22F7NR3 | |||||||||||
More data for this Ligand-Target Pair | 3D Structure (crystal) |